Biophotonic tools for probing extracellular matrix mechanics

Autor: B.E. Sherlock, J. Chen, J.C. Mansfield, E. Green, C.P. Winlove

Publikováno v: Matrix Biology Plus, Vol 12, Iss , Pp 100093- (2021)

The complex, hierarchical and heterogeneous biomechanics of the extracellular matrix (ECM) are central to the health of multicellular organisms. Characterising the distribution, dynamics and above all else origins of ECM biomechanics are challenges t

Externí odkaz: https://doaj.org/article/978a120e3aae46f4b1f699aba73a0920

Micro-mechanical damage of needle puncture on bovine annulus fibrosus fibrils studied using polarization-resolved Second Harmonic Generation(P-SHG) microscopy

Autor: Claudio Vergari, Jessica C. Mansfield, Judith R. Meakin, J.-Y. Wang, C.P. Winlove, Sophie Brasselet

Publikováno v: Journal of the mechanical behavior of biomedical materials
Journal of the mechanical behavior of biomedical materials, Elsevier, 2021, 118, pp.104458. ⟨10.1016/j.jmbbm.2021.104458⟩
Journal of the mechanical behavior of biomedical materials, 2021, 118, pp.104458. ⟨10.1016/j.jmbbm.2021.104458⟩

International audience; Needle injection has been widely used in spinal therapeutic or diagnostic processes, such as discography. The use of needles has been suspected in causing mild disc degeneration which can lead to long-term back pain. However,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94673a06533195b87fbfe2043a0312fa
https://doi.org/10.1016/j.jmbbm.2021.104458

Assessment of Compressive Raman versus Hyperspectral Raman for Microcalcification Chemical Imaging

Autor: C.P. Winlove, Hervé Rigneault, Pascaline Bouzy, Didier Marguet, Hilton B. de Aguiar, Nicholas Stone, Sébastien Vergnole, Ellen Green, Camille Scotté

Publikováno v: Analytical Chemistry
Analytical Chemistry, 2018, 90 (12), pp.7197-7203. ⟨10.1021/acs.analchem.7b05303⟩
Analytical Chemistry, American Chemical Society, 2018, 90 (12), pp.7197-7203. ⟨10.1021/acs.analchem.7b05303⟩

International audience; We experimentally implement a compressive Raman technology (CRT) that incorporates chemometricanalysis directly into the spectrometer hardware by means of a digital micromirror device (DMD). The DMD is a programmable optical f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0731f55cbd1c829748e7f6513e59d584
https://hal-amu.archives-ouvertes.fr/hal-01816013/file/AnalChem2018_postprint.pdf

Inexact Bayesian point pattern matching for linear transformations

Autor: C.P. Winlove, Richard M. Everson, James Stephen Bell, Jacqueline Christmas

Publikováno v: Pattern Recognition. 47:3265-3275

We introduce a novel Bayesian inexact point pattern matching model that assumes that a linear transformation relates the two sets of points. The matching problem is inexact due to the lack of one-to-one correspondence between the point sets and the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b4b06f002e23c364bec0cb9c9d27c693
https://doi.org/10.1016/j.patcog.2014.04.022

Micromechanical response of articular cartilage to tensile load measured using nonlinear microscopy

Autor: James Stephen Bell, C.P. Winlove, Richard M. Everson, Jessica C. Mansfield, Jacqueline Christmas

Publikováno v: Acta Biomaterialia. 10:2574-2581

Articular cartilage (AC) is a highly anisotropic biomaterial, and its complex mechanical properties have been a topic of intense investigation for over 60 years. Recent advances in the field of nonlinear optics allow the individual constituents of AC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::043c84f2286404d59e0cd5ce911e84c3
https://doi.org/10.1016/j.actbio.2014.02.008