Výsledky vyhledávání - "C.M. Semeins"

Mechanical Loading Differentially Affects Osteocytes in Fibulae from Lactating Mice Compared to Osteocytes in Virgin Mice: Possible Role for Lacuna Size

Autor: Haniyeh Hemmatian, Jolanda M. A. Hogervorst, Astrid D. Bakker, G. Harry van Lenthe, C.M. Semeins, Rozita Jalali, Jenneke Klein-Nulend

Publikováno v: Calcified Tissue International, 103(6), 675-685. Springer New York
Hemmatian, H, Jalali, R, Semeins, C M, Hogervorst, J M A, van Lenthe, G H, Klein-Nulend, J & Bakker, A D 2018, ' Mechanical loading differentially affects osteocytes in fibulae from lactating mice compared to osteocytes in virgin mice: Possible role for lacuna size ', Calcified Tissue International, vol. 103, no. 6, pp. 675-685 . https://doi.org/10.1007/s00223-018-0463-8
Calcified Tissue International

Hormonal changes during lactation are associated with profound changes in bone cell biology, such as osteocytic osteolysis, resulting in larger lacunae. Larger lacuna shape theoretically enhances the transmission of mechanical signals to osteocytes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ce4264a1a5184f2fc9241d08501a644
https://doi.org/10.1007/s00223-018-0463-8

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Comprehensive transcriptome analysis of fluid shear stress altered gene expression in renal epithelial cells

Autor: Tareq B. Malas, C.M. Semeins, Dorien J.M. Peters, Steven J. Kunnen, Astrid D. Bakker

Publikováno v: Journal of Cellular Physiology, 233(4), 3615-3628. Wiley-Liss Inc.
Journal of Cellular Physiology, 233(4), 3615-3628
Kunnen, S J, Malas, T B, Semeins, C M, Bakker, A D & Peters, D J M 2018, ' Comprehensive transcriptome analysis of fluid shear stress altered gene expression in renal epithelial cells ', Journal of Cellular Physiology, vol. 233, no. 4, pp. 3615-3628 . https://doi.org/10.1002/jcp.26222
Journal of Cellular Physiology

Renal epithelial cells are exposed to mechanical forces due to flow-induced shear stress within the nephrons. Shear stress is altered in renal diseases caused by tubular dilation, obstruction, and hyperfiltration, which occur to compensate for lost n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4726b9c4a87e9d702906ad6be69d480
https://doi.org/10.1002/jcp.26222

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Supraphysiological loading induces osteocyte-mediated osteoclastogenesis in a novel in vitro model for bone implant loosening

Autor: Astrid D. Bakker, Jenneke Klein-Nulend, C.M. Semeins, Cornelia Bratengeier, Anna Fahlgren

Publikováno v: Journal of Orthopaedic Research®. 36:1425-1434

We aimed to develop an in vitro model for bone implant loosening, allowing analysis of biophysical and biological parameters contributing to mechanical instability-induced osteoclast differentiatio ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4db299ca2299a03a65136df921ca8dce
https://doi.org/10.1002/jor.23780

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Mechanoresponsiveness of human adipose stem cells on nanocomposite and micro-hybrid composite

Autor: Jenneke Klein-Nulend, Fransisca A. S. van Esterik, Samaneh Ghazanfari, Behrouz Zandieh-Doulabi, Cornelis J. Kleverlaan, C.M. Semeins

Publikováno v: Journal of Biomedical Materials Research Part A. 105:2986-2994

Resin-based composites are used for bone repair applications and comprise resin matrix and different sized filler particles. Nanometer-sized filler particles improve composite's mechanical properties compared with micrometer-sized filler particles, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0556d7a641a64b6f011ace5f892adc84
https://doi.org/10.1002/jbm.a.36149

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Influence of nanostructural environment and fluid flow on osteoblast-like cell behavior: A model for cell-mechanics studies

Autor: Jenneke Klein-Nulend, John A. Jansen, J.J.W.A. van Loon, C.M. Semeins, X.F. Walboomers, Ljupcho Prodanov, J. te Riet

Publikováno v: Prodanov, L, Semeins, C M, van Loon, J J W A, te Riet, J, Jansen, J A, Klein-Nulend, J & Walboomers, X F 2013, ' Influence of nanostructural environment and fluid flow on osteoblast-like cell behavior: A model for cell-mechanics studies ', Acta Biomaterialia, vol. 9, no. 5, pp. 6653-6662 . https://doi.org/10.1016/j.actbio.2013.02.011
Prodanov, L, Semeins, C M, van Loon, J J W A, te Riet, J, Jansen, J A, Klein-Nulend, J & Walboomers, X F 2013, ' Influence of nanostructural environment and fluid flow on osteoblast-like cell behavior: a model for cell-mechanics studies ', Acta Biomaterialia, vol. 9, no. 5, pp. 6653-6662 . https://doi.org/10.1016/j.actbio.2013.02.011
Acta Biomaterialia, 9(5), 6653-6662. Elsevier BV
Acta Biomaterialia, 9, 6653-62
Acta Biomaterialia, 9(5), 6653-6662. Elsevier
Acta Biomaterialia, 9, 5, pp. 6653-62

Item does not contain fulltext Introducing nanoroughness on various biomaterials has been shown to profoundly effect cell-material interactions. Similarly, physical forces act on a diverse array of cells and tissues. Particularly in bone, the tissue

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8f1c55d281a383ec0a7184576b8adc7
https://doi.org/10.1016/j.actbio.2013.02.011

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Differences in proliferation, differentiation, and cytokine production by bone cells seeded on titanium–nitride and cobalt–chromium–molybdenum surfaces

Autor: Jenneke Klein-Nulend, Ruud P. van Hove, Peter A. Nolte, C.M. Semeins

Publikováno v: Journal of Biomaterials Applications, 28(2), 278-287. SAGE Publications Ltd
van Hove, R P, Nolte, P A, Semeins, C M & Klein-Nulend, J 2013, ' Differences in proliferation, differentiation, and cytokine production by bone cells seeded on titanium-nitride and cobalt-chromium-molybdenum surfaces ', Journal of Biomaterials Applications, vol. 28, no. 2, pp. 278-287 . https://doi.org/10.1177/0885328212440600

Titanium–nitride coating is used to improve cobalt–chromium–molybdenum implant survival in total knee arthroplasty, but its effect on osteoconduction is unknown. Chromium and cobalt ions negatively affect the growth and metabolism of cultured o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::834b15e3122506c1893cbe7cd9e25fa3
https://doi.org/10.1177/0885328212440600

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Opposite effects of osteogenic protein and transforming growth factor β on chondrogenesis in cultured long bone rudiments

Autor: T K Sampath, Jenneke Klein Nulend, Elisabeth H. Burger, M.N. Helder, S.C. Dieudonné, S. W. Goei, Slobodan Vukicevic, C.M. Semeins

Publikováno v: Journal of Bone and Mineral Research. 9:771-780

Osteogenic protein-1 (OP-1, also called BMP-7) is a bone morphogenetic member of the TGF-beta superfamily. In the present study, we examined the effect of recombinant human OP-1 on cartilage and bone formation in organ cultures of metatarsal long bon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d8252bda4789410dc5ae10ad87c94f
https://doi.org/10.1002/jbmr.5650090603

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Pulsating fluid flow modulates gene expression of proteins involved in Wnt signaling pathways in osteocytes

Autor: Jenneke Klein-Nulend, C.M. Semeins, Astrid D. Bakker, Behrouz Zandieh-Doulabi, Ana Santos

Publikováno v: Journal of Orthopaedic Research. 27:1280-1287

Strain-derived flow of interstitial fluid activates signal transduction pathways in osteocytes that regulate bone mechanical adaptation. Wnts are involved in this process, but whether mechanical loading modulates Wnt signaling in osteocytes is unclea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::edab936b74e79de4d0b91474ac1e03a3
https://doi.org/10.1002/jor.20888

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