Current diagnostic problems in melanoma pathology

Autor: Marcory C. R. F. van Dijk, Dirk J. Ruiter, C.M. Ferrier

Publikováno v: Seminars in Cutaneous Medicine and Surgery, 22, 1, pp. 33-41
Seminars in Cutaneous Medicine and Surgery, 22, 33-41

Item does not contain fulltext The histopathological diagnosis of cutaneous melanocytic lesions may be difficult to assess. Frequently encountered diagnostic problems include: 1) Dysplastic nevus or melanoma in situ?; 2) Melanoma in situ or superfici

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b11d8ebf6d55e44d56637e92ce6a272
https://hdl.handle.net/2066/222502

High tPA-expression in primary melanoma of the limb correlates with good prognosis

Autor: H. Schraffordt Koops, Dirk J. Ruiter, Huub Straatman, Ulrich R. Kleeberg, Ferdy Lejeune, Stefan Suciu, A. M. M. Eggermont, W. van Geloof, B. B. R. Kroon, C.M. Ferrier, G.N.P. van Muijen

Publikováno v: British Jounal of Cancer, 83(10), 1351-1359. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer, 83, 1351-1359
British Journal of Cancer, 83, pp. 1351-1359
British Journal of Cancer, vol. 83, no. 10, pp. 1351-1359
British Journal of Cancer, 83(10), 1351-1359. Nature Publishing Group

To investigate whether the course of primary melanoma disease correlates with expression of the various components of the proteolytic plasminogen activation (PA) system, immunohistochemical stainings for activators of plasminogen (tissue type (tPA) a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4641a9f4650950d18b07504f37662c3
https://research.rug.nl/en/publications/b015fe37-00a2-43de-89eb-1ceec80362df

Epitopes of components of the plasminogen activation system are re-exposed in formalin-fixed paraffin sections by different retrieval techniques

Autor: Hans H. de Witte, Winny L. van Geloof, Goos N.P. van Muijen, Dirk J. Ruiter, Michael D. Kramer, C.M. Ferrier

Publikováno v: Journal of Histochemistry and Cytochemistry, 46, 469-476
Journal of Histochemistry and Cytochemistry, 46, pp. 469-476

We present a systematic analysis of the sensitivity and specificity of immunohistochemical stainings for components of the plasminogen activation system, i.e., uPA, tPA, PAI-1, PAI-2, and uPAR, on routinely processed (formalin-fixed, paraffin-embedde

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ca80d9d0e5d2d5c798383cefebf5c6
http://hdl.handle.net/2066/184917

Proteases in cutaneous melanoma

Autor: C.M. Ferrier, Dirk J. Ruiter, G.N.P. van Muijen

Publikováno v: Annals of Medicine, 30, 431-442
Annals of Medicine, 30, pp. 431-442

From a great number of studies there is clear evidence that several extracellular proteolytic enzymes play an important role in various tumour-related processes. This review focusses on proteases in cutaneous melanoma. The current knowledge on and in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17daf896e46a2b6389782466029bd8d7
http://hdl.handle.net/2066/224615

Effects of topical treatment with budesonide on parameters for epidermal proliferation, keratinization and inflammation in psoriasis

Autor: C.M. Ferrier, P.J.J. Wauben-Penris, C. Korstanje, E.M.G.J. de Jong, P.C.M. van de Kerkhof, A. J. De Zwart

Publikováno v: Journal of Dermatological Science, 9, 185-194
Journal of Dermatological Science, 9, 3, pp. 185-194
Journal of Dermatological Science, 9, pp. 185-194

Corticosteroids are important in the treatment of inflammatory dermatoses, such as psoriasis. They have anti-inflammatory, anti-proliferative and immunosuppressive effects. In this study, the effect of budesonide on proliferation, inflammatory cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc0048e83b6906debfd1ec21e694fb3
http://hdl.handle.net/2066/151846