Evaluation of the skeletal effects of combined mild dietary calcium restriction and ovariectomy in sinclair S-1 minipigs: A pilot study

Autor: Steven E. Weisbrode, C.H. Søgaard, Joseph A. Safron, Harold F. Stills, M.L. Stevens, Rogely Waite Boyce, C.L. Paddock, Alan F. Franks, Carl Christian Danielsen, Maryann L. Jankowsky, D.C. Ebert, Lis Mosekilde

Publikováno v: Mosekilde, L, Weisbrode, S E, Safron, J A, Stills, H F, Jankowsky, M L, Ebert, D C, Danielsen, C C, Søgaard, C, Franks, A F & Stevens, M L 1993, ' Evaluation of the skeletal effects of combined mild dietary calcium restriction and ovariectomy in Sinclair S-1 minipigs : a pilot study ', Journal of Bone and Mineral Research, vol. 8, no. 11, pp. 1311-21 . https://doi.org/10.1002/jbmr.5650081106

A pilot study was conducted to investigate the combined effects of ovariectomy (OVX) with preceding and concomitant mild dietary calcium restriction on the minipig skeleton. Minipigs 4 months old were fed diets containing 0.9, 0.75, or 0.5% calcium (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aee5c66014b5489b4b5aec8c6a92ef47
https://doi.org/10.1002/jbmr.5650081106

The effects of risedronate on canine cancellous bone remodeling: Three-dimensional kinetic reconstruction of the remodeling site

Autor: E.F. Eriksen, Rogely Waite Boyce, C.L. Paddock, J.R. Gleason, W.K. Sletsema

Publikováno v: Journal of Bone and Mineral Research. 10:211-221

To investigate the dose-dependent effects of risedronate on cancellous bone remodeling, adult female beagle dogs were treated with either placebo, 0.1, 0.5, or 2.5 mg/kg/day of risedronate orally in an intermittent cyclic regimen (7 days on 21 days o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8f33285cad38f7a34e03f1cb1ea8f0
https://doi.org/10.1002/jbmr.5650100207

Direct stereological estimation of three-dimensional connectivity in rat vertebrae: effect of estrogen, etidronate and risedronate following ovariectomy

Autor: Rogely Waite Boyce, Hans Jørgen G. Gundersen, C.L. Paddock, Thomas J. Wronski, M.L. Stevens, T.A. Youngs, D.C. Ebert

Publikováno v: Bone. 16(2)

Newly developed unbiased stereological methods were employed to investigate the effects of estrogen deficiency on the three-dimensional connectivity of vertebral cancellous bone from ovariectomized (OVX) rats. The effects of two classes of antiresorp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15435e687a0e70471bb165a3d2a016cf
https://pubmed.ncbi.nlm.nih.gov/7756049

Calcium-restricted ovariectomized sinclair s-1 minipigs: An animal model of osteopenia and trabecular plate perforation

Autor: Harold F. Stills, Steven E. Weisbrode, C.H. Søgaard, Joseph A. Safron, Lis Mosekilde, M.L. Stevens, C.L. Paddock, Maryann L. Jankowsky, Rogely Waite Boyce, Carl Christian Danielsen, Alan F. Franks, D.C. Ebert

Publikováno v: Bone. 13:A24-A24

The ovariectomized rat model has now been generally accepted as a useful model for screening different therapeutic agents, but there is a major requirement to identify reliable large animal models for osteoporosis research. In this study, the calcium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bb33371bb0ad3ced1f7acec521a0a33
https://doi.org/10.1016/8756-3282(92)90551-7

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