Zobrazeno 1 - 10
of 121
pro vyhledávání: '"C.K. Hill"'
Publikováno v:
Health physics. 117(5)
This paper summarizes about 9 years of effort by Mount Sinai to successfully migrate completely from radioactive irradiators to x-ray irradiators without compromising patient care or research studies. All the effort by Mount Sinai to permanently remo
Autor:
Jay L. Nadeau, C.K. Hill, Konstantin Kudinov, Devesh Bekah, Daniel R. Cooper, Stephen E. Bradforth, Jan Seuntjens
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 329:26-34
There has been significant recent interest in combining radiation therapy and photodynamic therapy for cancer treatment. One proposed method involves conjugating photosensitizers (PS) to scintillating nanoparticles. However, the production of nanosci
Autor:
Gere S. diZerega, Christopher J. Meeks, C.K. Hill, Holly Maulhardt, William Johnston, Melissa Donald, Theresa Espinoza, Kathleen E. Rodgers, Lila Kim, Alick Tan
Publikováno v:
International Journal of Radiation Biology. 92:434-443
A guinea pig skin model was developed to determine the dose-dependent response to soft X-ray radiation into the dermis.X-ray exposure (50 kVp) was defined to a 4.0 × 4.0 cm area on the lateral surface of a guinea pig using lead shielding. Guinea pig
Autor:
C.K. Hill, Stan G. Louie, Gere S. diZerega, Christopher J. Meeks, Kathleen E. Rodgers, Norma Roda, Sachin Suresh Jadhav, Theresa Espinoza, Nicholas M. Mordwinkin, Natasha Sharma
Publikováno v:
Wound Repair and Regeneration. 21:131-140
The renin-angiotensin system (RAS) plays an important role in wound repair; however, little is known pertaining to RAS expression in response to thermal injury and the combination of radiation plus burn injury (CRBI). The purpose of this study was to
Autor:
Konstantin Kudinov, C.K. Hill, Daniel R. Cooper, Jay L. Nadeau, Devesh Bekah, Sathvik Shastry, Stephen E. Bradforth
Publikováno v:
SPIE Proceedings.
Dense inorganic nanoparticles have recently been identified as promising radiosensitizers. In addition to dose enhancement through increased attenuation of ionizing radiation relative to biological tissue, scintillating nanoparticles can transfer ene
Autor:
Gere S. diZerega, Christopher J. Meeks, C.K. Hill, Stan G. Louie, Norma Roda, Kathleen E. Rodgers, Theresa Espinoza
Publikováno v:
International Journal of Radiation Biology. 88:466-476
PURPOSE: Angiotensin (1–7) [A(1–7)] is a component of the renin angiotensin system (RAS) that stimulates hematopoietic recovery after myelosuppression. In a Phase I/IIa clinical trial, thrombocytopenia after chemotherapy was reduced by A(1–7).
Autor:
Jay L. Nadeau, C.K. Hill, Konstantin Kudinov, Jan Seuntjens, J Ha, Stephen E. Bradforth, Daniel R. Cooper
Publikováno v:
Radiation Research. 190:28
A hybrid of radiotherapy and photodynamic therapy (PDT) has been proposed in previously reported studies. This approach utilizes scintillating nanoparticles to transfer energy to attached photosensitizers, thus generating singlet oxygen for local kil
Autor:
C.K. Hill, Rula Harb, Laurie D. DeLeve, Gary Kanel, Yumei Guo, Carolyn Lutzko, Guanhua Xie, Xiangdong Wang
Publikováno v:
Gastroenterology. 137:704-712
Background & Aims Damage to hepatic sinusoidal endothelial cells (SECs) initiates sinusoidal obstruction syndrome (SOS), which is most commonly a consequence of myeloablative chemoirradiation or ingestion of pyrrolizidine alkaloids such as monocrotal
Autor:
C.K. Hill, Daniel R. Cooper, Devesh Bekah, J Ha, Konstantin Kudinov, Jay L. Nadeau, Dhrittiman Bhattacharyya, Pooja Tyagi, Stephen E. Bradforth
Publikováno v:
SPIE Proceedings.
We report progress towards combining radiation therapy (RT) and photodynamic therapy (PDT) using scintillating nanoparticle (NP)-photosensitizer conjugates. In this approach, scintillating NPs are excited by clinically relevant ionizing radiation sou
Autor:
Pooja Tyagi, Daniel R. Cooper, C.K. Hill, Jay L. Nadeau, Konstantin Kudinov, Stephen E. Bradforth
Publikováno v:
Physical chemistry chemical physics : PCCP. 16(24)
CexLa1-xF3 nanoparticles have been proposed for use in nanoscintillator-photosensitizer systems, where excitation of nanoparticles by ionizing radiation would result in energy transfer to photosensitizer molecules, effectively combining the effects o