Zobrazeno 1 - 10
of 129
pro vyhledávání: '"C.J. de Blaey"'
Autor:
Marcel L. Bouvy, C.J. de Blaey, Aukje K. Mantel-Teeuwisse, OH Klungel, A. de Boer, M.E. van der Elst
Publikováno v:
Drug Safety. 29:911-1010
Autor:
C.J. de Blaey, H. Van der Graaff
Publikováno v:
Journal of Pharmaceutical Sciences. 66:1696-1699
An equation describing the isotropical dissolution of soluble nondisintegrating disks was developed. It was equivalent to the cube root law only if the height and diameter of the disk were equal. The dissolution kinetics of sodium chloride disks were
Publikováno v:
Pharmaceutisch weekblad. 1:1470-1473
The bioavailability of pentobarbital sodium was studied in humans, as a function of the size of particles dispersed in fatty suppositories. It was found that particles of 90–100Μm exhibit a faster absorption rate compared with particles smaller th
Publikováno v:
Powder Technology. 26:169-185
On an instrumented single-punch press, working at an overall rate of 30 strokes per minute, the influence of diameter of punches and die on upper and lower punch pressure, measured during the densification of a powder with an initial height of 8.0 mm
Publikováno v:
Powder Technology. 28:147-165
With a microgranulation of lactose, experiments at various diameters of punches and die, namely from 7 to 17 mm, have been performed in order to determine the influence of the diameter on the pressure required to achieve a given state of density duri
Publikováno v:
International Journal of Pharmaceutics. 3:299-309
The rectal absorption of theophylline was investigated in situ in rats as a function of luminal pH. As the pH near the membrane may deviate from the luminal pH by secretion, the neutralizing capacity of the rectum was determined by perfusing phosphat
Publikováno v:
Journal of Pharmaceutical Sciences. 73:1771-1774
With the aid of rapidly dissolving sodium chloride particles, cubic pores were made in the surface of a theophylline tablet. The influence of the pores on the dissolution rate of the surface was investigated in a rotating disk apparatus. Like the dri
Publikováno v:
International Journal of Pharmaceutics. 3:293-297
The influence of pores on the dissolution rate of non-disintegating sodium chloride tablets was investigated. Artificial pores of different diameters were created by drilling in highly compressed tablets. The dissolution rate increase appearen to be
Publikováno v:
Pharmaceutisch weekblad. 1:196-200
A methadone resin salt for oral administration was produced in order to prevent, or at least diminish, the abuse of methadone during a maintenance programme with heroin-addicts. This salt will also lead to a more continuous release of the drug, depen
Publikováno v:
International Journal of Pharmaceutics. 3:187-194
The influence of particle size and concentration of lithium sulphate on the bioavailability in rats is reported. Particles