Zobrazeno 1 - 10
of 28
pro vyhledávání: '"C.J. Okumura"'
Autor:
Heather M. Callaway, Kathryn M. Hastie, Sharon L. Schendel, Haoyang Li, Xiaoying Yu, Jeremy Shek, Tierra Buck, Sean Hui, Dan Bedinger, Camille Troup, S. Moses Dennison, Kan Li, Michael D. Alpert, Charles C. Bailey, Sharon Benzeno, Jody L. Bonnevier, Jin-Qiu Chen, Charm Chen, Hyeseon Cho, Peter D. Crompton, Vincent Dussupt, Kevin C. Entzminger, Yassine Ezzyat, Jonathan K. Fleming, Nick Geukens, Amy E. Gilbert, Yongjun Guan, Xiaojian Han, Christopher J. Harvey, Julia M. Hatler, Bryan Howie, Chao Hu, Ailong Huang, Maya Imbrechts, Aishun Jin, Nik Kamachi, Gladys Keitany, Mark Klinger, Jay K. Kolls, Shelly J. Krebs, Tingting Li, Feiyan Luo, Toshiaki Maruyama, Michael A. Meehl, Letzibeth Mendez-Rivera, Andrea Musa, C.J. Okumura, Benjamin E.R. Rubin, Aaron K. Sato, Meiying Shen, Anirudh Singh, Shuyi Song, Joshua Tan, Jeffrey M. Trimarchi, Dhruvkumar P. Upadhyay, Yingming Wang, Lei Yu, Tom Z. Yuan, Erik Yusko, Bjoern Peters, Georgia Tomaras, Erica Ollmann Saphire
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 112014- (2023)
Summary: The SARS-CoV-2 Omicron variant of concern (VoC) and its sublineages contain 31–36 mutations in spike and escape neutralization by most therapeutic antibodies. In a pseudovirus neutralization assay, 66 of the nearly 400 candidate therapeuti
Externí odkaz:
https://doaj.org/article/61e61f138daa45d1ba9a2edb473cf0bc
Autor:
Teruo Akuta, C.J. Okumura, Yasunori Kurosawa, Chiaki Sakuma, Takashi Shibata, Tsutomu Arakawa, Toshiaki Maruyama, Tomomi Sato, Masataka Nakagawa
Publikováno v:
International Journal of Biological Macromolecules. 166:1106-1110
Western blotting was attempted to analyze proteins separated by agarose native gel electrophoresis that was previously developed on His/Mes buffer system. This report shows a simple protocol for blotting agarose native gel to a PVDF membrane by soaki
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f7703f2efffd423f34a4bb4d4355759
https://doi.org/10.1016/j.ijbiomac.2020.10.265
https://doi.org/10.1016/j.ijbiomac.2020.10.265
Autor:
Takanori Yokoo, Aki Tanabe, Yoko Yoshida, Jose M.M. Caaveiro, Makoto Nakakido, Yoichiro Ikeda, Yoshihiro Fujimura, Masaneori Matsumoto, Kevin Entzminger, Toshiaki Maruyama, C.J. Okumura, Masaomi Nangaku, Kouhei Tsumoto
Publikováno v:
J Biol Chem
Atypical hemolytic uremic syndrome (aHUS) is a disease associated with dysregulation of the immune complement system, especially of the alternative pathway (AP). Complement factor H (CFH), consisting of 20 domains called complement control protein (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06490d18e155ce302f1960c31539cef9
https://pubmed.ncbi.nlm.nih.gov/35868160
https://pubmed.ncbi.nlm.nih.gov/35868160
Autor:
C.J. Okumura, Josh W. Bramley, Yasunori Kurosawa, Ivo Lieberam, Susumu Goyama, Yasushi Kubota, Chiaki Sakuma, Teruo Akuta, Toshio Kitamura, Takashi Shibata, Yosuke Tanaka, Masataka Nakagawa, Shinya Kimura, David G. Kent, Thomas M. Jessell, Toshiaki Maruyama, Jillian L. Barlow
Numerous strategies exist to isolate hematopoietic stem cells (HSCs) using complex combinations of markers and flow cytometry. However, robust identification of HSCs using imaging techniques is substantially more challenging which has prompted the re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f038844cd8b919d801ba280bcf7c36f
https://doi.org/10.1101/2021.09.27.461900
https://doi.org/10.1101/2021.09.27.461900
Autor:
Takanori Yokoo, Aki Tanabe, Yoko Yoshida, Jose M.M. Caaveiro, Makoto Nakakido, Yoichiro Ikeda, Yoshihiro Fujimura, Masaneori Matsumoto, Kevin Entzminger, Toshiaki Maruyama, C.J. Okumura, Masaomi Nangaku, Kouhei Tsumoto
Publikováno v:
Journal of Biological Chemistry. 298:102262
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::583273d32b7c6c6e9839afced67e171f
https://doi.org/10.1016/j.jbc.2022.102262
https://doi.org/10.1016/j.jbc.2022.102262
Autor:
Chiaki Sakuma, Taiji Furukawa, Takashi Shibata, Shinobu Ishigaki, Yasunori Kurosawa, Miwa Asahara, Nami Hatayama, Yasuo Ono, C.J. Okumura, Masataka Nakagawa, Yoshinori Sato, Satoshi Nishida, Hisayo Shimizu, Toshiaki Maruyama, Teruo Akuta, Yuki Ouchi, Yu Nakajima
Publikováno v:
International journal of biological macromolecules. 185
Infections of CTX-M extended-spectrum β-lactamase-producing Enterobacterales are a severe threat in clinical settings. CTX-M genes on plasmids have been transferred to many Enterobacterales species, and these species have spread, leading to the glob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0b239664786475953d35059872fd705
https://pubmed.ncbi.nlm.nih.gov/34129888
https://pubmed.ncbi.nlm.nih.gov/34129888
Autor:
C.J. Okumura, Jose M. M. Caaveiro, Kouhei Tsumoto, Daisuke Kuroda, Makoto Nakakido, Kevin C. Entzminger, Misaki Ishii, Toshiaki Maruyama
Publikováno v:
The Journal of Biological Chemistry
Proteins are modulated by a variety of posttranslational modifications including methylation. Despite its importance, the majority of protein methylation modifications discovered by mass spectrometric analyses are functionally uncharacterized, partly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::529889bf127773dbad3788d11cb98087
http://europepmc.org/articles/PMC7948472
http://europepmc.org/articles/PMC7948472
Autor:
Tsutomu Arakawa, C.J. Okumura, Yasunori Kurosawa, Cynthia Li, Teruo Akuta, Takashi Shibata, Toshiaki Maruyama, Tomomi Sato, Masataka Nakagawa
Publikováno v:
International journal of biological macromolecules. 151
This study was conducted to evaluate applicability of the previously reported native agarose gel electrophoresis to the analysis of various monoclonal and polyclonal antibodies. Experiments were carried to test the electrophoresis system for characte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3101cfb8e540c09d0e242215b4b5a001
https://pubmed.ncbi.nlm.nih.gov/32084469
https://pubmed.ncbi.nlm.nih.gov/32084469
Autor:
Yoshinori Sato, Takashi Shibata, Teruo Akuta, Yasunori Kurosawa, C.J. Okumura, Yasuo Ono, Yosuke Tanaka, Masataka Nakagawa, Hisayo Shimizu, Keitaro Imaizumi, Toshiaki Maruyama, Nemuri Todaka
Publikováno v:
Protein Expression and Purification. 146:27-33
Rabbit monoclonal antibodies (mAbs) have many advantages over mouse antibodies in biological research and diagnostics applications because they exhibit high affinity and specificity. However, the methods of recombinant rabbit mAb production have not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d812af27b552ce1a32795557ec5529f
https://doi.org/10.1016/j.pep.2018.01.011
https://doi.org/10.1016/j.pep.2018.01.011
Autor:
Toshiaki Maruyama, Raiji Kawade, C.J. Okumura, Hiroki Akiba, Kouhei Tsumoto, Kevin C. Entzminger
Publikováno v:
Protein Engineering, Design and Selection. 31:243-247
Rabbit antibodies show unique structural characteristics in that kappa chains have an inter-domain disulfide bond between the variable and constant domains. Here we characterized this disulfide bond from physicochemical viewpoints both in stability a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb8762e5a4ea4da59f3c46fc6124a9d
https://doi.org/10.1093/protein/gzy008
https://doi.org/10.1093/protein/gzy008