Výsledky vyhledávání - "C.H.J. Verhoeven"

The in Vivo Human Metabolism of Tibolone

Autor: R. M. E. Vos, L. P. C. Delbressine, C.H.J. Verhoeven, S. F. M. Krebbers

Publikováno v: Drug Metabolism and Disposition. 30:106-112

In vivo metabolism of tibolone was studied in three healthy postmenopausal volunteers after daily oral administration of 2.5 mg of tibolone for 5 days and a single dose of 2.5 mg approximately equal 555 kBq of [(14)C]tibolone on day 6. The 0- to 192-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9af9d31a7f6a719bc206af18ea15e49f
https://doi.org/10.1124/dmd.30.2.106

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Excretion and metabolism of desogestrel in healthy postmenopausal women

Autor: Ivonne M.C.M. Rietjens, R.H.M Gloudemans, C.H.J. Verhoeven, J.J van Lier, R.M.E Vos, P. A. M. Peeters, Geny M. M. Groothuis, F.T.M Verheggen

Publikováno v: Journal of Steroid Biochemistry and Molecular Biology 78 (2001)
Journal of Steroid Biochemistry and Molecular Biology, 78, 471-480
Journal of steroid biochemistry and molecular biology, 78(5), 471-480. PERGAMON-ELSEVIER SCIENCE LTD

The metabolism of desogestrel (13-ethyl-11-methylene-18,19-dinor-17 alpha -pregn-4-en-20-yn-17-ol), a progestagen used in oral contraceptives and hormone replacement therapy, was studied in vivo after a single oral administration of 150 mug [C-14]-la

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73d58743737562b6f33773b76afcb64
https://doi.org/10.1016/s0960-0760(01)00124-8

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Characterization and inhibition of human cytochrome P-450 enzymes involved in the in vitro metabolism of mirtazapine

Autor: C.H.J. Verhoeven, R.M.E. Vos, J.J.P. Bogaards

Publikováno v: European Neuropsychopharmacology. 6:S4-63

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fd7af2f567a7444003caa65c70205b2
https://doi.org/10.1016/0924-977x(96)83095-1

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Excretion balance and metabolism of the progestagen Org 30659 in healthy postmenopausal women

Autor: C.H.J. Verhoeven, R.H.M. Gloudemans, Ivonne M.C.M. Rietjens, R.M.E. Vos, Geny M. M. Groothuis

Publikováno v: Journal of Steroid Biochemistry and Molecular Biology 73 (2000)
Journal of Steroid Biochemistry and Molecular Biology, 73, 39-48

Metabolism of Org 30659 ((17alpha)-17-hydroxy-11-methylene-19-norpregna-4, 15-dien-20-yn-3-one), a new potent progestagen currently under clinical development by NV Organon for use in oral contraception and hormone replacement therapy, was studied in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cf941fa72abde952271be57f053d5d1
https://pubmed.ncbi.nlm.nih.gov/10822023

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