Zobrazeno 1 - 10
of 27
pro vyhledávání: '"C.G. Kornfeld"'
Autor:
Xue Lin, Daniel Kreisel, J. Lai, Wenjun Li, Alexander S. Krupnick, S.B. Richardson, Aida Ibricevic, Mark J. Miller, Andrew E. Gelman, Ruben G. Nava, C.G. Kornfeld, Steven L. Brody
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 44:749-754
Activated T lymphocytes are abundant in the airway during lung allograft rejection. Based on respiratory viral studies, it is the current paradigm that T cells cannot divide in the airway, and that their accumulation in the lumen of the respiratory t
Autor:
C.G. Kornfeld, Wenjun Li, Ruben G. Nava, Andrew E. Gelman, Mark J. Miller, J. Lai, Aida Ibricevic, Alexander S. Krupnick, S.B. Richardson, Steven L. Brody, Xue Lin, Daniel Kreisel
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 44:749-754
Activated T lymphocytes are abundant in the airway during lung allograft rejection. Based on respiratory viral studies, it is the current paradigm that T cells cannot divide in the airway, and that their accumulation in the lumen of the respiratory t
Autor:
S.B. Richardson, Alexander S. Krupnick, Daniel Kreisel, C.G. Kornfeld, Chyi-Song Hsieh, Xue Lin, Wenjun Li, Andrew E. Gelman, Seiichiro Sugimoto
Publikováno v:
The Journal of Immunology. 185:3809-3813
The interaction of CD4+ T cells with MHC class II (MHCII)-expressing hematopoietic APCs plays a critical role in both the generation of protective immune responses and maintenance of tolerance in the lung. The functional significance of MHCII express
Autor:
Alexander S. Krupnick, J. Lai, Mikio Okazaki, G. Alexander Patterson, Seiichiro Sugimoto, Daniel Kreisel, Xue Lin, Andrew E. Gelman, Wenjun Li, Joel R. Garbow, C.G. Kornfeld, S.B. Richardson
Publikováno v:
Nature Protocols. 4:86-93
Unlike transplantation of other solid organs, vascularized mouse lung transplantation has only recently been developed. In this protocol, we describe a detailed method for performing a vascularized and aerated mouse orthotopic lung transplant, which
Autor:
Jeremy R. Tietjens, J. Lai, Alexander S. Krupnick, C.G. Kornfeld, Seiichiro Sugimoto, S.B. Richardson, Friederike Kreisel, G. Alexander Patterson, Mikio Okazaki, Andrew E. Gelman, Daniel Kreisel
Publikováno v:
The Journal of Immunology. 180:4754-4762
Acute rejection continues to present a major obstacle to successful lung transplantation. Although CD4+ T lymphocytes are critical for the rejection of some solid organ grafts, the role of CD4+ T cells in the rejection of lung allografts is largely u
Autor:
A.E. Gelman, M. Okazaki, S. Sugimoto, W. Li, C.G. Kornfeld, J. Lai, S.B. Richardson, F.H. Kreisel, H.J. Huang, J.R. Tietjens, B.H. Zinselmeyer, G.A. Patterson, M.J. Miller, A.S. Krupnick, D. Kreisel
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 10(5)
Graft rejection remains a formidable problem contributing to poor outcomes after lung transplantation. Blocking chemokine pathways have yielded promising results in some organ transplant systems. Previous clinical studies have demonstrated upregulati
Autor:
S.B. Richardson, G. Alexander Patterson, Bernd H. Zinselmeyer, John Dempster, Jeremy R. Tietjens, Alexander S. Krupnick, Wenjun Li, C.G. Kornfeld, Seiichiro Sugimoto, Mark J. Miller, Daniel Kreisel, Friederike Kreisel, J. Lai, Mikio Okazaki, Andrew E. Gelman
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 182(7)
It is the prevailing view that adaptive immune responses are initiated in secondary lymphoid organs. Studies using alymphoplastic mice have shown that secondary lymphoid organs are essential to initiate allograft rejection of skin, heart, and small b
Autor:
Andrew E. Gelman, G.A. Patterson, Richard S. Hotchkiss, Mikio Okazaki, Friederike Kreisel, S.B. Richardson, Wenjun Li, Alexander S. Krupnick, Seiichiro Sugimoto, Howard J. Huang, C.G. Kornfeld, J. Lai, Daniel Kreisel
Publikováno v:
Transplantation proceedings. 41(1)
Lung allografts are considered to be more immunogenic than other solid organs. Little is known about the effectiveness of immunosuppressive regimens after lung transplantation. Herein, we describe a novel model of murine vascularized orthotopic lung
Autor:
Jeremy R. Tietjens, Joel R. Garbow, G. Alexander Patterson, Andrew E. Gelman, Howard J. Huang, Mikio Okazaki, C.G. Kornfeld, Alexander S. Krupnick, Aida Ibricevic, Steven L. Brody, J. Lai, S.B. Richardson, Daniel Kreisel
Publikováno v:
American journal of respiratory cell and molecular biology. 37(6)
Lung transplantation remains the only therapeutic option for many patients suffering from end-stage pulmonary disease. Long-term success after lung transplantation is severely limited by the development of bronchiolitis obliterans. The murine heterot
Autor:
C.G. Kornfeld, Alexander S. Krupnick, Howard J. Huang, Daniel Kreisel, Jon H. Ritter, Nitin A. Das, S.B. Richardson, G.A. Patterson, Mikio Okazaki, Andrew E. Gelman, J. Lai
Publikováno v:
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 7(6)
Outcomes after lung transplantation are markedly inferior to those after other solid organ transplants. A better understanding of cellular and molecular mechanisms contributing to lung graft injury will be critical to improve outcomes. Advances in th