Zobrazeno 1 - 10
of 71
pro vyhledávání: '"C.E. Naylor"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Robert W. Evans, Henry K. Bayele, S. Kaila S. Srai, C.E. Naylor, Alpesh Patel, Nick Beaumont, Christopher L. Joannou, Basharut A. Syed, Peter S. N. Rowe
Publikováno v:
Protein Engineering, Design and Selection. 15:205-214
Hephaestin was implicated in mammalian iron homeostasis following its identification as the defective gene in murine sex-linked anaemia. It is a member of the family of copper oxidases that includes mammalian ceruloplasmin, factors V and VIII, yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fe18408f60f9938089448a6c92f21f1
https://doi.org/10.1093/protein/15.3.205
https://doi.org/10.1093/protein/15.3.205
Publikováno v:
Biochemistry. 39:15002-15011
The role of Asp-177 in the His-Asp catalytic dyad of glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides has been investigated by a structural and functional characterization of the D177N mutant enzyme. Its three-dimensional structure ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56831a2358cd56def820927b5557ff7
https://doi.org/10.1021/bi0014608
https://doi.org/10.1021/bi0014608
Autor:
Deborah A. Scopes, M.J. Adams, L. Vandeputte-Rutten, Veronica M.S. Lam, C.E. Naylor, Lucio Luzzatto, S. Gover, Philip J. Mason, S.W.N. Au
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 55:826-834
Recombinant human glucose 6-phosphate dehydrogenase (G6PD) has been crystallized and its structure solved by molecular replacement. Crystals of the natural mutant R459L grow under similar conditions in space groups P212121 and C2221 with eight or fou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19f98f1a986d197b2b69d58854dd705
https://doi.org/10.1107/s0907444999000827
https://doi.org/10.1107/s0907444999000827
Publikováno v:
Biochemistry. 37:2759-2767
The catalytic mechanism of glucose 6-phosphate dehydrogenase from Leuconostoc mesenteroides was investigated by replacing three amino acids, His-240, Asp-177, and His 178, with asparagine, using site-directed mutagenesis. Each of the mutant enzymes w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2066cfeb811f6b55b83d0f14df24550a
https://doi.org/10.1021/bi972069y
https://doi.org/10.1021/bi972069y
Autor:
C.E. Naylor, L. Luzzatto, S. Gover, T. J. Vulliamy, M.J. Adams, José M. Bautista, P.J. Mason, A.K. Basak, P Rowland
Publikováno v:
Scopus-Elsevier
Human glucose 6-phosphate dehydrogenase (G6PD) has a particularly large number of variants resulting from point mutations; some 60 mutations have been sequenced to date. Many variants, some polymorphic, are associated with enzyme deficiency. Certain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03833cb0ab468df9ef1c84ac7dd266e
https://doi.org/10.1182/blood.v87.7.2974.bloodjournal8772974
https://doi.org/10.1182/blood.v87.7.2974.bloodjournal8772974
Autor:
Nora Cronin, Orval A. Bateman, Nicholas H. Keep, Wilbert C. Boelens, Christine Slingsby, Claire Bagnéris, C.E. Naylor
Publikováno v:
Journal of molecular biology. 392(5)
Small heat shock proteins (sHsps) are a family of large and dynamic oligomers highly expressed in long-lived cells of muscle, lens and brain. Several family members are upregulated during stress, and some are strongly cytoprotective. Their polydisper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e63c8be0c8a78aabdccbc805326b96
https://pubmed.ncbi.nlm.nih.gov/19646995
https://pubmed.ncbi.nlm.nih.gov/19646995
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Ali M. Al-Shangiti, Sean P. Nair, Brian Henderson, Benjamin M. Chain, David Briggs, C.E. Naylor
The staphylococcal superantigen-like proteins (SSLs) are a family of polymorphic paralogs encoded in the S taphylococcus aureus genome whose function is unknown. The crystal structure of SSL7 was determined and compared to that of SSL5 and that of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a9f80be771778f84d6e4923cbe94d86
https://europepmc.org/articles/PMC427445/
https://europepmc.org/articles/PMC427445/
Publikováno v:
Acta crystallographica. Section D, Biological crystallography. 57(Pt 5)
The reduced coenzymes NADH and NADPH only differ by one phosphate, but in the cell NADH provides reducing power for catabolism while NADPH is utilized in biosynthetic pathways. Enzymes almost invariably discriminate between the coenzymes, but glucose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4293ea95f83044ee62e474cbffca428
https://pubmed.ncbi.nlm.nih.gov/11320304
https://pubmed.ncbi.nlm.nih.gov/11320304