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Akademický článek

The STEPWISE study: study protocol for a smartphone-based exercise solution for people with Parkinson’s Disease (randomized controlled trial)

Autor: Sabine Schootemeijer, Nienke M. de Vries, Eric A. Macklin, Kit C.B. Roes, Hilde Joosten, Larsson Omberg, Alberto Ascherio, Michael A. Schwarzschild, Bastiaan R. Bloem

Publikováno v: BMC Neurology, Vol 23, Iss 1, Pp 1-13 (2023)

Abstract Background Exercise has various health benefits for people with Parkinson’s disease (PD). However, implementing exercise into daily life and long-term adherence remain challenging. To increase a sustainable engagement with physical activit

Externí odkaz: https://doaj.org/article/d24b24c9ffe94219a39c40a3949d4aeb

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Akademický článek

Flexible modelling of risk factors on the incidence of pneumonia in young children in South Africa using piece-wise exponential additive mixed modelling

Autor: Jordache Ramjith, Kit C.B. Roes, Heather J. Zar, Marianne A. Jonker

Publikováno v: BMC Medical Research Methodology, Vol 21, Iss 1, Pp 1-13 (2021)

Abstract Introduction Recurrent episodes of pneumonia are frequently modeled using extensions of the Cox proportional hazards model with the underlying assumption of time-constant relative risks measured by the hazard ratio. We aim to relax this assu

Externí odkaz: https://doaj.org/article/981945ada8f246698f2260d8994ee451

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Akademický článek

Interval estimation of the overall treatment effect in a meta-analysis of a few small studies with zero events

Autor: Konstantinos Pateras, Stavros Nikolakopoulos, Dimitris Mavridis, Kit C.B. Roes

Publikováno v: Contemporary Clinical Trials Communications, Vol 9, Iss C, Pp 98-107 (2018)

When a meta-analysis consists of a few small trials that report zero events, accounting for heterogeneity in the (interval) estimation of the overall effect is challenging. Typically, we predefine meta-analytical methods to be employed. In practice,

Externí odkaz: https://doaj.org/article/0bc5de98cef1435eb53483e94aa0731f

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Akademický článek

Predicting enrollment performance of investigational centers in phase III multi-center clinical trials

Autor: Rutger M. van den Bor, Diederick E. Grobbee, Bas J. Oosterman, Petrus W.J. Vaessen, Kit C.B. Roes

Publikováno v: Contemporary Clinical Trials Communications, Vol 7, Iss , Pp 208-216 (2017)

Failure to meet subject recruitment targets in clinical trials continues to be a widespread problem with potentially serious scientific, logistical, financial and ethical consequences. On the operational level, enrollment-related issues may be mitiga

Externí odkaz: https://doaj.org/article/1ea29a474bec430685ab0c67821948db

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Akademický článek

Validation of multisource electronic health record data: an application to blood transfusion data

Autor: Loan R. van Hoeven, Martine C. de Bruijne, Peter F. Kemper, Maria M.W. Koopman, Jan M.M. Rondeel, Anja Leyte, Hendrik Koffijberg, Mart P. Janssen, Kit C.B. Roes

Publikováno v: BMC Medical Informatics and Decision Making, Vol 17, Iss 1, Pp 1-10 (2017)

Abstract Background Although data from electronic health records (EHR) are often used for research purposes, systematic validation of these data prior to their use is not standard practice. Existing validation frameworks discuss validity concepts wit

Externí odkaz: https://doaj.org/article/a19b8a79534f435c88d9280b1ef87c83

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Joint modeling of endpoints can be used to answer various research questions in randomized clinical trials

Autor: Ruben P.A. van Eijk, Kit C.B. Roes, Leonard H. van den Berg, Ying Lu

Publikováno v: Journal of Clinical Epidemiology, 147, pp. 32-39
J Clin Epidemiol
Journal of Clinical Epidemiology, 147, 32-39

OBJECTIVE: Correlated longitudinal and time-to-event outcomes, such as the rate of cognitive decline and the onset of Alzheimer’s disease, are frequent (co-)primary and key secondary endpoints in randomized clinical trials (RCTs). Despite their bio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e1c35fa83871f062ef8664ad1b9c6bc
https://doi.org/10.1016/j.jclinepi.2022.03.009

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Gender differences in the response to antipsychotic medication in patients with schizophrenia: An individual patient data meta-analysis of placebo-controlled studies

Autor: Bram W.C. Storosum, Taina Mattila, Tamar D. Wohlfarth, Christine C. Gispen-de Wied, Kit C.B. Roes, Wim van den Brink, Lieuwe de Haan, Damiaan A.J.P. Denys, Jasper B. Zantvoord

Publikováno v: Psychiatry research, 320. Elsevier Ireland Ltd
Psychiatry Research, 320
Psychiatry research, 320:114997. Elsevier Ireland Ltd

Contains fulltext : 291389.pdf (Publisher’s version ) (Open Access) OBJECTIVE: To determine whether gender and menopausal status moderate the response to antipsychotic medication in patients with schizophrenia. METHODS: We analyzed data of 22 short

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b9e87144925089575d8f46721c207bb
https://pure.knaw.nl/portal/en/publications/a58eae0c-484c-4225-9cc3-2785050a4d15

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Use of Non-concurrent Common Control in Master Protocols in Oncology Trials: Report of an American Statistical Association Biopharmaceutical Section Open Forum Discussion

Autor: Qi Jiang, Rajeshwari Sridhara, Thomas E. Gwise, Martin Posch, Cindy Lu, Richard Simon, Andrew Raven, Mary W. Redman, Lorenzo Hess, Yuan Li Shen, Kit C.B. Roes, R. Pazdur, Olga Marchenko, Yuan Ji, Scott Berry, Marc R. Theoret, Khadija Rantell

This article summarizes the discussions from the American Statistical Association (ASA) Biopharmaceutical (BIOP) Section Open Forum that took place on December 10, 2020 and was organized by the ASA BIOP Statistical Methods in Oncology Scientific Work

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25161fc0c4b7915310fa069224e2a3ee
http://arxiv.org/abs/2209.09173

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Systematic Review of N-of-1 Studies in Rare Genetic Neurodevelopmental Disorders

Autor: Marion M.M.G. Brands, Annelieke R. Müller, Joost G. Daams, Agnies M. van Eeghen, Clara D.M. van Karnebeek, Frits A. Wijburg, Peter M. van de Ven, Martina C. Cornel, Erik Boot, Kit C.B. Roes

Publikováno v: Neurology, 96, 529-540
Neurology, 96(11), 529-540. Lippincott Williams and Wilkins
Müller, A R, Brands, M M, van de Ven, P M, Roes, K C, Cornel, M C, van Karnebeek, C D, Wijburg, F A, Daams, J G, Boot, E & van Eeghen, A M 2021, ' Systematic Review of N-of-1 Studies in Rare Genetic Neurodevelopmental Disorders : The Power of 1 ', Neurology, vol. 96, no. 11, pp. 529-540 . https://doi.org/10.1212/WNL.0000000000011597
Neurology, 96, 11, pp. 529-540

ObjectiveTo improve the use of N-of-1 studies in rare genetic neurodevelopmental disorders, we systematically reviewed the literature and formulated recommendations for future studies.MethodsThe systematic review protocol was registered in the PROSPE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::314a6f24bd1ae057d955fbc731462e6f
http://www.scopus.com/inward/record.url?scp=85102964228&partnerID=8YFLogxK

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