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pro vyhledávání: '"C.A. Rizzi"'
Akademický článek
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Akademický článek
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Autor:
Ivarne L.S. Tersariol, Claudia C.A. Rizzi, Iseli L. Nantes, Boris Turk, Ivica Stefe, Luiz Juliano, Helena B. Nader, Fabio D. Nascimento, Adriana K. Carmona
Publikováno v:
Archives of Biochemistry and Biophysics. 436:323-332
Glycosaminoglycans have been shown to be important regulators of activity of several papain-like cathepsins. Binding of glycosaminoglycans to cathepsins thus directly affects catalytic activity, stability or the rate of autocatalytic activation of ca
Autor:
Eliana Messori, Adele Lucchelli, Marcello Tonini, B. Balestra, Stefano M. Candura, C.A. Rizzi
Publikováno v:
British Journal of Pharmacology. 115:677-683
1. In isolated detrusor strips from the guinea-pig urinary bladder, contractile responses to electrical field stimulation were mostly mediated by neurally released acetylcholine (ACh) and adenosine 5'-triphosphate (ATP). 2. 5-Hydroxytryptamine (5-HT)
Publikováno v:
Pharmacological Research. 31:257-260
Drugs interacting with serotonin (5-hydroxytryptamine, 5-HT) receptors are of value in the treatment of several gastrointestinal disturbances. Selective 5-HT3 receptor antagonists (ondansetron, granisetron, tropisetron) are widely utilized to control
Autor:
C.A. Rizzi, Herbert Ladinsky, Schiantarelli Pierino, Arturo Donetti, A Schiavone, Giovanni Battista Schiavi, Angelo Sagrada, Raffaele Cesana
Publikováno v:
Naunyn-Schmiedeberg’s Archives of Pharmacology. 349:338-345
We have investigated the in vivo motor stimulating and gastroprokinetic properties of the azabicycloalkyl benzimidazolone derivative BIMU 1 (3-ethyl-2,3-dihydro-N-(8-methyl-8-azabicyclo[3.2.1]oct-3-yl)-2-oxo-1H- benzimidazole-1-carboxamide hydrochlor
Autor:
Li, Yaocun1 (AUTHOR) yli47@qub.ac.uk, Vora, Lalitkumar K.1 (AUTHOR), Wang, Jiawen1 (AUTHOR), Sabri, Akmal Hidayat Bin1 (AUTHOR), Graham, Andrew1 (AUTHOR), McCarthy, Helen O.1 (AUTHOR), Donnelly, Ryan F.1 (AUTHOR) r.donnelly@qub.ac.uk
Publikováno v:
Pharmaceutics. May2024, Vol. 16 Issue 5, p676. 15p.
Autor:
C.A. Rizzi, Giovanni Battista Schiavi, Giorgio Moro, Ugo Cosentino, Ettore Giraldo, Myrna Gil Quintero, Marco Turconi
Publikováno v:
Journal of Molecular Structure: THEOCHEM. 286:275-291
The conformational and electronic properties of 11 5-HT 3 receptor antagonists, were investigated to rationalize their biological activity. All compounds fulfill the previously reported geometrical requirements for the pharmacophore, although they sh
Autor:
Roberta Termini, Roberto Maria Scarpa, C.A. Rizzi, Silvano Berioli, Domenico Prezioso, S. Viaggi, Filiberto Zattoni
Publikováno v:
European Urology. 40:2-4
Objective: Few epidemiological studies are available on Italian patients with lower urinary tract symptoms and their QoL. QUIBUS (QUality of life Investigated in BPH patients with Urinary Symptoms) is an observational longitudinal study aimed at eval
Autor:
Arturo Donetti, Antonio Schiavone, Rosella Micheletti, Marco Turconi, Massimo Nicola, Ernesto Montagna, Raffaele Cesana, Angelo Sagrada, C.A. Rizzi
Publikováno v:
European Journal of Pharmacology. 203:203-211
The pharmacological profile of six representative members of a novel class of 5-HT3 receptor antagonists is described. The compounds are esters and amides of benzimidazolone-1-carboxylic acid with a basic azabicycloalkyl moiety (compounds 1-3) and th