Zobrazeno 1 - 10
of 32
pro vyhledávání: '"C.A. Korduba"'
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 730:55-59
A simple and sensitive high-performance liquid chromatographic (HPLC) method was developed for the determination of SCH 27899, an everninomycin antibiotic, in rat plasma. The method involved plasma protein precipitation with acetonitrile, followed by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::905dcf868d6ff26acb46da070ddca9d1
https://doi.org/10.1016/s0378-4347(99)00204-2
https://doi.org/10.1016/s0378-4347(99)00204-2
Publikováno v:
Chemotherapy. 43:86-93
The pharmacokinetics of isepamicin, a broad-spectrum aminoglycoside antibiotic, was studied in man after intramuscular administration. Two groups each of 6 volunteers received isepamicin for 10 consecutive days by intramuscular injection at respectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bae035abc72adcc5406e740c5f70d5f
https://doi.org/10.1159/000239541
https://doi.org/10.1159/000239541
Autor:
C.A. Korduba, Amin A. Nomeir, Chin-Chung Lin, Melton B. Affrime, Mitchell N. Cayen, David L. Cutler, Vijay Batra, Elaine Radwanski
Publikováno v:
Antimicrobial Agents and Chemotherapy. 41:1794-1796
The pharmacokinetics of isepamicin following administration of a 1-g dose were evaluated for 18 healthy male volunteers between the ages of 26 and 38. In a randomized crossover fashion, each volunteer received doses of isepamicin by a 30-min intraven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dac81706bdf018bbc09f694f05440bc2
https://doi.org/10.1128/aac.41.8.1794
https://doi.org/10.1128/aac.41.8.1794
Publikováno v:
Therapeutic drug monitoring. 19(6)
Plasma concentrations of isepamicin, a new aminoglycoside antibiotic, were determined by radioimmunoassay (RIA), microbiological assay (MA), and high-performance liquid chromatography (HPLC) in healthy volunteers after administration of 7.5 mg/kg int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eabe01c05b9f0e4c7570dbe0c2cfd422
https://pubmed.ncbi.nlm.nih.gov/9421110
https://pubmed.ncbi.nlm.nih.gov/9421110
The pharmacokinetics of isepamicin, a broad-spectrum aminoglycoside antibiotic, were studied in men after intravenous administration. Three groups of six volunteers received isepamicin for 10 consecutive days by 0.5-h intravenous infusions at respect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7933c315481a4d98b726e9d40c30b2e
https://europepmc.org/articles/PMC163028/
https://europepmc.org/articles/PMC163028/
Autor:
M Affrime, Chin-Chung Lin, C.A. Korduba, Amin A. Nomeir, Elaine Radwanski, D Cutler, Vijay Batra, Mitchell N. Cayen
Twelve healthy adult male volunteers received 1 g (base equivalent) of 14C-isepamicin (131 microCi) as an intravenous bolus over 5 min. The areas under the plasma concentration-time curves at infinity for isepamicin (196 micrograms*h/ml) and total ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0db3431507382ceedf99f973900a121
https://europepmc.org/articles/PMC162914/
https://europepmc.org/articles/PMC162914/
Autor:
E. M. Oden, George H. Miller, R. D'Souza, Menger Chung, Chin-Chung Lin, Samson Symchowicz, Hong-Ki Kim, J. Veals, C.A. Korduba, Eugene L. Moss, David Loebenberg, Josephine Lim
Publikováno v:
Journal of Antimicrobial Chemotherapy. 15:219-226
The pharmacokinetics of 14C-Sch 34343 were studied in rats and dogs following intravenous and intramuscular dosing. In both species, it was rapidly absorbed after intramuscular dosing. The serum AUC for total radioactivity and for intact drug after i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c42a44a6a9f75822f5a77ee0222084f4
https://doi.org/10.1093/jac/15.suppl_c.219
https://doi.org/10.1093/jac/15.suppl_c.219
Publikováno v:
European Journal of Pharmacology. 41:291-299
Chronic (6 days) dexamethasone administration caused a slight decrease of rat brain MAO enzyme activity which was reflected by lower levels of 14C-homovanillic acid (HVA) and increased levels of 14C-3-methoxytyramine (3MT) following intracisternal in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87b6301a672dbd1fbca8f49e5b690fd9
https://doi.org/10.1016/0014-2999(77)90322-3
https://doi.org/10.1016/0014-2999(77)90322-3
Autor:
C.A. Korduba, Samson Symchowicz
Publikováno v:
Biochemical Pharmacology. 16:385-391
The metabolism of dopamine-14C was investigated in selected organs of the rat and mouse, by means of a new, rapid, and quantitative assay of tissue catecholamines. Differences were found in the rate of dopamine metabolism in organs of the same specie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa5b4332b881b8d591145f81eff85725
https://doi.org/10.1016/0006-2952(67)90039-1
https://doi.org/10.1016/0006-2952(67)90039-1
The effect of pheniramine and its structural analogues on 5-hydroxytryptamine in rat and mouse brain
Publikováno v:
Life Sciences. 13:1557-1564
A series of pheniramine analogues was tested for the ability to inhibit 5-HT uptake by synaptosomes of rat corpus striatum. A chlorine or bromine substitution on the aromatic ring greatly facilitated the inhibitory activity of pheniramine. 3,4-dichlo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e95669ba8f0a7ba4b96d7d88028d20d
https://doi.org/10.1016/0024-3205(73)90144-6
https://doi.org/10.1016/0024-3205(73)90144-6