Zobrazeno 1 - 10
of 5 799
pro vyhledávání: '"C.-S. Lee"'
Publikováno v:
Atmospheric Measurement Techniques, Vol 8, Iss 6, Pp 2531-2542 (2015)
In this paper, we perform a systematic evaluation of the impact of Global Positioning System radio occultation (GPSRO) data on typhoon-track prediction over the northwestern Pacific. Specifically, we perform data assimilation and forecast experiments
Externí odkaz:
https://doaj.org/article/71fd406cce81477f9ce0fc4ffa1ec298
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 13, Iss 1, Pp 65-74 (2013)
This study is focused on the modification of a typhoon rainfall climatological model, by using the dataset up to 2006 and including data collected from rain gauge stations established after the 921 earthquake (1999). Subsequently, the climatology rai
Externí odkaz:
https://doaj.org/article/4183bd2ed91f4f77bbcd7580cac7cc26
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 8, Iss 6, Pp 1463-1474 (2008)
Due to the Central Mountain Range with an elevation up to about 4 km, the amount and distribution of rainfall in Taiwan associated with typhoons or tropical cyclones (TCs) depends not only on the distribution of convection within the TCs (internal st
Externí odkaz:
https://doaj.org/article/502751c4739a489bb419ba0cde21f3d2
Autor:
Stanley C. Xie, Yinuo Wang, Craig J. Morton, Riley D. Metcalfe, Con Dogovski, Charisse Flerida A. Pasaje, Elyse Dunn, Madeline R. Luth, Krittikorn Kumpornsin, Eva S. Istvan, Joon Sung Park, Kate J. Fairhurst, Nutpakal Ketprasit, Tomas Yeo, Okan Yildirim, Mathamsanqa N. Bhebhe, Dana M. Klug, Peter J. Rutledge, Luiz C. Godoy, Sumanta Dey, Mariana Laureano De Souza, Jair L. Siqueira-Neto, Yawei Du, Tanya Puhalovich, Mona Amini, Gerry Shami, Duangkamon Loesbanluechai, Shuai Nie, Nicholas Williamson, Gouranga P. Jana, Bikash C. Maity, Patrick Thomson, Thomas Foley, Derek S. Tan, Jacquin C. Niles, Byung Woo Han, Daniel E. Goldberg, Jeremy Burrows, David A. Fidock, Marcus C. S. Lee, Elizabeth A. Winzeler, Michael D. W. Griffin, Matthew H. Todd, Leann Tilley
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Malaria poses an enormous threat to human health. With ever increasing resistance to currently deployed drugs, breakthrough compounds with novel mechanisms of action are urgently needed. Here, we explore pyrimidine-based sulfonamides as a ne
Externí odkaz:
https://doaj.org/article/74ceb3d2587846d1a75544faccf7d8f1
Autor:
Eva Stadler, Mohamed Maiga, Lukas Friedrich, Vandana Thathy, Claudia Demarta-Gatsi, Antoine Dara, Fanta Sogore, Josefine Striepen, Claude Oeuvray, Abdoulaye A. Djimdé, Marcus C. S. Lee, Laurent Dembélé, David A. Fidock, David S. Khoury, Thomas Spangenberg
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract We report an analysis of the propensity of the antimalarial agent cabamiquine, a Plasmodium-specific eukaryotic elongation factor 2 inhibitor, to select for resistant Plasmodium falciparum parasites. Through in vitro studies of laboratory st
Externí odkaz:
https://doaj.org/article/fc7d61999951431e86b5f6942e16ac55
Publikováno v:
Endocrines, Vol 4, Iss 3, Pp 558-572 (2023)
Background: The prevalence of thyroid disease has seen a rapid increase in recent times, primarily attributed to the fast pace of lifestyles that often result in poor dietary choices, work-life imbalances, social stress, genetic mutations, and improv
Externí odkaz:
https://doaj.org/article/a2eb289c74894e4f845a5e933753abd0
Autor:
Krittikorn Kümpornsin, Theerarat Kochakarn, Tomas Yeo, John Okombo, Madeline R. Luth, Johanna Hoshizaki, Mukul Rawat, Richard D. Pearson, Kyra A. Schindler, Sachel Mok, Heekuk Park, Anne-Catrin Uhlemann, Gouranga P. Jana, Bikash C. Maity, Benoît Laleu, Elodie Chenu, James Duffy, Sonia Moliner Cubel, Virginia Franco, Maria G. Gomez-Lorenzo, Francisco Javier Gamo, Elizabeth A. Winzeler, David A. Fidock, Thanat Chookajorn, Marcus C. S. Lee
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract In vitro evolution of drug resistance is a powerful approach for identifying antimalarial targets, however, key obstacles to eliciting resistance are the parasite inoculum size and mutation rate. Here we sought to increase parasite genetic d
Externí odkaz:
https://doaj.org/article/cd0bb7acaa454eeba503bf34e9f1ecc8
Autor:
Johanna Hoshizaki, Sophie H. Adjalley, Vandana Thathy, Kim Judge, Matthew Berriman, Adam J. Reid, Marcus C. S. Lee
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-6 (2023)
Externí odkaz:
https://doaj.org/article/8c60c21f7b9446a48dac410225f0927c
Autor:
H. A. Haridhi, B. S. Huang, K. L. Wen, A. Mirza, S. Rizal, S. Purnawan, I. Fajri, F. Klingelhoefer, C. S. Liu, C. S. Lee, C. R. Wilson, T.-R. Wu, I. Setiawan, V. B. Phung
Publikováno v:
Natural Hazards and Earth System Sciences, Vol 23, Pp 507-523 (2023)
Near the northern border of Sumatra, the right-lateral strike–slip Sumatran fault zone splits into two branches and extends into the offshore, as revealed by seismic sounding surveys. However, due to its strike–slip faulting characteristics, the
Externí odkaz:
https://doaj.org/article/d98ebe59f7324dc4b0747f8fd34c8f51
Autor:
Johanna Hoshizaki, Sophie H. Adjalley, Vandana Thathy, Kim Judge, Matthew Berriman, Adam J. Reid, Marcus C. S. Lee
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Important regulation occurs at the level of transcription in Plasmodium falciparum and growing evidence suggests that these apicomplexan parasites have complex regulatory networks. Recent studies implicate long noncoding RNAs (lnc
Externí odkaz:
https://doaj.org/article/e96b697c12f34df39580518217d21807