Zobrazeno 1 - 10
of 32 926
pro vyhledávání: '"C.-ELEGANS"'
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 102-112 (2024)
The Cell Division Cycle and Apoptosis Regulator (CCAR) protein family members have recently emerged as regulators of alternative splicing and transcription, as well as having other key physiological functions. For example, mammalian CCAR2/DBC1 forms
Externí odkaz:
https://doaj.org/article/f05f73d8f2c248f9a36a420d602f3ff2
Publikováno v:
RNA Biology, Vol 21, Iss 1, Pp 449-458 (2024)
Transgene silencing is a common phenomenon observed in Caenorhabditis elegans, particularly in the germline, but the precise mechanisms underlying this process remain elusive. Through an analysis of the transcription factors profile of C. elegans, we
Externí odkaz:
https://doaj.org/article/c149a1698de14bbba6bd5cd90d2e12ae
Autor:
Karthick Raja Arulprakasam, Janelle Wing Shan Toh, Herman Foo, Mani R. Kumar, An-Nikol Kutevska, Emilia Emmanuelle Davey, Marek Mutwil, Guillaume Thibault
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-12 (2024)
Abstract In the rapidly expanding domain of scientific research, tracking and synthesizing information from the rapidly increasing volume of publications pose significant challenges. To address this, we introduce a novel high-throughput pipeline that
Externí odkaz:
https://doaj.org/article/d45013f698b544b6b5b8d16ab2943bc8
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-15 (2024)
Abstract Understanding the syntenic relationships among genomes is crucial to elucidate the genomic mechanisms that drive the evolution of species. The nematode Caenorhabditis is a good model for studying genomic evolution due to the well-established
Externí odkaz:
https://doaj.org/article/07787f2f18fe4ff58eb46a8bd6c47f4a
Autor:
Luca Golinelli, Ellen Geens, Allister Irvine, Ciaran J. McCoy, Elke Vandewyer, Louise E. Atkinson, Angela Mousley, Liesbet Temmerman, Isabel Beets
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-21 (2024)
Abstract Background The phylum Nematoda is incredibly diverse and includes many parasites of humans, livestock, and plants. Peptide-activated G protein-coupled receptors (GPCRs) are central to the regulation of physiology and numerous behaviors, and
Externí odkaz:
https://doaj.org/article/c2d670455c1b439c9fcacc8998ab993e
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract 2K4L is a rationally designed analog of the short α-helical peptide temporin-1CEc, a natural peptide isolated and purified from the skin secretions of the Chinese brown frog Rana chensinensis by substituting amino acid residues. 2K4L displa
Externí odkaz:
https://doaj.org/article/3e302973277b434dbee0bc1785959e39
Autor:
Wenfeng Li, Shuming Chen, Jing Lang, Jing Luo, Jiahui Chen, Liping Zhang, Zhijie Sun, Deli Dong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 7, Pp 3266-3280 (2024)
The drugs extending healthspan in clinic have always been searched. Nitazoxanide is an FDA-approved clinical antiprotozoal drug. Nitazoxanide is rapidly metabolized to tizoxanide after absorption in vivo. Our previous studies find that nitazoxanide a
Externí odkaz:
https://doaj.org/article/a97e426a84d445f1b4e36333464de582
Autor:
Feng Xue, Martina Ragno, Sarah A. Blackburn, Michael Fasseas, Sushmita Maitra, Mingzhi Liang, Subash Rai, Giulia Mastroianni, Frederique Tholozan, Rachel Thompson, Laura Sellars, Rebecca Hall, Chris Saunter, David Weinkove, Marina Ezcurra
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
IntroductionAntimicrobial resistance is a growing health problem. Pseudomonas aeruginosa is a pathogen of major concern because of its multidrug resistance and global threat, especially in health-care settings. The pathogenesis and drug resistance of
Externí odkaz:
https://doaj.org/article/46d67608618f48899b38842b0f035f06