Zobrazeno 1 - 10
of 175
pro vyhledávání: '"C. von Eichel-Streiber"'
Autor:
Wolfgang Witte, M. Neumann, Tim Eckmanns, Bernhard Bornhofen, Andreas Jansen, C. von Eichel-Streiber, B. Weiß, Manfred Kist, H. Michels, Henning Zaiß, Niels Kleinkauf
Publikováno v:
Zeitschrift für Gastroenterologie. 48:1120-1125
Introduction: In September 2007 an increase of severe Clostridium difficile-associated infections (CDI) was noticed in a hospital in the city of Trier, Germany. It was assumed that a new, possibly hypervirulent strain (PCR ribotype 027) was related t
Autor:
Charles A. Parkos, Paul Verkade, Asma Nusrat, J. R. Turner, C. von Eichel-Streiber, James L. Madara
Publikováno v:
Infection and Immunity. 69:1329-1336
The anaerobic bacterium Clostridium difficile is the etiologic agent of pseudomembranous colitis. C. difficile toxins TcdA and TcdB are UDP-glucosyltransferases that monoglucosylate and thereby inactivate the Rho family of GTPases (W. P. Ciesla, Jr.,
Autor:
C von Eichel-Streiber
Publikováno v:
FEMS Microbiology Letters. 178:163-168
Autor:
F. Soehn, Veit Braun, Petra Leukel, A. Wagenknecht-Wiesner, Manfred Weidmann, M. Kohl, C. von Eichel-Streiber
Publikováno v:
ResearcherID
The pathogenicity locus (PaLoc) of Clostridium difficile isolate 8864 was investigated to locate genetic rearrangements that would explain the exceptional pathogenicity of this particular isolate. Two major changes were defined: an insertion of 1.1 k
Autor:
Robbert H. Cool, M. Thiel, J de Gunzburg, E. Tapp, B. Bauer, A. Grannass, Matthias Voss, C. von Eichel-Streiber, Martina Schmidt, Karl Jakobs
Publikováno v:
Journal of Biological Chemistry. 273:7413-7422
Activation of m3 muscarinic acetylcholine receptor (mAChR), stably expressed in human embryonic kidney (HEK)-293 cells, leads to phospholipase D (PLD) stimulation, a process apparently involving Rho GTPases, as shown by studies with Clostridium botul
Autor:
S. Tannert-Otto, Matthias Krüll, Norbert Suttorp, Klaus Aktories, N. Vollrath, Stefan Hippenstiel, I. Just, C. von Eichel-Streiber
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 272:L38-L43
The endothelial cytoskeleton is important for the regulation of endothelial barrier function. Small GTP-binding Rho proteins play a central role in the organization of the microfilament system. Clostridium difficile toxin B (TcdB) inactivates Rho pro
Publikováno v:
Journal of Crystal Growth. 170:783-787
The three semiconductors InAs, InPSb and GaSb were grown using low-pressure MOVPE. InAs and InPSb were deposited on InAs while GaSb was deposited on GaSb substrates. The optical and electrical properties of layers with thicknesses between 1 and 2 μm
Publikováno v:
Molecular Microbiology. 17:313-321
Strain 1470 is the standard typing strain for serogroup F of Clostridium difficile containing both toxin genes, toxA-1470 and toxB-1470. A polymerase chain reaction (PCR)-based approach to the sequencing of the total toxB-1470 gene identified an open
Publikováno v:
Journal of Clinical Investigation. 95:1026-1031
Enterotoxin A is one of the major virulence factors of Clostridium difficile, and the causative agent of antibiotic-associated pseudomembranous colitis. In cell culture (NIH-3T3, rat basophilic leukemia cells) toxin A inhibits Clostridium botulinum A
Publikováno v:
Journal of Cell Science. 107:1653-1659
Clostridium difficile toxin B and Clostridium botulinum C3 exoenzyme caused comparable morphological alteration of CHO cells, which was accompanied by disaggregation of the microfilamental cytoskeleton. The cytotoxic effect of toxin B was correlated