Renal Clearance of Temocillin in Volunteers1

Autor: Herman Mattie, D. Overbosch, C. van Gulpen

Publikováno v: Drugs. 29:128-134

After administration of a loading dose, temocillin was infused intravenously into 5 volunteers for 3 hours (250 and 750 mg/h). A urine flow of more than 500 ml/h was maintained. The mean plasma concentrations were 131.4 and 220.7 mg/L during the lowe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcaa04077e4be8dc358d1381924f7f31
https://doi.org/10.2165/00003495-198500295-00027

Abstracts of papers clinical pharmacological meeting

Autor: F. A. van den Ouweland, P. C. Eenhoorn, Y. Tan, F. W. J. Gribnau, A. van Brupgen, P. A. de Graeff, E. W. van den Toren, W. H. van Gilst, H. Wesseling, K. I. Lie, C. T. Postula, W. B. L. Hoefnagels, Th. de Boo, Th. Thien, E. S. Boon, C. G. Goyskes, P. Boor, B. A. M. van Schalk, C. Abma, T. R. J. A. Frijns, J. Wamer, L. D. Elving, E. de Nobel, H. Mattie, C. van Gulpen, J-W. J. Lammers, P. Minette, P. J. Barnes, R. C. Jongejan, J. C. de Jongste, H. C. Raatgeep, I. L. Bonta, K. F. Kerrebijn, M. J. Mol, A. F. Stalenhoef, P. M. Stuyt, A. van 't Laar, A. A. M. Ermens, M. Schoester, J. Lindemans, J. Abels, M. A. van Baak, J. M. V. Mooij, P. M. H. Schiffers, J. F. M. Wetzels, J. D. v. Berqeyk, F. H. J. A. v. Heusden, F. Th. M. Huysmans, A. J. Hoitsma, R. A. P. Koene, H. M. L. Jansen, F. G. M. Russel, A. C. Wouterse, C. A. M. van Ginneken, Y. W. A. v. d. Pol, E. G. E. de Vries, J. Greidanus, N. H. Mulder, D. Th. Sleijfer, P. H. B. Willemse, D. R. A. Uges, P. A. B. M. Smits, J. W. Louwerenburg, J. H. Kingma, F. N. IJdenberg, F. G. J. Poelma, R. Breŝ, J. J. Tukker, H. P. Remmert, M. Olling, W. Slob, W. van der Giesen, A. G. Rauws, E. A. Runhaar, J. P. Neijt, J. J. M. Holthuis, D. de Vos, J J Tukker, F G J Poelma, H. H. W. Thijssen, K. Hamulyák, C. Franssen, H. Wollersheim, R. W. M. M. Jansen, H. J. J. van Lier, W. H. L. Hoefnagels, C. Grgen, M-A. Horan, Z. A. R. Oomerjee, D. D. Breimer, C. F. A. van Bezooijen, H. J. Keizer, F. J. Cleton, E. A. de Bruijn, U. R. Tiaden, A. de Boer, J. C. J. Stiekema, M. Danhof

Publikováno v: Pharmaceutisch Weekblad. 10:178-184

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2b9f9514cb9f26f9956005c8dcb5f7f
https://doi.org/10.1007/bf01959428

Pharmacokinetics of vibunazole (Bay n7133) administered orally to healthy subjects

Autor: J. M. van der Meer, Herman Mattie, O. Kelder, C. van Gulpen, J.W. van 't Wout

Publikováno v: Journal of Antimicrobial Chemotherapy, 16, 75-79
Journal of Antimicrobial Chemotherapy, 16, 1, pp. 75-79

The role of gastric acidity in the absorption of the new antifungal drug vibunazole was studied in six healthy volunteers. Vibunazole was administered orally as 400 mg tablets to fasting subjects under three conditions: after 400 mg cimetidine orally

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498c5e66385db3a155c072cdeee09a57
http://hdl.handle.net/2066/14779

Renal clearance of temocillin in volunteers

Autor: D, Overbosch, C, van Gulpen, H, Mattie

Publikováno v: Drugs. 29

After administration of a loading dose, temocillin was infused intravenously into 5 volunteers for 3 hours (250 and 750 mg/h). A urine flow of more than 500 ml/h was maintained. The mean plasma concentrations were 131.4 and 220.7 mg/L during the lowe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9ec9d53ecf3fbe6a43e7cbc82f898770
https://pubmed.ncbi.nlm.nih.gov/4029016

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