Renal Clearance of Temocillin in Volunteers1

Autor: Herman Mattie, D. Overbosch, C. van Gulpen

Publikováno v: Drugs. 29:128-134

After administration of a loading dose, temocillin was infused intravenously into 5 volunteers for 3 hours (250 and 750 mg/h). A urine flow of more than 500 ml/h was maintained. The mean plasma concentrations were 131.4 and 220.7 mg/L during the lowe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dcaa04077e4be8dc358d1381924f7f31
https://doi.org/10.2165/00003495-198500295-00027

Abstracts of papers clinical pharmacological meeting

Autor: F. A. van den Ouweland, P. C. Eenhoorn, Y. Tan, F. W. J. Gribnau, A. van Brupgen, P. A. de Graeff, E. W. van den Toren, W. H. van Gilst, H. Wesseling, K. I. Lie, C. T. Postula, W. B. L. Hoefnagels, Th. de Boo, Th. Thien, E. S. Boon, C. G. Goyskes, P. Boor, B. A. M. van Schalk, C. Abma, T. R. J. A. Frijns, J. Wamer, L. D. Elving, E. de Nobel, H. Mattie, C. van Gulpen, J-W. J. Lammers, P. Minette, P. J. Barnes, R. C. Jongejan, J. C. de Jongste, H. C. Raatgeep, I. L. Bonta, K. F. Kerrebijn, M. J. Mol, A. F. Stalenhoef, P. M. Stuyt, A. van 't Laar, A. A. M. Ermens, M. Schoester, J. Lindemans, J. Abels, M. A. van Baak, J. M. V. Mooij, P. M. H. Schiffers, J. F. M. Wetzels, J. D. v. Berqeyk, F. H. J. A. v. Heusden, F. Th. M. Huysmans, A. J. Hoitsma, R. A. P. Koene, H. M. L. Jansen, F. G. M. Russel, A. C. Wouterse, C. A. M. van Ginneken, Y. W. A. v. d. Pol, E. G. E. de Vries, J. Greidanus, N. H. Mulder, D. Th. Sleijfer, P. H. B. Willemse, D. R. A. Uges, P. A. B. M. Smits, J. W. Louwerenburg, J. H. Kingma, F. N. IJdenberg, F. G. J. Poelma, R. Breŝ, J. J. Tukker, H. P. Remmert, M. Olling, W. Slob, W. van der Giesen, A. G. Rauws, E. A. Runhaar, J. P. Neijt, J. J. M. Holthuis, D. de Vos, J J Tukker, F G J Poelma, H. H. W. Thijssen, K. Hamulyák, C. Franssen, H. Wollersheim, R. W. M. M. Jansen, H. J. J. van Lier, W. H. L. Hoefnagels, C. Grgen, M-A. Horan, Z. A. R. Oomerjee, D. D. Breimer, C. F. A. van Bezooijen, H. J. Keizer, F. J. Cleton, E. A. de Bruijn, U. R. Tiaden, A. de Boer, J. C. J. Stiekema, M. Danhof

Publikováno v: Pharmaceutisch Weekblad. 10:178-184

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b2b9f9514cb9f26f9956005c8dcb5f7f
https://doi.org/10.1007/bf01959428

The use of ciprofloxacin in the treatment of patients with cystic fibrosis

Autor: C. Van Gulpen, W. Bakker, P. J. van den Broek, H. Mattie

Publikováno v: Pharmaceutisch weekblad. Scientific edition.

The use of ciprofloxacin for the treatment of pulmonary infection in cystic fibrosis patients was investigated. Therapy was successful in six patients and unsuccessful in three patients. In one patient therapy had to be stopped because serum transami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f10370ead76b3fb27b75e66268386c1
https://pubmed.ncbi.nlm.nih.gov/3438152

Determination of benzylpenicillin and probenecid in human body fluids by high-performance liquid chromatography

Autor: M. van der Kaay, A.W. Brokerhof, U.R. Tjaden, Herman Mattie, C. Van Gulpen

Publikováno v: Journal of chromatography. 381(2)

A method for the determination of benzylpenicillin and probenecid concentrations in human body fluids using ion-pair reversed-phase chromatography with UV detection has been developed. For plasma samples two extraction techniques were investigated. P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f01f8ac89dc9d6b73ac7e983fef063a
https://pubmed.ncbi.nlm.nih.gov/3760092

The pharmacokinetics of metronidazole and tinidazole in patients with mixed aerobic--anaerobic infections

Autor: B. A. C. Dijkmans, C. van Gulpen, Herman Mattie

Publikováno v: The Journal of antimicrobial chemotherapy. 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ef5bb8840d8f1907e49ec537d392f1
https://pubmed.ncbi.nlm.nih.gov/7118776