Výsledky vyhledávání - "C. van Bruggen"

Akademický článek

Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells

Autor: Eric Eldering, Lisette Waanders, Lieve E H van der Donk, Louis S Ates, Janneke Maaskant, John L van Hamme, Jaco A C van Bruggen, Joanne M Rietveld, Wilbert Bitter, Teunis B H Geijtenbeek, Coenraad P Kuijl

Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 11, Iss 4 (2023)

Background Interferon (IFN)-β induction via activation of the stimulator of interferon genes (STING) pathway has shown promising results in tumor models. STING is activated by cyclic dinucleotides such as cyclic GMP–AMP dinucleotides with phosphod

Externí odkaz: https://doaj.org/article/31940c490bd64fc09c995d4d78516705

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Akademický článek

Healthy Ageing and Intellectual Disability study: summary of findings and the protocol for the 10-year follow-up study

Autor: Patrick J E Bindels, Roy G Elbers, Marleen J de Leeuw, Alyt Oppewal, Mireille W E J Knulst, Marco C van Maurik, Marjoleine C van Bruggen, Thessa I M Hilgenkamp, Dederieke A M Maes-Festen

Publikováno v: BMJ Open, Vol 12, Iss 2 (2022)

Externí odkaz: https://doaj.org/article/4d3d4d3d9e584230ba85222a3f28a168

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Akademický článek

Indirect Effects of the Herbicide Glyphosate on Plant, Animal and Human Health Through its Effects on Microbial Communities

Autor: A. H. C. van Bruggen, M. R. Finckh, M. He, C. J. Ritsema, P. Harkes, D. Knuth, V. Geissen

Publikováno v: Frontiers in Environmental Science, Vol 9 (2021)

The herbicide glyphosate interferes with the shikimate pathway in plants and in major groups of microorganisms impeding the production of aromatic amino acids. Glyphosate application on plants results in a slow death, accelerated by reduced resistanc

Externí odkaz: https://doaj.org/article/88a6e272515b404cb8d15c8f77bfff57

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Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment

Autor: Zhenghao Chen, Helga Simon-Molas, Gaspard Cretenet, Beatriz Valle-Argos, Lindsay D. Smith, Francesco Forconi, Bauke V. Schomakers, Michel van Weeghel, Dean J. Bryant, Jaco A. C. van Bruggen, Fleur S. Peters, Jeffrey C. Rathmell, Gerritje J. W. van der Windt, Arnon P. Kater, Graham Packham, Eric Eldering

Publikováno v: Blood, 140(6), 630-643. American Society of Hematology
Chen, Z, Simon-Molas, H, Cretenet, G, Valle-Argos, B, Smith, L D, Forconi, F, Schomakers, B V, van Weeghel, M, Bryant, D J, van Bruggen, J A C, Peters, F S, Rathmell, J C, van der Windt, G J W, Kater, A P, Packham, G & Eldering, E 2022, ' Characterization of metabolic alterations of chronic lymphocytic leukemia in the lymph node microenvironment ', Blood, vol. 140, no. 6, pp. 630-643 . https://doi.org/10.1182/blood.2021013990

Altered metabolism is a hallmark of both cell division and cancer. Chronic lymphocytic leukemia (CLL) cells circulate between peripheral blood (PB) and lymph nodes (LNs), where they receive proliferative and prosurvival signals from surrounding cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94178f7d4262014e777d0dddbec2e94e
http://www.scopus.com/inward/record.url?scp=85132192009&partnerID=8YFLogxK

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Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells

Autor: Lisette Waanders, Lieve E H van der Donk, Louis S Ates, Janneke Maaskant, John L van Hamme, Eric Eldering, Jaco A C van Bruggen, Joanne M Rietveld, Wilbert Bitter, Teunis B H Geijtenbeek, Coenraad P Kuijl

Publikováno v: Journal for immunotherapy of cancer, 11(4). BioMed Central Ltd.
Waanders, L, van der Donk, L E H, Ates, L S, Maaskant, J, van Hamme, J L, Eldering, E, van Bruggen, J A C, Rietveld, J M, Bitter, W, Geijtenbeek, T B H & Kuijl, C P 2023, ' Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells ', Journal for Immunotherapy of Cancer, vol. 11, no. 4, jitc-2022-005839, pp. 1-13 . https://doi.org/10.1136/jitc-2022-005839
Journal for Immunotherapy of Cancer, 11(4):jitc-2022-005839. BioMed Central
Waanders, L, van der Donk, L E H, Ates, L S, Maaskant, J, van Hamme, J L, Eldering, E, van Bruggen, J A C, Rietveld, J M, Bitter, W, Geijtenbeek, T B H & Kuijl, C P 2023, ' Ectopic expression of cGAS in Salmonella typhimurium enhances STING-mediated IFN-β response in human macrophages and dendritic cells ', Journal for Immunotherapy of Cancer, vol. 11, no. 4, jitc-2022-005839 . https://doi.org/10.1136/jitc-2022-005839
Journal for Immunotherapy of Cancer, 11(4):jitc-2022-005839, 1-13. BioMed Central

BackgroundInterferon (IFN)-β induction via activation of the stimulator of interferon genes (STING) pathway has shown promising results in tumor models. STING is activated by cyclic dinucleotides such as cyclic GMP–AMP dinucleotides with phosphodi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2149b7bf3d883993fac5482fcf45611a
https://pure.amc.nl/en/publications/ectopic-expression-of-cgas-in-salmonella-typhimurium-enhances-stingmediated-ifn-response-in-human-macrophages-and-dendritic-cells(946d907b-8e7c-4291-b92d-ff52383ad71b).html

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Depletion of CLL cells by venetoclax treatment reverses oxidative stress and impaired glycolysis in CD4 T cells

Autor: J. A. C. van Bruggen, G. J. W. van der Windt, M. Hoogendoorn, J. Dubois, Arnon P. Kater, F. S. Peters

Publikováno v: Blood advances, 6(14):14, 4185-4195. American Society of Hematology
Blood, 6(14), 4185-4195. American Society of Hematology
van Bruggen, J A C, van der Windt, G J W, Hoogendoorn, M, Dubois, J, Kater, A P & Peters, F S 2022, ' Depletion of CLL cells by venetoclax treatment reverses oxidative stress and impaired glycolysis in CD4 T cells ', Blood, vol. 6, no. 14, pp. 4185-4195 . https://doi.org/10.1182/bloodadvances.2022007034
Blood advances. American Society of Hematology

Acquired T-cell dysfunction is characteristic of chronic lymphocytic leukemia (CLL) and is associated with reduced efficacy of T cell–based therapies. A recently described feature of dysfunctional CLL-derived CD8 T cells is reduced metabolic plasti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::915cce59982bfb2da80f8394cb2cf11d
https://pure.amc.nl/en/publications/depletion-of-cll-cells-by-venetoclax-treatment-reverses-oxidative-stress-and-impaired-glycolysis-in-cd4-t-cells(00276d61-cea4-4d1c-92c1-c5034bbb7044).html

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Human CXCR5+PD-1+ CD8 T cells in healthy individuals and patients with hematologic malignancies

Autor: Mark-David Levin, Sanne H. Tonino, Sjoerd T.T. Schetters, Ester B. M. Remmerswaal, Adriaan D. Bins, Frederike J. Bemelman, Arnon P. Kater, Renate de Boer, Tom Hofland, Anne W. J. Martens, Eric Eldering, Jaco A. C. van Bruggen

Publikováno v: European Journal of Immunology
European journal of immunology, 51(3), 703-713. Wiley-VCH Verlag

Immune checkpoint blockade (ICB) has revolutionized cancer therapy, but varying response rates illustrate the need for biomarkers of response. Studies in mice have identified a subset of CD8 T cells that is essential for response to PD‐1 ICB. These

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e54714957e1ea10a7a855bd9a6c9aaa0
https://doi.org/10.1002/eji.202048761

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Akademický článek

Illuminating the Sites of Enterovirus Replication in Living Cells by Using a Split-GFP-Tagged Viral Protein

Autor: H. M. van der Schaar, C. E. Melia, J. A. C. van Bruggen, J. R. P. M. Strating, M. E. D. van Geenen, A. J. Koster, M. Bárcena, F. J. M. van Kuppeveld

Publikováno v: mSphere, Vol 1, Iss 4 (2016)

ABSTRACT Like all other positive-strand RNA viruses, enteroviruses generate new organelles (replication organelles [ROs]) with a unique protein and lipid composition on which they multiply their viral genome. Suitable tools for live-cell imaging of e

Externí odkaz: https://doaj.org/article/d1b2b96f81524978aa1d32d7516d2efd

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Host density dependence and environmental factors affecting laurel wilt disease incidence

Autor: H. L. Er, Gretchen E. Pruett, Robin A. Choudhury, James J. Marois, Jason A. Smith, Randy C. Ploetz, Karen A. Garrett, Joshua L. Konkol, Ariena H. C. van Bruggen, Marc A. Hughes

Publikováno v: Plant Pathology. 70:676-688

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5264945a4da31d81d429799100991c5e
https://doi.org/10.1111/ppa.13314

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Healthy Ageing and Intellectual Disability study

Autor: Marleen J de Leeuw, Alyt Oppewal, Roy G Elbers, Mireille W E J Knulst, Marco C van Maurik, Marjoleine C van Bruggen, Thessa I M Hilgenkamp, Patrick J E Bindels, Dederieke A M Maes-Festen

Publikováno v: BMJ Open, 12(2):e053499. BMJ Publishing Group

IntroductionThe Healthy Ageing and Intellectual Disability (HA-ID) study is a prospective multicentre cohort study in the Netherlands that started in 2008, including 1050 older adults (aged ≥50) with intellectual disabilities (ID). The study is des

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7d35ee3e6c9d3188a28a15e9ff5756d
https://doi.org/10.1136/bmjopen-2021-053499

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