Zobrazeno 1 - 10
of 141
pro vyhledávání: '"C. van Bree"'
Publikováno v:
British journal of cancer, 98(7), 1226-1233. Nature Publishing Group
British Journal of Cancer
British Journal of Cancer
The deoxycytidine analogue 2',2'-difluoro-2'-deoxycytidine (dFdC, gemcitabine) is a potent radiosensitiser, but has limited efficacy in combination with radiotherapy in patients with pancreatic cancer due to acute toxicity. We investigated whether cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::961e10c3489a813c84a9b9ebcc82da2f
https://doi.org/10.1038/sj.bjc.6604287
https://doi.org/10.1038/sj.bjc.6604287
Autor:
Nicolaas A. P. Franken, Jaap Haveman, G.J. Peters, C. van Bree, N. Castro Kreder, J. Sigmond, Willem J.P Loves
Publikováno v:
Nucleosides, nucleotides & nucleic acids, 25(9-11), 1177-1180. Marcel Dekker Inc.
In both pulsed low dose rate (LDR) and single high dose radiation schedules, gemcitabine pretreatment sensitizes tumor cells to radiation. These radiosensitizing effects could be the result of decreased DNA repair. In this study, the effect of irradi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10080f68b6357e9be161497a984b8ae
https://doi.org/10.1080/15257770600894394
https://doi.org/10.1080/15257770600894394
Publikováno v:
Mutation research, 594(1-2), 148-154. Elsevier
Purpose Cisplatin was found to radiosensitize SW-1573 cells by inhibition of PLDR. Therefore, it was investigated whether cisplatin combined with γ-radiation leads to an increase in the number of chromosomal aberrations or apoptotic cells compared w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b3125476e217da6ee3d2ed36425913
https://doi.org/10.1016/j.mrfmmm.2005.08.002
https://doi.org/10.1016/j.mrfmmm.2005.08.002
Publikováno v:
Radiation research, 161(5), 511-516. Radiation Research Society
van Bree, C., Franken, N. A. P., Rodermond, H. M., Stalpers, L. J. A. and Haveman, J. Repair of Potentially Lethal Damage does not Depend on Functional TP53 in Human Glioblastoma Cells. Radiat. Res. 161, 511–516 (2004). The functionality of G1-phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449d03c1cc4b8a2db49e6b246c54e850
https://doi.org/10.1667/3154
https://doi.org/10.1667/3154
Publikováno v:
Radiation research, 161(5), 504-510. Radiation Research Society
The inactivation of TP53 by transfection of a dominant-negative mutated TP53 (MP53.13 cells) was compared with inactivation of TP53 by transfection with the HPV E6 gene (RC10.1 cells) with respect to PLD repair, G(1)-phase arrest, and induction of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6230688ebb05fc111dabe955474c5a1a
https://doi.org/10.1667/rr3160
https://doi.org/10.1667/rr3160
Publikováno v:
International journal of radiation biology, 78(3), 203-210. Informa Healthcare
Purpose: To determine whether measurement of chromosome aberrations by fluorescence in situ hybridization (FISH) predicts cell survival after irradiation at different dose-rates and after radiosensitization by bromodeoxyurdine (BrdU) in a lung carcin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cc66a0cd606fd20f1e6162c1bd5cd62
https://doi.org/10.1080/09553000110104074
https://doi.org/10.1080/09553000110104074
Publikováno v:
International journal of hyperthermia, 17(4), 337-346. Informa Healthcare
The objective was to test the hypothesis that wild-type p53-function is required for the enhancement of the cytotoxicity of cis-diammine-dichloroplatinum(II) (cDDP) cytotoxicity by hyperthermia (HT). Human colorectal carcinoma cells (RKO) with wild-t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e5ed23c3e9c85f2a8705e0110772a1
https://doi.org/10.1080/02656730110053137
https://doi.org/10.1080/02656730110053137
Publikováno v:
International Journal of Hyperthermia. 17:337-346
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe766898a78b28ad4b4d5e883a9aba81
https://doi.org/10.1080/02656730117221
https://doi.org/10.1080/02656730117221
Autor:
Jaap Haveman, B. Van Der Maat, Nicolaas A. P. Franken, Piet J. M. Bakker, C. van Bree, H. M. Ceha
Publikováno v:
Journal of cancer research and clinical oncology, 125(10), 549-555. Springer Verlag
Cell-cycle checkpoints are thought to govern the cellular response to external stimuli. The involvement of the p53 tumour-suppressor protein and the retinoblastoma protein (pRb) in the cell-cycle checkpoint in G1 phase is well established. However, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b015b09675ffb38e6364856759e97be0
https://doi.org/10.1007/s004320050315
https://doi.org/10.1007/s004320050315
Publikováno v:
International Journal of Hyperthermia. 11:561-573
Investigations were performed to assess the influence of hyperthermia on the pharmacokinetics of a chemotherapeutic drug and on the effectiveness of combined treatments for induction of tumour cell death and growth delay of experimental tumours. Trea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05486e4276dc1ebe9befd390db40a4b
https://doi.org/10.3109/02656739509022490
https://doi.org/10.3109/02656739509022490