Zobrazeno 1 - 10
of 2 238
pro vyhledávání: '"C. Yuen"'
Autor:
Shengjie Ying, Tracy Heung, Bhooma Thiruvahindrapuram, Worrawat Engchuan, Yue Yin, Christina Blagojevic, Zhaolei Zhang, Robert A. Hegele, Ryan K. C. Yuen, Anne S. Bassett
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-11 (2023)
Abstract Background Elevated triglyceride (TG) levels are a heritable and modifiable risk factor for cardiovascular disease and have well-established associations with common genetic variation captured in a polygenic risk score (PRS). In young adulth
Externí odkaz:
https://doaj.org/article/e3b86bf5315244c5ade858fc4967c998
Autor:
Adrienne Y. L. Chan, Andrew S. C. Yuen, Daniel H. T. Tsai, Wallis C. Y. Lau, Yogini H. Jani, Yingfen Hsia, David P. J. Osborn, Joseph F. Hayes, Frank M. C. Besag, Edward C. C. Lai, Li Wei, Katja Taxis, Ian C. K. Wong, Kenneth K. C. Man
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Recent studies raised concerns about the increasing use of gabapentinoids in different countries. With their potential for misuse and addiction, understanding the global consumption of gabapentinoids will offer us a platform to examine the n
Externí odkaz:
https://doaj.org/article/7c6afee1350947d0b78c7bfd6ea10a65
Autor:
Shengjie Ying, Tracy Heung, Bhooma Thiruvahindrapuram, Worrawat Engchuan, Yue Yin, Christina Blagojevic, Zhaolei Zhang, Robert A. Hegele, Ryan K. C. Yuen, Anne S. Bassett
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/54f72e4c11a44f9ea01fd0644ba18273
Publikováno v:
Biology Open, Vol 11, Iss 5 (2022)
Extracellular signal-regulated kinase (ERK) lies downstream of a core signalling cascade that controls all aspects of development and adult homeostasis. Recent developments have led to new tools to image and manipulate the pathway. However, visualisi
Externí odkaz:
https://doaj.org/article/b01851db000e420883205a8fc9dba3ca
Autor:
Bahareh A. Mojarad, Yue Yin, Roozbeh Manshaei, Ian Backstrom, Gregory Costain, Tracy Heung, Daniele Merico, Christian R. Marshall, Anne S. Bassett, Ryan K. C. Yuen
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The range of genetic variation with potential clinical implications in schizophrenia, beyond rare copy number variants (CNVs), remains uncertain. We therefore analyzed genome sequencing data for 259 unrelated adults with schizophrenia from a
Externí odkaz:
https://doaj.org/article/4ade2880bac94536bb258a0181cb9e63
Rare and low frequency genomic variants impacting neuronal functions modify the Dup7q11.23 phenotype
Autor:
Farah Qaiser, Yue Yin, Carolyn B. Mervis, Colleen A. Morris, Bonita P. Klein-Tasman, Elaine Tam, Lucy R. Osborne, Ryan K. C. Yuen
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 16, Iss 1, Pp 1-11 (2021)
Abstract Background 7q11.23 duplication (Dup7) is one of the most frequent recurrent copy number variants (CNVs) in individuals with autism spectrum disorder (ASD), but based on gold-standard assessments, only 19% of Dup7 carriers have ASD, suggestin
Externí odkaz:
https://doaj.org/article/850b47c9a2c641a4801f7fc30fe86317
Autor:
Giulia F. Del Gobbo, Yue Yin, Sanaa Choufani, Emma A. Butcher, John Wei, Evica Rajcan-Separovic, Hayley Bos, Peter von Dadelszen, Rosanna Weksberg, Wendy P. Robinson, Ryan K. C. Yuen
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-12 (2021)
Abstract Background Fetal growth restriction (FGR) is associated with increased risks for complications before, during, and after birth, in addition to risk of disease through to adulthood. Although placental insufficiency, failure to supply the fetu
Externí odkaz:
https://doaj.org/article/88b82984e8b44269838acbf69c082f6d
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
The 22q11.2 deletion is associated with >20-fold increased risk for schizophrenia. The presence of gene DGCR8 in the 22q11.2 deletion region has suggested microRNA (miRNA) dysregulation as possibly contributing to this risk. We therefore investigated
Externí odkaz:
https://doaj.org/article/fe29874ba44847369e3e704a68df4b3e
Autor:
Santiago R. Gonzalez, James C. Yuen
Publikováno v:
JPRAS Open, Vol 25, Iss , Pp 24-29 (2020)
The literature describes numerous successful applications using dermal regeneration templates such as IntegraⓇ. Despite widespread use for burns, trauma, and chronic wounds among others, Integra has associated complications which need continued inv
Externí odkaz:
https://doaj.org/article/810e3416799b473fa69b211e0cfae09f
Autor:
L. D’Abate, S. Walker, R. K. C. Yuen, K. Tammimies, J. A. Buchanan, R. W. Davies, B. Thiruvahindrapuram, J. Wei, J. Brian, S. E. Bryson, K. Dobkins, J. Howe, R. Landa, J. Leef, D. Messinger, S. Ozonoff, I. M. Smith, W. L. Stone, Z. E. Warren, G. Young, L. Zwaigenbaum, S. W. Scherer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Siblings of those with autism spectrum disorder (ASD) have increased likelihood of ASD or related subclinical traits. Here, studying 253 ASD families, D’Abate et al. test the predictive value of genomic copy number variation involving ASD-associate
Externí odkaz:
https://doaj.org/article/7940f1b2c2924eec84eda8740660d6c8