Zobrazeno 1 - 10
of 80
pro vyhledávání: '"C. Xidakis"'
Autor:
Elias A. Kouroumalis, Stefanos Klironomos, George Notas, Foteini Kiagiadaki, C. Xidakis, Ourania Sfakianaki
Publikováno v:
Regulatory Peptides. 188:5-12
Background and aims Somatostatin and its analogs may influence hepatic fibrosis interfering through several mechanisms. The aim of this study was to investigate the effect of octreotide on cytokine activated hepatic stellate cells (HSC). Methods Prim
Publikováno v:
Journal of Viral Hepatitis. 8:63-69
Autor:
Pinelopi Manousou, C. Xidakis, George Notas, George Kolios, Vassilis Valatas, Elias A. Kouroumalis
Publikováno v:
Molecular and Cellular Biochemistry. 319:91-98
Nitric oxide (NO) and Monocyte Chemoattractant Protein (MCP)-1 co-regulation has been found in endotoxin-activated macrophages. Kupffer cells (KC) are a main source of soluble-mediators production in liver abnormalities. We investigated in vitro simi
Autor:
Elias A. Kouroumalis, George Notas, C. Xidakis, E. Renieri, Niki Mastrodimou, George Kolios, Kyriaki Thermos
Publikováno v:
Regulatory Peptides. 143:76-82
The present study investigated the presence of somatostatin receptor subtypes (ssts) and the endogenous peptides somatostatin and cortistatin in rat Kupffer cells, since modulation of these cells by somatostatin may be important for the beneficial ef
Autor:
Konstantinos Karmiris, C. Xidakis, Elias A. Kouroumalis, Ioannis E. Koutroubakis, Maria Polychronaki
Publikováno v:
European Journal of Gastroenterology & Hepatology. 19:789-794
Tumour necrosis factor alpha is a critical mediator of inflammation-related altered metabolism in inflammatory bowel disease (IBD), possibly through its interaction with adipokines, which play an important role in IBD. Infliximab is a well establishe
Autor:
Elias A. Kouroumalis, Dushanka Ljumovic, C. Xidakis, Pinelopi Manousou, Vassilis Valatas, George Notas, George Kolios
Publikováno v:
Digestive Diseases and Sciences. 50:935-941
Kupffer cells may be involved in liver fibrogenesis through production of TGF-beta1. Their role in fibrinolysis is less clear. Octreotide, a synthetic analogue of somatostatin, is often used in cirrhotic patients. Its effect on Kupffer cells was stud
Autor:
George Kolios, C. Xidakis, Pinelopi Manousou, Elias A. Kouroumalis, George Notas, Vassilis Valatas, Dusanka Ljumovic
Publikováno v:
Regulatory Peptides. 120:215-225
Aims: We studied the production of inflammatory mediators by rat KC and the possible in vitro effect of the somatostatin analogue octreotide. Methods: Primary KC cultures were incubated with LPS added alone or with different concentrations of octreot
Autor:
George Kolios, Elias A. Kouroumalis, C. Xidakis, Vassilis Valatas, George Notas, Pinelopi Manousou, Ioannis Diamantis
Publikováno v:
British Journal of Pharmacology. 141:477-487
Kupffer cells (KC) and lipopolysaccharide (LPS) interaction is the initial event leading to hepatic inflammation and fibrosis in many types of liver injury. We studied chemokine secretion by KC activated with LPS and the possible effect of the somato
Publikováno v:
Cell Biology International. 27:67-73
We report a four-step procedure that optimizes the methodology for isolation of highly purified rat Kupffer cells (KC). We combined the previously reported techniques of enzymatic tissue treatment, density gradient centrifugation, centrifugal elutria
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