Zobrazeno 1 - 10
of 62
pro vyhledávání: '"C. Wynants"'
Autor:
J.‐P. Bouillon, J. Feneau-Dupont, C. Wynants, Bernard Tinant, Jean-Paul Declercq, Zdenek Janousek, Hg. Viehe
Publikováno v:
Bulletin des Sociétés Chimiques Belges. 103:243-255
Heterocyclizations of 1,4-bis-nucleophiles with the new 3-trifluoroacetyl-lactams 1a-c differ from 1,2- or 1,3-bisnucleophiles since they proceed without opening of the lactam structure to give benzoxazolidines 4-6, benzothiazolidines 7-9 and benzimi
Publikováno v:
International Journal of Peptide and Protein Research. 25:615-621
The possible conformations of SMS 201-995, an active analogue of somastostatin, have been studied in dimethylsulfoxide solution by 500 MHz proton n.m.r. spectroscopy. The assignments have been made by use of 2D-correlated methods to detect long-range
Publikováno v:
International Journal of Peptide and Protein Research. 25:608-614
The conformations of a cyclic analogue of somatostatin, SMS 201-995, have been studied by n.m.r. spectroscopy at 500 MHz in aqueous solution. Assignments were made by use of 2D-correlated methods, especially by detecting long-range connectivities in
Publikováno v:
International Journal of Peptide and Protein Research. 30:541-547
The cyclic analogue of somatostatin (SRIF), D-Phe-Cys-Tyr-D-Trp-Lys-Thr-Cys-Thr-NH2 (CTC), exhibits good affinity for both opioid and SRIF receptor systems. Its conformational properties were examined in water by high-field proton n.m.r. spectroscopy
Publikováno v:
International Journal of Peptide and Protein Research. 25:622-627
The conformational properties of the somatostatin analogue 201-456 (1) have been studied by high field n.m.r. in DMSO. This analogue is the base structure of nine derivates synthesized by Bauer et al. and shows a very low biological activity, althoug
Publikováno v:
International Journal of Peptide and Protein Research. 26:561-567
A somatostatin octapeptide analogue has been synthesized and its conformational properties have been studied by high field n.m.r. in water. All the proton signals of the individual amino acids have been assigned except for the aromatic protons, by us
Publikováno v:
International Journal of Peptide and Protein Research. 29:331-346
Two cyclic somatostatin analogues containing the active sequence Phe7-D-Trp8-Lys9-Thr10 and a meta- or para-(aminomethyl) phenylacetic acid (AMPA) spacer unit, have been synthesized. A conformational study using 2D n.m.r. techniques (COSY, NOESY) rev
Publikováno v:
International Journal of Peptide and Protein Research. 29:90-98
A series of nine closely related somatostatin analogues, containing the hexapeptide H-Cys2 -Phe3 -D-Trp4-Lys5 -Thr6 -Cys7-NH2 sequence have been synthesized by Bauer et al. The conformational properties of two of them, showing intermediate activities
Autor:
C. Wynants
As the telecommunication industry introduces new sophisticated technologies, the nature of services and the volume of demands have changed. Indeed, a broad range of new services for users appear, combining voice, data, graphics, video, etc. This impl
Publikováno v:
Journal f�r Praktische Chemie/Chemiker-Zeitung. 338:538-543
3-Trifluoroacetyl- and other 3-acyl-1-methyl-lactams (1-5) undergo the Robinson annelation with alpha,beta-unsaturated ketones to produce spirocyclic cyclohexenones (6), their precursors hydroxycyclohexanones (7) or 3-acyl-3-oxobutyl-lactams (8) depe