Zobrazeno 1 - 10 of 213 pro vyhledávání: '"C. Wychowski"'
1
Identification of GBF1 as a cellular factor required for hepatitis E virus RNA replication
Autor: Laurence Cocquerel, Catherine L. Jackson, Jérôme Gouttenoire, Yves Rouillé, Maliki Ankavay, Rayan Farhat, Nadjet Lebsir, Jean Dubuisson, Darius Moradpour, C. Wychowski
Publikováno v: Cellular Microbiology
The hepatitis E virus (HEV) genome is a single‐stranded, positive‐sense RNA that encodes three proteins including the ORF1 replicase. Mechanisms of HEV replication in host cells are unclear, and only a few cellular factors involved in this step h
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90ea8415082fe1cb7fb3bf7b2c54edb
https://pubmed.ncbi.nlm.nih.gov/29112323
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3
New insights into the understanding of hepatitis C virus entry and cell-to-cell transmission by using the ionophore Monensin A
Autor: Sandrine Belouzard, Dimitri Lavillette, Didier Hober, Laurence Cocquerel, Yves Rouillé, Florian Douam, Noémie Calland, Thibaut Vausselin, Famara Sane, C. Wychowski, Thomas F. Baumert, Julie Potel, Jean Dubuisson, Véronique Descamps, Lucie Fénéant, Gilles Duverlie, Catherine François
Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2015, 89 (16), pp.8346-64. ⟨10.1128/JVI.00192-15⟩
Journal of Virology, 2015, 89 (16), pp.8346-64. ⟨10.1128/JVI.00192-15⟩
In our study, we characterized the effect of monensin, an ionophore that is known to raise the intracellular pH, on the hepatitis C virus (HCV) life cycle. We showed that monensin inhibits HCV entry in a pangenotypic and dose-dependent manner. Monens
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4909adac1a55bae9e7e9ce2e1823a70
https://hal-univ-lyon1.archives-ouvertes.fr/hal-02487305
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4
Expression and identification of hepatitis C virus polyprotein cleavage products
Autor: C. Wychowski, Charles M. Rice, Arash Grakoui, Stephen M. Feinstone, Chih-Ping Lin
Publikováno v: Journal of Virology. 67:1385-1395
Hepatitis C virus (HCV) is the major cause of transfusion-acquired non-A, non-B hepatitis. HCV is an enveloped positive-sense RNA virus which has been classified as a new genus in the flavivirus family. Like the other two genera in this family, the f
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3daad4151caa199b2ec0a9d6e1b11fe6
https://doi.org/10.1128/jvi.67.3.1385-1395.1993
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6
An epitope in hepatitis C virus core region recognized by cytotoxic T cells in mice and humans
Autor: T Akatsuka, C Wychowski, S M Feinstone, J A Berzofsky, C D Pendleton, Mutsunori Shirai, R Houghten, Mikio Nishioka, H Okada
Publikováno v: Journal of virology. 68(5)
Several cytotoxic T-lymphocyte (CTL) epitopes have been defined in hepatitis C virus (HCV) proteins. CTL may play an important role in the control of infection by HCV. Here, we identify a highly conserved antigenic site in the HCV core recognized by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fe0192c76c113dd1c2ebf742db7aeb
https://pubmed.ncbi.nlm.nih.gov/7512163
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8
Induction of cytotoxic T cells to a cross-reactive epitope in the hepatitis C virus nonstructural RNA polymerase-like protein
Autor: Toshitaka Akatsuka, Mutsunori Shirai, R Houghten, C D Pendleton, S M Feinstone, C Wychowski, Jay A. Berzofsky, K Mihalik
Publikováno v: Journal of virology. 66(7)
Cytotoxic T lymphocytes (CTL) have been found to mediate protection in vivo against certain virus infections. CTL also may play an important role in control of infection by hepatitis C virus (HCV), but no CTL epitopes have yet been defined in any HCV
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fd0d799712219a772b3e880db7639d6
https://pubmed.ncbi.nlm.nih.gov/1376366
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9
Interaction of immune sera with synthetic peptides corresponding to the structural protein region of hepatitis C virus
Autor: Harvey J. Alter, C L Davies, H Wang, W M Ching, M Carl, M J Beach, Daniel W. Bradley, Stephen M. Feinstone, C Wychowski, James Wai-Kuo Shih
Comparison of the deduced amino acid sequence from the structural region of the Hutchinson strain of hepatitis C virus (HCV-H) with four other HCV isolates clearly divides the five isolates into two groups based on sequence homology. The first group
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1abbd5765b9706dbab4e6165f242810
https://europepmc.org/articles/PMC48831/
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10
Three-dimensional structure of a mouse-adapted type 2/type 1 poliovirus chimera
Autor: David Jacobson, C. Wychowski, David J. Filman, A. Martin, James M. Hogle, M. Girard, Todd O. Yeates
Publikováno v: Europe PubMed Central
The crystal structure of V510, a chimeric type 2/type 1 poliovirus, has been determined at 2.6 A resolution. Unlike the parental Mahoney strain of type 1 poliovirus, V510 is able to replicate in the mouse central nervous system, due entirely to the r
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d26535e9862d5740bee8f1bfc1128e2
https://pubmed.ncbi.nlm.nih.gov/1651227
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