Zobrazeno 1 - 10
of 458
pro vyhledávání: '"C. Wilkes"'
Publikováno v:
Frontiers in Rehabilitation Sciences, Vol 4 (2023)
IntroductionShared decision making is a concept in healthcare that actively involves patients in the management of their condition. The process of shared decision making is taught in clinical training programmes, including Audiology, where there are
Externí odkaz:
https://doaj.org/article/543ee58d526e4605b0732bb14fc71470
Autor:
Kyrillus S. Shohdy, Rohan Bareja, Michael Sigouros, David C. Wilkes, Princesca Dorsaint, Jyothi Manohar, Daniel Bockelman, Jenny Z. Xiang, Rob Kim, Kentaro Ohara, Kenneth Eng, Juan Miguel Mosquera, Olivier Elemento, Andrea Sboner, Alicia Alonso, Bishoy M. Faltas
Publikováno v:
npj Genomic Medicine, Vol 6, Iss 1, Pp 1-10 (2021)
Abstract The availability of fresh frozen (FF) tissue is a barrier for implementing RNA sequencing (RNA-seq) in the clinic. The majority of clinical samples are stored as formalin-fixed, paraffin-embedded (FFPE) tissues. Exome capture platforms have
Externí odkaz:
https://doaj.org/article/be290d96afc142fb9fcbd3a2e94604c7
Autor:
Mayumi Sugita, David C. Wilkes, Rohan Bareja, Kenneth W. Eng, Sarah Nataraj, Reyna A. Jimenez-Flores, LunBiao Yan, Jeanne Pauline De Leon, Jaclyn A. Croyle, Justin Kaner, Swathi Merugu, Sahil Sharma, Theresa Y. MacDonald, Zohal Noorzad, Palak Panchal, Danielle Pancirer, Shuhua Cheng, Jenny Z. Xiang, Luke Olson, Koen Van Besien, David S. Rickman, Susan Mathew, Wayne Tam, Mark A. Rubin, Himisha Beltran, Andrea Sboner, Duane C. Hassane, Gabriela Chiosis, Olivier Elemento, Gail J. Roboz, Juan Miguel Mosquera, Monica L. Guzman
Publikováno v:
npj Precision Oncology, Vol 5, Iss 1, Pp 1-10 (2021)
Abstract The epichaperome is a new cancer target composed of hyperconnected networks of chaperome members that facilitate cell survival. Cancers with an altered chaperone configuration may be susceptible to epichaperome inhibitors. We developed a flo
Externí odkaz:
https://doaj.org/article/9b26f08bf6d444edb5f3140c7fcddf4c
Autor:
Aram Vosoughi, Tuo Zhang, Kyrillus S. Shohdy, Panagiotis J. Vlachostergios, David C. Wilkes, Bhavneet Bhinder, Scott T. Tagawa, David M. Nanus, Ana M. Molina, Himisha Beltran, Cora N. Sternberg, Samaneh Motanagh, Brian D. Robinson, Jenny Xiang, Xiao Fan, Wendy K. Chung, Mark A. Rubin, Olivier Elemento, Andrea Sboner, Juan Miguel Mosquera, Bishoy M. Faltas
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
The role of germline variation in human cancers is not fully understood. Here, the authors define the landscape of putative deleterious germline variants that abrogate tumor suppressor proteins in advanced urothelial cancer patients.
Externí odkaz:
https://doaj.org/article/841aaee60ec54eb68cb48ba20fbccfd4
Autor:
M. C. Wilkes, K. Siva, J. Chen, G. Varetti, M. Y. Youn, H. Chae, F. Ek, R. Olsson, T. Lundbäck, D. P. Dever, T. Nishimura, A. Narla, B. Glader, H. Nakauchi, M. H. Porteus, C. E. Repellin, H. T. Gazda, S. Lin, M. Serrano, J. Flygare, K. M. Sakamoto
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Diamond Blackfan Anemia (DBA) is a congenital bone marrow failure syndrome that is associated with anemia. Here, the authors examine the role of Nemo-like kinase (NLK) in erythroid cells in the pathogenesis of DBA and as a potential target for therap
Externí odkaz:
https://doaj.org/article/36f32df2c5f64f50a787e28db8a527f5
Autor:
T. D. Pering, E. J. Liu, K. Wood, T. C. Wilkes, A. Aiuppa, G. Tamburello, M. Bitetto, T. Richardson, A. J. S. McGonigle
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Combining multiple ultraviolet cameras with synchronous aerial measurements, the authors here present vent-specific gas compositions and fluxes for Stromboli volcano. The results show that gas compositions vary between different vents, mirroring diff
Externí odkaz:
https://doaj.org/article/cec565e292eb4900970ef009ea3a460a
Autor:
David J. Pisapia, Kentaro Ohara, Rohan Bareja, David C. Wilkes, Erika Hissong, Jaclyn A. Croyle, Joon-Hyung Kim, Jad Saab, Theresa Y. MacDonald, Shaham Beg, Catherine O’Reilly, Sarah Kudman, Mark A. Rubin, Olivier Elemento, Andrea Sboner, Jeffrey Greenfield, Juan Miguel Mosquera
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-11 (2020)
Abstract BCOR has been recognized as a recurrently altered gene in a subset of pediatric tumors of the central nervous system (CNS). Here, we describe a novel BCOR-CREBBP fusion event in a case of pediatric infiltrating astrocytoma and further probe
Externí odkaz:
https://doaj.org/article/27779ed425e6468893b7eaba6b3381ab
Autor:
Tehnuka Ilanko, Thomas D Pering, Thomas C Wilkes, Fredy Erlington Apaza Choquehuayta, Christoph Kern, Alejandro Diaz Moreno, Silvio De Angelis, Susana Layana, Felipe Rojas, Felipe Aguilera, Freddy Vasconez, Andrew J.S. McGonigle
Publikováno v:
Volcanica, Vol 2, Iss 2, Pp 239-252 (2019)
We used low-cost Raspberry Pi ultraviolet (UV) cameras to measure sulphur dioxide (SO2) fluxes from Sabancaya volcano, Peru, during eruptive activity on 27 April 2018. Light dilution corrections were made by operating instruments at two distances sim
Externí odkaz:
https://doaj.org/article/db39d03e91b5455f8d4ab0fc811934b9
Autor:
Shaham Beg, Rohan Bareja, Kentaro Ohara, Kenneth Wha Eng, David C. Wilkes, David J. Pisapia, Wael Al Zoughbi, Sarah Kudman, Wei Zhang, Rema Rao, Jyothi Manohar, Troy Kane, Michael Sigouros, Jenny Zhaoying Xiang, Francesca Khani, Brian D. Robinson, Bishoy M. Faltas, Cora N. Sternberg, Andrea Sboner, Himisha Beltran, Olivier Elemento, Juan Miguel Mosquera
Publikováno v:
Translational Oncology, Vol 14, Iss 1, Pp 100944- (2021)
Background: Frequency of clinically relevant mutations in solid tumors by targeted and whole-exome sequencing is ∼30%. Transcriptome analysis complements detection of actionable gene fusions in advanced cancer patients. Goal of this study was to de
Externí odkaz:
https://doaj.org/article/8726c544cc9845559727803f01fd27f6
Publikováno v:
Haematologica. 108:1222-1231
Diamond-Blackfan anemia (DBA) is a ribosomopathy that is characterized by macrocytic anemia, congenital malformations, and early onset during childhood. Genetic studies have demonstrated that most patients carry mutations in one of the 20 related gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::729196e610b6a00216b737b66a15c062
https://doi.org/10.3324/haematol.2022.282042
https://doi.org/10.3324/haematol.2022.282042