Zobrazeno 1 - 10
of 135
pro vyhledávání: '"C. Wiesmeijer"'
Autor:
Chris Happé, Kondababu Kurakula, Xiao-Qing Sun, Denielli da Silva Goncalves Bos, Nina Rol, Christophe Guignabert, Ly Tu, Ingrid Schalij, Karien C. Wiesmeijer, Olga Tura-Ceide, Anton Vonk Noordegraaf, Frances S. de Man, Harm Jan Bogaard, Marie-José Goumans
Publikováno v:
Cells, Vol 9, Iss 6, p 1422 (2020)
Background: Mutations in bone morphogenetic protein receptor type II (BMPR2) are leading to the development of hereditary pulmonary arterial hypertension (PAH). In non-hereditary forms of PAH, perturbations in the transforming growth factor-β (TGF-
Externí odkaz:
https://doaj.org/article/0258be1fdecb410e89fae97cee3ce1ca
Autor:
Calinda K E Dingenouts, Wineke Bakker, Kirsten Lodder, Karien C Wiesmeijer, Asja T Moerkamp, Janita A Maring, Helen M Arthur, Anke M Smits, Marie-José Goumans
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189805 (2017)
AimsHereditary Hemorrhagic Telangiectasia type-1 (HHT1) is a genetic vascular disorder caused by haploinsufficiency of the TGFβ co-receptor endoglin. Dysfunctional homing of HHT1 mononuclear cells (MNCs) towards the infarcted myocardium hampers card
Externí odkaz:
https://doaj.org/article/5e61c32fbfbc40819382bae5a8ae2141
Autor:
Anke M. Smits, Alwin de Jong, Margreet R. de Vries, Marie-José Goumans, Kondababu Kurakula, Kirsten Lodder, Paul H.A. Quax, Hans-Jurgen J. Mager, Karien C. Wiesmeijer, Calinda K. E. Dingenouts, Wineke Bakker
Publikováno v:
International Journal of Molecular Sciences, 22(4):2010, 1-19. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, 22(4). MDPI
Bakker, W, Dingenouts, C K E, Lodder, K, Wiesmeijer, K C, de Jong, A, Kurakula, K, Mager, H J J, Smits, A M, de Vries, M R, Quax, P H A & Goumans, M J T H 2021, ' Bmp receptor inhibition enhances tissue repair in endoglin heterozygous mice ', International Journal of Molecular Sciences, vol. 22, no. 4, 2010, pp. 1-19 . https://doi.org/10.3390/ijms22042010
International Journal of Molecular Sciences, Vol 22, Iss 2010, p 2010 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 4
International Journal of Molecular Sciences, 22(4). MDPI
Bakker, W, Dingenouts, C K E, Lodder, K, Wiesmeijer, K C, de Jong, A, Kurakula, K, Mager, H J J, Smits, A M, de Vries, M R, Quax, P H A & Goumans, M J T H 2021, ' Bmp receptor inhibition enhances tissue repair in endoglin heterozygous mice ', International Journal of Molecular Sciences, vol. 22, no. 4, 2010, pp. 1-19 . https://doi.org/10.3390/ijms22042010
International Journal of Molecular Sciences, Vol 22, Iss 2010, p 2010 (2021)
Hereditary hemorrhagic telangiectasia type 1 (HHT1) is a severe vascular disorder caused by mutations in the TGFβ/BMP co-receptor endoglin. Endoglin haploinsufficiency results in vascular malformations and impaired neoangiogenesis. Furthermore, HHT1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6553fd9c02efe074d4d70e8093091f4
https://hdl.handle.net/1887/3214289
https://hdl.handle.net/1887/3214289
Autor:
Denielli da Silva Goncalves Bos, Harm Jan Bogaard, Karien C. Wiesmeijer, Chris Happé, Nina Rol, Kondababu Kurakula, Ingrid Schalij, Ly Tu, Anton Vonk Noordegraaf, Marie-José Goumans, Frances S. de Man, Olga Tura-Ceide, Xiao Qing Sun, Christophe Guignabert
Publikováno v:
Cells
Volume 9
Issue 6
Happé, C, Kurakula, K, Sun, X Q, da Silva Goncalves Bos, D, Rol, N, Guignabert, C, Tu, L, Schalij, I, Wiesmeijer, K C, Tura-Ceide, O, Vonk Noordegraaf, A, de Man, F S, Bogaard, H J & Goumans, M J 2020, ' The BMP Receptor 2 in Pulmonary Arterial Hypertension : When and Where the Animal Model Matches the Patient ', Cells, vol. 9, no. 6 . https://doi.org/10.3390/cells9061422
Cells, Vol 9, Iss 1422, p 1422 (2020)
Cells, 9(6). MDPI Multidisciplinary Digital Publishing Institute
Cells, 9(6). MDPI
Volume 9
Issue 6
Happé, C, Kurakula, K, Sun, X Q, da Silva Goncalves Bos, D, Rol, N, Guignabert, C, Tu, L, Schalij, I, Wiesmeijer, K C, Tura-Ceide, O, Vonk Noordegraaf, A, de Man, F S, Bogaard, H J & Goumans, M J 2020, ' The BMP Receptor 2 in Pulmonary Arterial Hypertension : When and Where the Animal Model Matches the Patient ', Cells, vol. 9, no. 6 . https://doi.org/10.3390/cells9061422
Cells, Vol 9, Iss 1422, p 1422 (2020)
Cells, 9(6). MDPI Multidisciplinary Digital Publishing Institute
Cells, 9(6). MDPI
Background: Mutations in bone morphogenetic protein receptor type II (BMPR2) are leading to the development of hereditary pulmonary arterial hypertension (PAH). In non-hereditary forms of PAH, perturbations in the transforming growth factor-&beta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8ba0bf645066a015e6a4fe4b1bd6f04
https://hdl.handle.net/1887/3182733
https://hdl.handle.net/1887/3182733
Autor:
Robert Szulcek, Harm-Jan Bogaard, Iris van Zuijen, Christopher Huang, Catharina C. Wiesmeijer, Xiaoke Pan, Amer A. Rana, Maria Catalina Gomez-Puerto, Maarten van Dinther, Nicholas W. Morrell, Kondababu Kurakula, Marie-José Goumans, Peter ten Dijke
Publikováno v:
Journal of Pathology, 249(3), 356-367
Gomez-Puerto, M C, van Zuijen, I, Huang, C J Z, Szulcek, R, Pan, X, van Dinther, M A H, Kurakula, K, Wiesmeijer, C C, Goumans, M-J, Bogaard, H-J, Morrell, N W, Rana, A A & ten Dijke, P 2019, ' Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension ', Journal of Pathology, vol. 249, no. 3, pp. 356-367 . https://doi.org/10.1002/path.5322
Journal of Pathology, 249(3), 356-367. John Wiley and Sons Ltd
The Journal of Pathology
Gomez-Puerto, M C, van Zuijen, I, Huang, C J Z, Szulcek, R, Pan, X, van Dinther, M A H, Kurakula, K, Wiesmeijer, C C, Goumans, M-J, Bogaard, H-J, Morrell, N W, Rana, A A & ten Dijke, P 2019, ' Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension ', Journal of Pathology, vol. 249, no. 3, pp. 356-367 . https://doi.org/10.1002/path.5322
Journal of Pathology, 249(3), 356-367. John Wiley and Sons Ltd
The Journal of Pathology
Pulmonary arterial hypertension (PAH) is characterised by an increase in mean pulmonary arterial pressure which almost invariably leads to right heart failure and premature death. More than 70% of familial PAH and 20% of idiopathic PAH patients carry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ec9507efe20052db98ba03322460ea3
http://hdl.handle.net/1887/120657
http://hdl.handle.net/1887/120657
Autor:
Janita A. Maring, Emma A. Mol, Asja T. Moerkamp, Joost P.G. Sluijter, Karien C. Wiesmeijer, Calinda K. E. Dingenouts, Janine C. Deddens, Kirsten Lodder, Marie-José Goumans, Vera Verhage, Pieter Vader, Anke M. Smits
Publikováno v:
Journal of Cardiovascular Translational Research, 12(1), 5-17. SPRINGER
Journal of Cardiovascular Translational Research
Journal of Cardiovascular Translational Research
Cell transplantation studies have shown that injection of progenitor cells can improve cardiac function after myocardial infarction (MI). Transplantation of human cardiac progenitor cells (hCPCs) results in an increased ejection fraction, but surviva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1480f7e18ae31b81e4c13435b40dcc43
https://pubmed.ncbi.nlm.nih.gov/30610671
https://pubmed.ncbi.nlm.nih.gov/30610671
Autor:
Janita A. Maring, Anke M. Smits, Karien C. Wiesmeijer, Marie-José Goumans, Wineke Bakker, Helen M. Arthur, Calinda K. E. Dingenouts, Asja T. Moerkamp, Kirsten Lodder
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189805 (2017)
PLoS ONE
PLoS ONE, 12(12)
PLoS ONE
PLoS ONE, 12(12)
AimsHereditary Hemorrhagic Telangiectasia type-1 (HHT1) is a genetic vascular disorder caused by haploinsufficiency of the TGFβ co-receptor endoglin. Dysfunctional homing of HHT1 mononuclear cells (MNCs) towards the infarcted myocardium hampers card
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08b984b50c28c2a3d974de65d7d3cbe
https://doaj.org/article/5e61c32fbfbc40819382bae5a8ae2141
https://doaj.org/article/5e61c32fbfbc40819382bae5a8ae2141
Autor:
Karien C. Wiesmeijer, Theo Rispens, Hans J. Tanke, Daniel W. Hommes, Gertjan Wolbink, Herma H. Fidder, Claudia J. de Dood, Paul L. A. M. Corstjens
Publikováno v:
Analytical and bioanalytical chemistry, 405(23), 7367-7375. Springer Verlag
Analytical and Bioanalytical Chemistry, 405(23), 7367-7375
Analytical and Bioanalytical Chemistry, 405(23), 7367-7375
Monitoring levels of biologicals against tumor necrosis factor (TNF) has been suggested to improve therapeutic outcomes in inflammatory bowel diseases (IBDs). This pilot study describes a rapid lateral flow (LF)-based assay for on-site monitoring of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84c6606bd33b428afdee4931ec57883
https://doi.org/10.1007/s00216-013-7154-0
https://doi.org/10.1007/s00216-013-7154-0
Publikováno v:
Differentiation. 76:83-90
The cell nucleus is highly organized with chromosomes occupying discrete, partially overlapping territories, and proteins that localize to specific nuclear compartments. This spatial organization of the nucleus is considered to be dynamic in response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66ef5d4e34f62dd3a6ee89d42c262b30
https://doi.org/10.1111/j.1432-0436.2007.00234.x
https://doi.org/10.1111/j.1432-0436.2007.00234.x
Autor:
Roeland W. Dirks, Nico P. Verwoerd, Tsion E. Abraham, Chris Molenaar, Hans J. Tanke, Karien C. Wiesmeijer, Ilke M. Krouwels
Publikováno v:
Journal of Cell Biology. 170:537-549
Trimethylation of histone H3 lysine 9 and the subsequent binding of heterochromatin protein 1 (HP1) mediate the formation and maintenance of pericentromeric heterochromatin. Trimethylation of H3K9 is governed by the histone methyltransferase SUV39H1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::620be40e8eaf493e0d14857c50958266
https://doi.org/10.1083/jcb.200502154
https://doi.org/10.1083/jcb.200502154