RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABAA receptors involved in volume regulation.

Autor: Camiel L C Wielders, Pim van Nierop, Tinke L Vormer, Floris Foijer, Joanne Verheij, Johannes C Lodder, Jesper B Andersen, Huibert D Mansvelder, Hein Te Riele

Publikováno v: PLoS ONE, Vol 13, Iss 5, p e0196979 (2018)

To identify coding and non-coding suppressor genes of anchorage-independent proliferation by efficient loss-of-function screening, we have developed a method for enzymatic production of low complexity shRNA libraries from subtracted transcriptomes. W

Externí odkaz: https://doaj.org/article/dce58a605b1c4907943e5f0aefa893fa

RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABAA receptors involved in volume regulation

Autor: Jesper B. Andersen, Hein te Riele, Huibert D. Mansvelder, Floris Foijer, Joanne Verheij, Pim van Nierop, Camiel L C Wielders, Johannes C. Lodder, Tinke L. Vormer

Publikováno v: PLoS ONE, Vol 13, Iss 5, p e0196979 (2018)
PLoS ONE
Wielders, C L C, van Nierop, P, Vormer, T L, Foijer, F, Verheij, J, Lodder, J C, Andersen, J B, Mansvelder, H D & Te Riele, H 2018, ' RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABA A receptors involved in volume regulation ', PLOS ONE, vol. 13, no. 5, e0196979, pp. 1-26 . https://doi.org/10.1371/journal.pone.0196979
PLoS ONE, 13(5):e0196979. Public Library of Science
PLoS ONE, 13(5):e0196979. PUBLIC LIBRARY SCIENCE
Wielders, C L C, van Nierop, P, Vormer, T L, Foijer, F, Verheij, J, Lodder, J C, Andersen, J B, Mansvelder, H D & Te Riele, H 2018, ' RNAi screening of subtracted transcriptomes reveals tumor suppression by taurine-activated GABA A receptors involved in volume regulation ', PLoS ONE, vol. 13, no. 5, e0196979 . https://doi.org/10.1371/journal.pone.0196979

To identify coding and non-coding suppressor genes of anchorage-independent proliferation by efficient loss-of-function screening, we have developed a method for enzymatic production of low complexity shRNA libraries from subtracted transcriptomes. W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88fb906328c858491668173f4f9ac868
https://doi.org/10.1371/journal.pone.0196979

Anchorage-Independent Growth of Pocket Protein-Deficient Murine Fibroblasts Requires Bypass of G2 Arrest and Can Be Accomplished by Expression of TBX2

Autor: Floris Foijer, Camiel L C Wielders, Hein te Riele, Tinke L. Vormer

Publikováno v: Molecular and Cellular Biology. 28:7263-7273

Mouse embryonic fibroblasts (MEFs) deficient for pocket proteins (i.e., pRB/p107-, pRB/p130-, or pRB/p107/p130-deficient MEFs) have lost proper G(1) control and are refractory to Ras(V12)-induced senescence. However, pocket protein-deficient MEFs exp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e50d4b8e0f87cb76ddf78b839b3ba5f
https://doi.org/10.1128/mcb.00313-08

Mumps epidemic in orthodox religious low-vaccination communities in the Netherlands and Canada, 2007 to 2009

Autor: C C, Wielders, R S, van Binnendijk, B E, Snijders, G A, Tipples, J, Cremer, E, Fanoy, S, Dolman, W l, Ruijs, H J, Boot, H E, de Melker, S J, Hahne

Publikováno v: Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 16(41)

We assessed the epidemiological characteristics of a mumps virus epidemic (genotype D) that occurred in the Netherlands between August 2007 and May 2009 and its association with a subsequent mumps outbreak in Canada. In the Netherlands, five data sou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2c875b35581336dc6af926856f8409a0
https://pubmed.ncbi.nlm.nih.gov/22008201

Epidemiology and susceptibility of 3,051 Staphylococcus aureus isolates from 25 university hospitals participating in the European SENTRY study

Autor: F.-J. Schmitz, C. L. C. Wielders, Jan Verhoef, A. C. Fluit

Publikováno v: Journal of clinical microbiology. 39(10)

A total of 3,051 methicillin-susceptible Staphylococcus aureus (MSSA) isolates and methicillin-resistant S. aureus (MRSA) isolates in Europe were compared. MRSA isolates constituted 25% of all isolates and were more prevalent in southern Europe. MRSA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166487693a5cd2f5325583e4bf5096b2
https://pubmed.ncbi.nlm.nih.gov/11574603