Zobrazeno 1 - 9
of 9
pro vyhledávání: '"C. W. Storck"'
Autor:
Marc H. Davies, Wenying Li, Jae Kwagh, Michael J. Graziano, Yongxin Zhu, C. W. Storck, Jian Wang, Kevin J Trouba, William G. Humphreys, Thomas P. Sanderson, Ang Liu, Li Ma, Oliver P. Flint, Bonnie Wang
Publikováno v:
International Journal of Toxicology. 36:35-49
BMS-986094, a 2′-C-methylguanosine prodrug for the treatment of chronic hepatitis C virus infection, was withdrawn from phase 2 clinical trials because of unexpected cardiac and renal toxicities. To better understand these toxicities, the in vitro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7b63992db0a081bfb9f91d2d2851ccb
https://doi.org/10.1177/1091581816683642
https://doi.org/10.1177/1091581816683642
Autor:
Dagmara Szkolnicka, Ferdous Khan, Baltasar Lucendo-Villarin, Claire N. Medine, Faye Wang, David C. Hay, James A. Ross, Howard M. Marriage, John P. Iredale, Mark Bradley, James R M Black, Oliver P. Flint, Salvatore Pernagallo, C. W. Storck
Publikováno v:
Stem Cells Translational Medicine. 2:505-509
Faithfully recapitulating human physiology “in a dish” from a renewable source remains a holy grail for medicine and pharma. Many procedures have been described that, to a limited extent, exhibit human tissue-specific function in vitro. In partic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::595abeaf359fd9fe4f3da054866d24ba
https://doi.org/10.5966/sctm.2012-0138
https://doi.org/10.5966/sctm.2012-0138
Autor:
Phyllis R. Wachsberger, Miriam L. Wahl, David Berd, Dennis B. Leeper, C. W. Storck, J Reilly, Ronald A. Coss
Publikováno v:
International Journal of Hyperthermia. 20:93-106
Two human melanoma cell lines, SK-Mel-28 and DB-1, were used for in vitro studies of the mechanisms underlying heat resistance of human tumour cells adapted to growth in acidic environments. Adaptation to growth at low pH was characterized by resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc6871cb73dbb254017fceb2b665e8b1
https://doi.org/10.1080/02656730310001605519
https://doi.org/10.1080/02656730310001605519
Autor:
Eric Gressen, Suzanne B. Bobyock, Phyllis R. Wachsberger, R A Coss, David Berd, C. W. Storck, A. Bhala, Dennis B. Leeper
Publikováno v:
Melanoma Research. 12:35-43
Melanoma exhibits heterogeneous growth patterns and widely varying sensitivities to multiple treatment modalities. This variability may reflect intrinsic genetic differences in factors giving rise to altered metabolism. Glucose is the primary energy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86a88156439b57afbc9338357794bd2
https://doi.org/10.1097/00008390-200202000-00006
https://doi.org/10.1097/00008390-200202000-00006
Autor:
Phyllis R. Wachsberger, J.-S. Han, Miriam L. Wahl, C. W. Storck, Ronald A. Coss, David Berd, Dennis B. Leeper
Publikováno v:
International Journal of Hyperthermia. 18:404-415
Acute acidification is being investigated as a strategy to sensitize human melanoma to 42 degrees C hyperthermia. The present study was conducted to determine the effect of hyperthermia and acute extracellular acidification on the nuclear associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72c329365aa5265bc7c098d542820e55
https://doi.org/10.1080/02656730210129745
https://doi.org/10.1080/02656730210129745
Publikováno v:
International Journal of Hyperthermia. 18:216-232
CHO cells are normally sensitized to hyperthermia by acidic pH. However, CHO cells adapted to growth in pH 6.7 medium become less sensitive to heat killing at the reduced pH. The adapted cells maintain their ability to develop thermotolerance at pH 6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5170bc59949c7999ddaa6d236f322d9c
https://doi.org/10.1080/02656730110119189
https://doi.org/10.1080/02656730110119189
Publikováno v:
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 30(1)
This study tested the ability of lonidamine (LND), a clinically applicable inhibitor of monocarboxylate transporters (MCT), to thermally sensitise human melanoma cells cultured at a tumour-like extracellular pH (pHe) 6.7.Human melanoma DB-1 cells cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78689f1d7ff16350f95d9fceda6e1876
https://pubmed.ncbi.nlm.nih.gov/24295212
https://pubmed.ncbi.nlm.nih.gov/24295212
Autor:
Michael T. Hargis, Ronald A. Coss, Leonid A. Yakubov, Eric Wickstrom, Dennis B. Leeper, C. W. Storck
Publikováno v:
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group. 20(5)
Chinese hamster ovary (CHO) cells maintained in vitro at pH 6.7 were used to model cells in the acidic environment of tumours. CHO cells grown at pH 6.7 develop thermotolerance during 42 degrees C heating at pH 6.7 and their cytoskeletal systems are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f7c4a9352dd9f26c84f6d2fae5e42a3
https://pubmed.ncbi.nlm.nih.gov/15277022
https://pubmed.ncbi.nlm.nih.gov/15277022
Autor:
Ronald A. Coss, Randy Burd, Phyllis R. Wachsberger, C. W. Storck, Adam P. Dicker, Dennis B. Leeper
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 57:S352
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c50eb751137c9629d4ff9ce14458850
https://doi.org/10.1016/s0360-3016(03)01249-5
https://doi.org/10.1016/s0360-3016(03)01249-5