Zobrazeno 1 - 10
of 141
pro vyhledávání: '"C. W. Pierce"'
Publikováno v:
The Journal of Immunology. 148:1620-1629
T cell maturation in an extrathymic environment has been studied using as a model the congenitally athymic nude mouse. Phenotypic analyses as a function of age were conducted on lymphocytes obtained from the spleens and lymph nodes of nude mice throu
Publikováno v:
The Journal of Immunology. 147:1121-1126
Phenotypic analysis of lymphocytes that mature extrathymically in congenitally athymic nude mice has revealed a large population of CD3+ CD8+ T cells that express gamma/delta-TCR. In euthymic mice, significant numbers of cells with this phenotype are
Publikováno v:
Cellular Immunology. 135:259-265
The expression of TCR by T cells that mature extrathymically in nude mice was determined by staining Ig − cells from B10 nude mice that were 5 months of age or older with mAbs specific for CD3, α β or γ δ TCR. Although the majority of Ig − ce
Publikováno v:
The Journal of Immunology. 146:1394-1401
Alloantigen-specific, radiation-resistant T cells generated in mixed-lymphocyte cultures inhibited the generation of allospecific CTL responses in vitro. This regulatory T cell population was studied using mAb generated to Ag-specific suppressor fact
Publikováno v:
Immunopharmacology. 19:39-46
IL-1-induced leukocytosis was inhibited or blocked in a dose-dependent manner by SIRS, an antigen-nonspecific suppressive lymphokine, when administered intravenously or per os to CBA mice. Timing experiments showed that SIRS effectively inhibited the
Publikováno v:
Archivum immunologiae et therapiae experimentalis. 42(2)
We have examined the antigen presenting cell (APC) function of different B cells. Resident, peritoneal B cells from normal mice were more efficient than splenic B cells in presenting antigen to CD4+ T cell lines. Peritoneal B cells from X-linked immu
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 147(4)
Phenotypic analysis of lymphocytes that mature extrathymically in congenitally athymic nude mice has revealed a large population of CD3+ CD8+ T cells that express gamma/delta-TCR. In euthymic mice, significant numbers of cells with this phenotype are
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 146(5)
Alloantigen-specific, radiation-resistant T cells generated in mixed-lymphocyte cultures inhibited the generation of allospecific CTL responses in vitro. This regulatory T cell population was studied using mAb generated to Ag-specific suppressor fact
Publikováno v:
Archivum immunologiae et therapiae experimentalis. 39(3)
Soluble immune response suppressor (SIRS), a nonspecific inhibitor of cellular and humoral immune responses and cellular proliferation, reversed IL-1-induced inhibition of autologous rosette formation by thymocytes. In addition, SIRS prevented the IL
Autor:
Bruce H. Devens, David R. Webb, G Semenuk, W. Danho, A. Koontz, R. Wesselschmidt, C W Pierce, Thomas M. Aune, Y.-C. Pan, J. Freire-Moar, R. V. Lewis, H W Schnaper, N. Mensi
Publikováno v:
International immunology. 2(8)
Soluble immune response suppressor (SIRS) is a low-molecular-weight protein (approximately 10,000 daltons) produced by mitogen- or interferon-activated T lymphocytes that can block development of humoral or cell-mediated immune responses in vivo or i