Zobrazeno 1 - 10
of 95
pro vyhledávání: '"C. W. Hughes"'
Autor:
P. L. Woodworth, C. W. Hughes
Publikováno v:
Proceedings of the International Association of Hydrological Sciences, Vol 365, Pp 11-15 (2015)
This paper describes how we are contributing to worldwide height system unification (WHSU) by using ocean models together with sea level (tide gauge and altimeter) information, geodetic (GPS and levelling) data, and new geoid models based on informat
Externí odkaz:
https://doaj.org/article/d8f807d462704569ac225a10ebb05fde
Publikováno v:
Ocean Science, Vol 10, Iss 4, Pp 701-718 (2014)
We use ocean bottom-pressure measurements from 17 tropical sites to determine the annual cycle of ocean mass. We show that such a calculation is robust, and use three methods to estimate errors in the mass determination. Our final best estimate, usin
Externí odkaz:
https://doaj.org/article/1453ce6769604dad8e41938557e5d67b
Publikováno v:
Ocean Science, Vol 10, Iss 2, Pp 215-225 (2014)
It is well-established that, at periods shorter than a year, variations in Antarctic circumpolar transport are reflected in a barotropic mode, known as the southern mode, in which sea level and bottom pressure varies coherently around Antarctica.
Externí odkaz:
https://doaj.org/article/44d9049531e1426fab76588818b005fa
Autor:
C. W. Hughes, R. J. Bingham
Publikováno v:
Ocean Science, Vol 4, Iss 1, Pp 15-29 (2008)
A review is given of the geodetic concepts necessary for oceanographers to make use of satellite gravity data to define the geoid, and to interpret the resulting product. The geoid is defined, with particular attention to subtleties related to the re
Externí odkaz:
https://doaj.org/article/5935d3519a0947e6913c8a19ce2fc1ba
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The tumor microenvironment (TME) comprises a diverse array of cells, both cancerous and non-cancerous, including stromal cells and immune cells. Complex interactions among these cells play a central role in driving cancer progression, impacting criti
Externí odkaz:
https://doaj.org/article/b8df03292d2b4b84bbc9f5afd01a7671
Autor:
Stephanie J. Hachey, Christopher J. Hatch, Daniela Gaebler, Aneela Mocherla, Kevin Nee, Kai Kessenbrock, Christopher C. W. Hughes
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-20 (2024)
Abstract Triple-negative breast cancer (TNBC) is highly aggressive with limited available treatments. Stromal cells in the tumor microenvironment (TME) are crucial in TNBC progression; however, understanding the molecular basis of stromal cell activa
Externí odkaz:
https://doaj.org/article/533691dae4ce4633bab7504995ebb266
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
The tumor microenvironment (TME) is a diverse milieu of cells including cancerous and non-cancerous cells such as fibroblasts, pericytes, endothelial cells and immune cells. The intricate cellular interactions within the TME hold a central role in sh
Externí odkaz:
https://doaj.org/article/dc0617337d014458a50b1e2f7c24b28a
Autor:
Christopher J. Hatch, Sebastian D. Piombo, Jennifer S. Fang, Johannes S. Gach, Makena L. Ewald, William K. Van Trigt, Brian G. Coon, Jay M. Tong, Donald N. Forthal, Christopher C. W. Hughes
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 11 (2024)
BackgroundSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for COVID-19, has caused nearly 7 million deaths worldwide. Severe cases are marked by an aggressive inflammatory response known as hypercytokinemia, contributing to
Externí odkaz:
https://doaj.org/article/5e25787c77e74466b0cead1fdfb7b9f3
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Endothelial cells line all major blood vessels and serve as integral regulators of many functions including vessel diameter, cellular trafficking, and transport of soluble mediators. Despite similar functions, the phenotype of endothelial ce
Externí odkaz:
https://doaj.org/article/b6eda36a51c04631b605b0e9ebd1562b
Publikováno v:
Frontiers in Human Neuroscience, Vol 16 (2022)
Port-wine birthmarks (PWBs) are caused by somatic, mosaic mutations in the G protein guanine nucleotide binding protein alpha subunit q (GNAQ) and are characterized by the formation of dilated, dysfunctional blood vessels in the dermis, eyes, and/or
Externí odkaz:
https://doaj.org/article/c6e8b80429be423e9b6302e8a0afbfe3