Zobrazeno 1 - 10
of 79
pro vyhledávání: '"C. Veiras"'
Autor:
Duo-Yao Cao, Suguru Saito, Luciana C. Veiras, Derick Okwan-Duodu, Ellen A. Bernstein, Jorge F. Giani, Kenneth E. Bernstein, Zakir Khan
Publikováno v:
Cellular & Molecular Biology Letters, Vol 25, Iss 1, Pp 1-12 (2020)
Abstract Angiotensin-converting enzyme (ACE), a dicarboxypeptidase, plays a major role in the regulation of blood pressure by cleaving angiotensin I into angiotensin II (Ang II), a potent vasoconstrictor. Because of its wide substrate specificity and
Externí odkaz:
https://doaj.org/article/94854cb79e4947a19e3ca3da80b071fd
Autor:
Zhenzi Peng, Cuiwei Liu, Aaron R. Victor, Duo-Yao Cao, Luciana C. Veiras, Ellen A. Bernstein, Zakir Khan, Jorge F. Giani, Xiaojiang Cui, Kenneth E. Bernstein, Derick Okwan-Duodu
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Granulocytes are key players in cancer metastasis. While tumor-induced de novo expansion of immunosuppressive myeloid-derived suppressor cells (MDSCs) is well-described, the fate and contribution of terminally differentiated mature neutrophils to the
Externí odkaz:
https://doaj.org/article/172498add4db402ab102601c328e4a79
Autor:
DuoYao Cao, Zakir Khan, Xiaomo Li, Suguru Saito, Ellen A Bernstein, Aaron R Victor, Faizan Ahmed, Aoi O Hoshi, Luciana C Veiras, Tomohiro Shibata, Mingtian Che, Lei Cai, Ryan E Temel, Jorge F Giani, Daniel J Luthringer, Ajit S Divakaruni, Derick Okwan-Duodu, Kenneth E Bernstein
Publikováno v:
Cardiovascular Research.
Aims The metabolic failure of macrophages to adequately process lipid is central to the etiology of atherosclerosis. Here, we examine the role of macrophage angiotensin converting enzyme (ACE) in a mouse model of PCSK9 induced atherosclerosis. Method
Autor:
Luciana C. Veiras, Ellen A. Bernstein, DuoYao Cao, Derick Okwan-Duodu, Zakir Khan, David R. Gibb, Arantxa Roach, Rachel Skelton, Ryan M. Williams, Kenneth E. Bernstein, Jorge F. Giani
Publikováno v:
Circ Res
Background: Chronic renal inflammation has been widely recognized as a major promoter of several forms of high blood pressure including salt-sensitive hypertension. In diabetes, IL (interleukin)-6 induces salt sensitivity through a dysregulation of t
Publikováno v:
Am J Physiol Cell Physiol
Kidneys continuously filter an enormous amount of sodium and adapt kidney Na+ reabsorption to match Na+ intake to maintain circulatory volume and electrolyte homeostasis. Males (M) respond to high-salt (HS) diet by translocating proximal tubule Na+/H
Autor:
Tomohiro Shibata, Duo-Yao Cao, Tahir B. Dar, Faizan Ahmed, Shabir A. Bhat, Luciana C. Veiras, Ellen A. Bernstein, Abdul Arif Khan, Manita Chaum, Stephen L. Shiao, Warren G. Tourtellotte, Jorge F. Giani, Kenneth E. Bernstein, Xiaojiang Cui, Eric Vail, Zakir Khan
Publikováno v:
Cancers; Volume 14; Issue 21; Pages: 5273
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive disease with poor prognosis, which is mainly due to drug resistance. The biology determining the response to chemo-radiotherapy in HNSCC is poorly understood. Using clinical samples
Autor:
Jorge F Giani, Luciana C Veiras, Ellen Bernstein, Duoyao Cao, Zakir Khan, Kenneth E Bernstein
Publikováno v:
Hypertension. 79
We showed that IL-1β derived from renal tubular epithelial cells initiates the inflammatory response that promotes salt sensitivity during diabetes. Yet, the intracellular mechanism that mediates IL-1β synthesis by tubular cells is unknown. We hypo
Autor:
Duo-Yao Cao, Luciana C Veiras, Justin Z Y Shen, Derick Okwan-Duodu, Zakir Khan, Kenneth E. Bernstein, Giovanna C. Regis, Jorge F. Giani, David R Gibb, Ellen A. Bernstein, Fernando P. Dominici
Publikováno v:
J Am Soc Nephrol
Background Hypertension is considered a major risk factor for the progression of diabetic kidney disease. Type 2 diabetes is associated with increased renal sodium reabsorption and salt-sensitive hypertension. Clinical studies show that men have high
Autor:
Luciana C. Veiras, Ellen Bernstein, Zakir Khan, Derick Okwan, DuoYao Cao, Faizan Ahmed, David Gibb, Kenneth Bernstein, Jorge F. Giani
Publikováno v:
The FASEB Journal. 36
Autor:
Ellen A. Bernstein, Duo-Yao Cao, Kenneth E. Bernstein, Faizan Ahmed, Zakir Khan, David R Gibb, Derick Okwan, Jorge F. Giani, Luciana C Veiras
Publikováno v:
Hypertension. 78
Renal inflammation, and specifically interleukin (IL)-6, induces salt-sensitivity in diabetic mice by upregulating the epithelial sodium channel (ENaC). However, the origin of this inflammatory response is still unknown. We hypothesize that, during d