Zobrazeno 1 - 10 of 37 pro vyhledávání: '"C. Truax"'
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Akademický článek
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Akademický článek
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3
Enrichment of C-Terminal Fragments in TAR DNA-Binding Protein-43 Cytoplasmic Inclusions in Brain but not in Spinal Cord of Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
Autor: Leo McCluskey, John Q. Trojanowski, Bruce L. Miller, Linda K. Kwong, Virginia M.-Y. Lee, Murray Grossman, Manuela Neumann, Christopher M. Clark, Kunihiro Uryu, Lauren Elman, Lionel M. Igaz, Yan Xu, Adam C. Truax
Publikováno v: The American Journal of Pathology. 173:182-194
TAR DNA-binding protein (TDP-43) has been recently described as a major pathological protein in both frontotemporal dementia with ubiquitin-positive inclusions (FTLD-U) and amyotrophic lateral sclerosis. However, little is known about the relative ab
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff4971ba4bc3fc06a3b000f3f6a0a89
https://doi.org/10.2353/ajpath.2008.080003
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4
TDP-43-Positive White Matter Pathology in Frontotemporal Lobar Degeneration With Ubiquitin-Positive Inclusions
Autor: Adam C. Truax, Linda K. Kwong, John Q. Trojanowski, Hans A. Kretzschmar, Virginia M.-Y. Lee, Bruce L. Miller, Murray Grossman, Manuela Neumann, Ben Vanmassenhove, Chrisopher M. Clark, Vivianna M. Van Deerlin
Publikováno v: Journal of Neuropathology and Experimental Neurology. 66:177-183
TDP-43 was recently identified as the major disease protein in neuronal inclusions in frontotemporal lobar degeneration with ubiquitin-positive inclusions (FTLD-U). TDP-43 is not only linked to disease mechanisms in FTLD-U, but it is also the most ro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84dd511ca22ddace36a98d8031cbc352
https://doi.org/10.1097/01.jnen.0000248554.45456.58
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5
Ubiquitinated TDP-43 in Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis
Autor: Thomas T. Chou, Adam C. Truax, Ian R. A. Mackenzie, Christopher M. Clark, Murray Grossman, Virginia M.-Y. Lee, Wolfgang Feiden, Deepak M. Sampathu, Matthew Micsenyi, Theresa Schuck, Bruce L. Miller, Manuela Neumann, Eliezer Masliah, John Q. Trojanowski, Howard Feldman, Jennifer Bruce, Hans A. Kretzschmar, Linda K. Kwong, Leo McCluskey
Publikováno v: Science. 314:130-133
Ubiquitin-positive, tau- and α-synuclein–negative inclusions are hallmarks of frontotemporal lobar degeneration with ubiquitin-positive inclusions and amyotrophic lateral sclerosis. Although the identity of the ubiquitinated protein specific to ei
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::913e461fb527039daeb527cb514f40c8
https://doi.org/10.1126/science.1134108
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6
Partial deficit of pantothenate kinase 2 catalytic activity in a case of tremor-predominant neurodegeneration with brain iron accumulation
Autor: Tsao-Wei Liang, Matthew B. Stern, Paul T. Kotzbauer, Adam C. Truax, Virginia M.-Y. Lee, John Q. Trojanowski
Publikováno v: Movement Disorders. 21:718-722
We describe an atypical case of pantothenate kinase-associated neurodegeneration (PKAN) in which slowly progressive arm tremor was the predominant symptom beginning at the age of 25, with late-onset dystonia and dysarthria developing at the age of 50
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae0afb3aee5fd379991fd690beb55ef
https://doi.org/10.1002/mds.20797
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8
Laboratory and controlled field experiments using potassium permanganate to remediate trichloroethylene and perchloroethylene DNAPLs in porous media
Autor: C. Truax, M. Schnarr, G. J. Farquhar, B. Stickney, E. Hood, T. Gonullu
Publikováno v: Journal of Contaminant Hydrology. 29:205-224
Few proven technologies exist that may be used to treat dense non-aqueous phase liquid (DNAPL) contaminants. In-situ chemical flushing is a proposed technology which consists of flushing DNAPL source zones with a reactive solution to degrade the cont
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::30f39fd5c37b81bd50250800e0ef0ec0
https://doi.org/10.1016/s0169-7722(97)00012-0
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10
Altered neuronal mitochondrial coenzyme A synthesis in neurodegeneration with brain iron accumulation caused by abnormal processing, stability, and catalytic activity of mutant pantothenate kinase 2
Autor: Virginia M.-Y. Lee, Adam C. Truax, Paul T. Kotzbauer, John Q. Trojanowski
Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 25(3)
Mutations in the pantothenate kinase 2 (PANK2) gene have been identified in patients with neurodegeneration with brain iron accumulation (NBIA; formerly Hallervorden-Spatz disease). However, the mechanisms by which these mutations cause neurodegenera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8ac7f7a6b1539c9ad17ee835c322e7
https://pubmed.ncbi.nlm.nih.gov/15659606
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