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Efficacy of nifedipine to prevent systemic and renal vasoconstrictor effects of endothelin

Autor: P. Madeddu, X. P. Yang, V. Anania, C. Troffa, A. Pazzola, A. Soro, P. Manunta, G. Tonolo, M. P. Demontis, M. V. Varoni, al. et

Publikováno v: American Journal of Physiology-Renal Physiology. 259:F304-F311

We investigated whether systemic and renal vasoconstriction induced by porcine endothelin (endothelin 1) is prevented by nifedipine in awake normotensive rats. Endothelin (0.07-1.4 nmol/kg iv) induced a long-lasting increase in mean blood pressure (M

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3dc261dab134f3e6f9c3e3e94e13ff8
https://doi.org/10.1152/ajprenal.1990.259.2.f304

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Polimorfismi del sistema renina-angiotensina in una popolazione del Nord Sardegna: associazione fra angiotensinogeno ed ipertensione arteriosa essenziale ad insorgenza precoce

Autor: N. Glorioso, C. Rozzo, C. Troffa, M. Pisano, R. Robledo, A. Soro, P. Madeddu, G. Sole, G. Patteri, E. Congeddu, M. Maioli, P.M. Melis, M. Pirastu.

Publikováno v: XIII Congresso Nazionale della Societa' Italiana dell'Ipertensione Arteriosa, Perugia, Italia, 2-5 Ottobre 1996
info:cnr-pdr/source/autori:N. Glorioso, C. Rozzo, C. Troffa, M. Pisano, R. Robledo, A. Soro, P. Madeddu, G. Sole, G. Patteri, E. Congeddu, M. Maioli, P.M. Melis, M. Pirastu./congresso_nome:XIII Congresso Nazionale della Societa' Italiana dell'Ipertensione Arteriosa/congresso_luogo:Perugia, Italia/congresso_data:2-5 Ottobre 1996/anno:1996/pagina_da:/pagina_a:/intervallo_pagine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::638696a5f8620ba2ce41890d52dea9f0
https://publications.cnr.it/doc/247736

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Different sensitivity to hydrochlorothiazide and to potassium-canrenoate among essential hypertensive patients

Autor: N, Glorioso, M G, Melis, P, Manunta, C, Troffa, G, Tonolo, A, Soro, P, Madeddu, A, Pazzola, F, Pala, D, Cusi

Publikováno v: Clinical and experimental hypertension (New York, N.Y. : 1993). 15

We compared the response of blood pressure (BP) to either K-Canrenoate (K-Can) or hydrochlorothiazide (HCTZ) in 26 mild-to-moderate essential hypertensives in a double-blind, cross-over design over 2 months each. The dose was 12.5 mg o.d. for HCTZ an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a00619638b44157a199ae664f43cb072
https://pubmed.ncbi.nlm.nih.gov/8513309

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Endothelin-1-induced renal vasoconstriction is blunted by enalaprilat and enhanced by EDRF antagonist in awake normotensive rats

Autor: P, Madeddu, V, Anania, P P, Parpaglia, C, Troffa, A, Pazzola, A, Soro, P, Manunta, G, Tonolo, M P, Demontis, M V, Varoni

Publikováno v: Clinical and investigative medicine. Medecine clinique et experimentale. 14(6)

We attempt to elucidate the putative indirect mechanisms by which endothelin-1 affects mean blood pressure and renal blood flow in normotensive awake rats. Endothelin-1 (700 pg/kg, i.v.) induced a short-lasting decrease followed by a prolonged increa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::61624bc5718b730c741277be906173aa
https://pubmed.ncbi.nlm.nih.gov/1665404

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[Protective effect of a calcium antagonist against renal vasoconstriction induced by endothelin in the normotensive rat]

Autor: P, Madeddu, F, Pala, C, Troffa, P, Pinna Parpaglia, A, Pazzola, A, Soro, P, Manunta, G, Tonolo, M G, Melis, M P, Demontis

Publikováno v: Bollettino della Societa italiana di biologia sperimentale. 66(7)

We studied the effect of nifedipine, a dihydropyridine calcium antagonist, on the hemodynamic changes induced by endothelin, in awake normotensive rats. Endothelin (0.07-1.40 nmol/kg, e.v.) caused an initial hypotensive effect, followed by long lasti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::72c232493808029d642956881565651f
https://pubmed.ncbi.nlm.nih.gov/2083061

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[Effect of chronic enalapril treatment on prorenin, renin and sex hormones during the menstrual cycle in patients with essential hypertension]

Autor: C, Troffa, G, Tonolo, P, Manunta, P, Pinna Parpaglia, P, Madeddu, M G, Melis, A, Soro, F, Pala, A, Pazzola, G, Patteri

Publikováno v: Bollettino della Societa italiana di biologia sperimentale. 66(7)

Since angiotensin II seems to be involved in the process of ovulation we studied the effect of chronic enalapril on plasma prorenin, renin, estradiol, progesterone, LH and FSH during the menstrual cycle in ten essential hypertensive women. Our data s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::efdb58c055e3eb47e3ee71a664a797cb
https://pubmed.ncbi.nlm.nih.gov/2083060

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[Effect of menstrual cycle hormones on cation transport in the red-cell membrane]

Autor: M G, Melis, C, Troffa, P, Manunta, P, Pinna Parpaglia, A, Soro, F, Pala, P, Madeddu, A, Pazzola, G, Tonolo, G, Patteri

Publikováno v: Bollettino della Societa italiana di biologia sperimentale. 66(7)

Erythrocyte cation transport, plasma prorenin and renin and sexual hormones were sequentially evaluated in 12 normal volunteers over the menstrual cycle. Na-K cotransport and Na-Li countertransport raised in 6 out of 12 subjects in synchronization wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f3c3a464f21ac87a27ef53080d615dd0
https://pubmed.ncbi.nlm.nih.gov/1964565

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Clonidine-Displacing Substance is Present in Peripheral Tissues of the Rat

Autor: N. Glorioso, C. Troffa, G. Tonolo, P. Manunta, P. Madeddu, M.G. Melis, A. Pazzola, F. Pala, M. Maioli, P. Mameli, S. Salardi, G. Bianchi

Publikováno v: American Journal of Hypertension. 2:920-923

Activation of semipurified human kidney prorenin was found to occur in vitro in presence of a mixture of lipids that mimics the composition of the inner human cell membrane. The lipid-dependent activation was indeed only partial (38 +/- 4%) when comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9eab40de0528a73b5ea483cba1bfddf8
https://doi.org/10.1093/ajh/2.12.920

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Relation Between Urinary Kallikrein Excretion and Blood Pressure Response to a Single Oral dose of Captopril

Autor: Nicola Glorioso, Paolo Madeddu, F. Bandiera, A. Soro, Alessandro Rappelli, M. C. Troffa, M. Oppes, P. Dessi-Fulgheri, Speranza Rubattu

Publikováno v: Clinical and Experimental Hypertension. Part A: Theory and Practice. 9:615-621

Thirty-one essential hypertensives with normal or low PRA were evaluated before and after a single oral dose (50 mg) of captopril. A significant fall both in systolic and diastolic blood pressure (BP) was obtained in the subgroup of patients who were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e97991eaebbff68a3b2154d1dfc0dbeb
https://doi.org/10.3109/10641968709164233

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