P398: DEVELOPMENT AND CHARACTERIZATION OF PRECLINICAL IN VIVO MODELS FOR THE IDENTIFICATION AND TESTING OF NEW THERAPEUTIC APPROACHES FOR PEDIATRIC ACUTE MYELOID LEUKEMIA

Autor: A. Da Ros, V. Indio, E. Porcù, G. Borella, M. Benetton, C. Tregnago, G. Longo, S. Cairo, B. Michielotto, S. Bresolin, B. Buldini, A. Pession, F. Locatelli, M. Pigazzi

Publikováno v: HemaSphere, Vol 6, Pp 298-299 (2022)

Externí odkaz: https://doaj.org/article/02e2f12f9360419ea5b7e76e9c3781c7

P1398: INSIGHT INTO ACUTE MYELOID LEUKEMIA INDUCED MSC SECRETOME TO REROUTE THE COURSE OF LEUKEMIA BONE MARROW NICHE

Autor: G. Borella, A. Da Ros, G. Borile, G. Longo, E. Campodoni, M. Montanari, M. Benetton, M. Sandri, C. Tregnago, F. Locatelli, M. Pigazzi

Publikováno v: HemaSphere, Vol 6, Pp 1282-1283 (2022)

Externí odkaz: https://doaj.org/article/5d5a0085cfd34dc2aca0d5a4a6d2ba53

Non-invasive detection of urothelial cancer through the analysis of driver gene mutations and aneuploidy

Autor: Simeon U Springer, Chung-Hsin Chen, Maria Del Carmen Rodriguez Pena, Lu Li, Christopher Douville, Yuxuan Wang, Joshua David Cohen, Diana Taheri, Natalie Silliman, Joy Schaefer, Janine Ptak, Lisa Dobbyn, Maria Papoli, Isaac Kinde, Bahman Afsari, Aline C Tregnago, Stephania M Bezerra, Christopher VandenBussche, Kazutoshi Fujita, Dilek Ertoy, Isabela W Cunha, Lijia Yu, Trinity J Bivalacqua, Arthur P Grollman, Luis A Diaz, Rachel Karchin, Ludmila Danilova, Chao-Yuan Huang, Chia-Tung Shun, Robert J Turesky, Byeong Hwa Yun, Thomas A Rosenquist, Yeong-Shiau Pu, Ralph H Hruban, Cristian Tomasetti, Nickolas Papadopoulos, Ken W Kinzler, Bert Vogelstein, Kathleen G Dickman, George J Netto

Publikováno v: eLife, Vol 7 (2018)

Current non-invasive approaches for detection of urothelial cancers are suboptimal. We developed a test to detect urothelial neoplasms using DNA recovered from cells shed into urine. UroSEEK incorporates massive parallel sequencing assays for mutatio

Externí odkaz: https://doaj.org/article/035e9fc0aa4749039ab3ee51913706ab

Targeting mesenchymal stromal cells plasticity to reroute acute myeloid leukemia course: MSC and AML dual targeting to treat pediatric AML

Autor: G Borella, A Da Ros, G Borile, E Porcù, C Tregnago, M Benetton, A Marchetti, V Bisio, B Montini, B Michielotto, A Cani, A Leszl, E Campodoni, M Sandri, M Montesi, S Bresolin, S Cairo, B Buldini, F Locatelli, M Pigazzi.

Publikováno v: Blood (2021).
info:cnr-pdr/source/autori:G Borella, A Da Ros, G Borile, E Porcù, C Tregnago, M Benetton, A Marchetti, V Bisio, B Montini, B Michielotto, A Cani, A Leszl, E Campodoni, M Sandri, M Montesi, S Bresolin, S Cairo, B Buldini, F Locatelli, M Pigazzi./titolo:Targeting mesenchymal stromal cells plasticity to reroute acute myeloid leukemia course: MSC and AML dual targeting to treat pediatric AML/doi:/rivista:Blood/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume

Bone marrow (BM) microenvironment contributes to the regulation of normal hematopoiesis through a finely tuned balance of self-renewal and differentiation processes, cell-cell interaction and secretion of cytokines that during leukemogenesis are alte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::7b3404bc275279409c9d510a84582006
https://publications.cnr.it/doc/456582

Expression of PD-L1 in cervical carcinoma and its impact on survival associated with T-cell infiltration and FoxP3 expression

Autor: Lessandra Michelin, Rui Norris, Fabio F. Pasqualotto, Janaina Brollo, Debora Weschenfelder, Cassiano Scholze, Floriano Riva Neto, Rafael Grochot, Sargeele Silva, André Borba Reiriz, Aline C. Tregnago

Publikováno v: Cancer Management and Research. 11:4597-4605

Background: The PD-1/PD-L1 signaling axis is currently the most elucidated mechanism for tumor evasion of T-cell-mediated immunity. Nevertheless, few data are available regarding its impact on cervical cancer and the relationship with lymphocytic inf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::75b3ab25f38c5a9a78529fb255f62990
https://doi.org/10.2147/cmar.s194597