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Immature Platelets As a Predictor of Disease Severity and Mortality in Sepsis and Septic Shock:A Systematic Review

Autor: C. Thorup, Steffen Christensen, Anne-Mette Hvas

Publikováno v: Thorup, C V, Christensen, S & Hvas, A-M 2020, ' Immature Platelets As a Predictor of Disease Severity and Mortality in Sepsis and Septic Shock : A Systematic Review ', Seminars in Thrombosis and Hemostasis, vol. 46, no. 3, pp. 320-327 . https://doi.org/10.1055/s-0039-3400256

Sepsis is associated with high morbidity and mortality, and short-term mortality remains above 30% despite relevant supportive and antibiotic treatments. The aim of this systematic review was to summarize and discuss the current evidence of the assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c01a82927455a1d30fadf8e0923fb08
https://pure.au.dk/portal/da/publications/immature-platelets-as-a-predictor-of-disease-severity-and-mortality-in-sepsis-and-septic-shock(55337c75-f609-4340-9323-33ad843526d8).html

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Effects of long-term inhibition of neuronal nitric oxide synthase on blood pressure and renin release

Autor: A. E. G. Persson, Ole Skøtt, J. Ek, C. Thorup, Anna Ollerstam

Publikováno v: Acta Physiologica Scandinavica. 173:351-358

Nitric oxide (NO) produced by neuronal NO-synthase (nNOS) in macula densa cells may be involved in the control of renin release. 7-Nitro indazole (7-NI) inhibits nNOS, and we investigated the effect of short- (4 days) and long-term (4 weeks) 7-NI tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7fd25ca802a10b4be6373716597b5104
https://doi.org/10.1046/j.1365-201x.2001.00912.x

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Renal NO production and the development of hypertension

Autor: C. Thorup, Russell D. Brown, A. E. G. Persson, Janos Pittner, A.M. Gutiérrez, Avi Ring, Ruisheng Liu, Anna Ollerstam

Publikováno v: Acta Physiologica Scandinavica. 168:169-174

The juxtaglomerular apparatus (JGA) has the very important functions of detecting the fluid flow rate to the distal tubule and thus controlling the glomerular filtration rate (GFR) (tubuloglomerular feedback mechanism [TGF]) and renin release from th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ac7f98a30e4f03d574ddb91467051cb5
https://doi.org/10.1046/j.1365-201x.2000.00669.x

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Carbon monoxide induces vasodilation and nitric oxide release but suppresses endothelial NOS

Autor: Steven S. Gross, C. Thorup, Caroline L. Jones, Leon C. Moore, Michael S. Goligorsky

Publikováno v: American Journal of Physiology-Renal Physiology. 277:F882-F889

The vascular effects of carbon monoxide (CO) resemble those of nitric oxide (NO), but it is unknown whether the two messengers converge or exhibit reciprocal feedback regulation. These questions were examined in microdissected perfused renal resistan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36709b996c450a85e4dcccba30523a57
https://doi.org/10.1152/ajprenal.1999.277.6.f882

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Production and physiological actions of anandamide in the vasculature of the rat kidney

Autor: Randy J. Krebsbach, P. C. Schmid, Sudhansu K. Dey, Sanjoy K. Das, C. Thorup, Dale G. Deutsch, Michael S. Goligorsky, George B. Stefano, H. H. O. Schmid, L. C. Moore, Gladys Arreaza

Publikováno v: Journal of Clinical Investigation. 100:1538-1546

The endogenous cannabinoid receptor agonist anandamide is present in central and peripheral tissues. As the kidney contains both the amidase that degrades anandamide and transcripts for anandamide receptors, we characterized the molecular components

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1589c321de3c4df75c6d8148db453760
https://doi.org/10.1172/jci119677

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Increased blood pressure in rats after long-term inhibition of the neuronal isoform of nitric oxide synthase

Autor: J. Pittner, A. Ollerstam, C. Thorup, A. E. G. Persson

Publikováno v: Journal of Clinical Investigation. 99:2212-2218

In the kidney, nitric oxide synthase (NOS) of the neuronal isoform (nNOS) is predominantly located in the macula densa cells. Unspecific chronic NOS inhibition in rats leads to elevated blood pressure (P(A)), associated with increased renal vascular

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::390c9cd45f3d2e23b00a11d216a2120a
https://doi.org/10.1172/jci119394

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Impaired effect of nitric oxide synthesis inhibition on tubuloglomerular feedback in hypertensive rats

Autor: C. Thorup, A. E. G. Persson

Publikováno v: American Journal of Physiology-Renal Physiology. 271:F246-F252

Experiments were conducted to compare the effects of intratubular inhibition [N omega-nitro-L-arginine (L-NNA)] of nitric oxide (NO) on the tubuloglomerular feedback (TGF) mechanism between anesthetized spontaneously hypertensive rats (SHR) and Wista

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6b4c5952c7f0ddfbfe19ee0f955f67
https://doi.org/10.1152/ajprenal.1996.271.2.f246

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Effects of acute and chronic unilateral renal denervation on the tubuloglomerular feedback mechanism

Autor: A. Ollerstam, J. Kurkus, C. Thorup, A. E. G. Persson

Publikováno v: Acta Physiologica Scandinavica. 156:139-145

We recently observed a time-dependent resetting of the tubuloglomerular feedback (TGF) sensitivity to a subnormal level after acute unilateral renal denervation (aDNX). The present investigation compares the effects of aDNX with those of chronic unil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2861788593133e194fb70306e6cbef
https://doi.org/10.1046/j.1365-201x.1996.433168000.x

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Inhibition of locally produced nitric oxide resets tubuloglomerular feedback mechanism

Autor: A. E. G. Persson, C. Thorup

Publikováno v: American Journal of Physiology-Renal Physiology. 267:F606-F611

This study was designed to compare the effects of systemic and intratubular infusions of the nitric oxide (NO) synthase inhibitor N omega-nitro-L-arginine (L-NNA) on the tubuloglomerular feedback (TGF) mechanism in anesthetized rats. We recently show

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50d35d944a78591a4c7f1a318aeaaf05
https://doi.org/10.1152/ajprenal.1994.267.4.f606

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Squamous cell carcinoma of the oral cavity in Denmark 2004-2008 - a nationwide study from DAHANCA

Publikováno v: Grau, C, Hoskin, M, Christensen, A, Rasmussen, J, Thorup, C, Mortensen, H R, Bjørnhart, B, Foged, T, Herlow, L, Jespersen, J B B, Bruhn, M A, Kristensen, C A, Buchwald, C, Lambertsen, K, Bundgaard, T, Bentzen, J, Andersen, A, Sørensen, J A, Overgaard, J & Johansen, J 2011, ' Squamous cell carcinoma of the oral cavity in Denmark 2004-2008-a nationwide study from DAHANCA ', 3rd ICHNO, International Conference on Innovative Approaches in Head & Neck Oncology, Barcelona, Spain, 24/02/2011-26/02/2011 .
University of Southern Denmark

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad205b1bca8ae1974521f25bec0ef46
https://portal.findresearcher.sdu.dk/da/publications/d32ce49d-beae-412f-9605-c848e2761303

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