Zobrazeno 1 - 10
of 15
pro vyhledávání: '"C. Thomas Lin"'
Publikováno v:
Statistics in Biopharmaceutical Research. 4:136-148
IPAC-RS developed a two-sided PTI test procedure in 2001 in response to the FDA draft guidance tests (FDA/CDER 1998; FDA/CDER 1999) for delivered dose uniformity for aerosol products. Subsequently, FDA proposed a two one-sided PTI test procedure (200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b13c80c2a2a3f931827ee6745a5d2ff
https://doi.org/10.1198/sbr.2011.10037
https://doi.org/10.1198/sbr.2011.10037
Publikováno v:
Regulatory Toxicology and Pharmacology. 60:40-45
Cynomolgus monkeys are an important and widely used species in preclinical toxicology studies. During the in-life phase of study, body weight effects may be indicative of toxicity; however, trends in body weight and body weight variability are often
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364a8bf640ec0883556f402e83514d59
https://doi.org/10.1016/j.yrtph.2011.02.001
https://doi.org/10.1016/j.yrtph.2011.02.001
Autor:
Luis E. Rodriguez, Paul A. Ellis, Mary Saltarelli, David J. LeBlond, Vincent L. Giranda, Yan Luo, C Thomas Lin, Xuesong Liu, Cherrie K. Donawho, David Frost, Robert J. Kinders, Yan Shi, Milagros Colon-Lopez, Joann P. Palma
Publikováno v:
Analytical Biochemistry. 381:240-247
Many established cancer therapies involve DNA-damaging chemotherapy or radiotherapy. The DNA repair capacity of the tumor represents a common mechanism used by cancer cells to survive DNA-damaging therapy. Poly(ADP-ribose) polymerase (PARP) is a nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448f5c504ea77024cccf092d6ede2c2b
https://doi.org/10.1016/j.ab.2008.07.007
https://doi.org/10.1016/j.ab.2008.07.007
Autor:
Sudthida Vasavanonda, Dale J. Kempf, Akhteruzzaman Molla, C. Thomas Lin, Ann Hsu, Hongmei Mo, Lixin Han
Publikováno v:
Antimicrobial Agents and Chemotherapy. 46:2249-2253
The in vitro inhibition of wild-type human immunodeficiency virus (HIV) by combinations of lopinavir and six other protease inhibitors over a range of two-drug combination ratios was evaluated. Combinations of lopinavir with indinavir, nelfinavir, am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e495d81666578326c95e9e0dc6dc6256
https://doi.org/10.1128/aac.46.7.2249-2253.2002
https://doi.org/10.1128/aac.46.7.2249-2253.2002
Publikováno v:
Journal of Statistical Planning and Inference. 104:485-501
The characterization results in probability and statistics are better known for their structural aesthetics and mathematical challenge than for their potential in the development of statistical methodology. This paper shows independence characterizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4a3c04bf0ad5b615db33caa67f15e1c
https://doi.org/10.1016/s0378-3758(01)00253-1
https://doi.org/10.1016/s0378-3758(01)00253-1
Publikováno v:
Communications in Statistics - Theory and Methods. 24:953-985
The assumption of multivariate normality is a common prac-tice in the analyses of multivariate data. But it is rarely verified, in part, because of the lack of simple and easy to use test proce-dures to detect such violations. In this paper we decomp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f95fbed3ecd70b5d6d8794e1ab2678e
https://doi.org/10.1080/03610929508831533
https://doi.org/10.1080/03610929508831533
Publikováno v:
Journal of the Royal Statistical Society: Series B (Methodological). 53:221-232
SUMMARY A method for comparing tests of normality using their 'isotones', i.e. contours on the surfaces representing P-values, is proposed. Select a family of distributions labelled by two parameters XI and X2 to represent the null and alternative hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bff1a88fa726d112158981c51583504c
https://doi.org/10.1111/j.2517-6161.1991.tb01820.x
https://doi.org/10.1111/j.2517-6161.1991.tb01820.x
Autor:
C. Thomas Lin
Publikováno v:
Drug Information Journal. 24:671-689
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59133e5e211392bc9f649b957604977b
https://doi.org/10.1177/216847909002400404
https://doi.org/10.1177/216847909002400404
Autor:
Teresa I. Ng, C. Thomas Lin, Gennadiy Koev, Lixin Han, Ping Yan, Hongmei Mo, Akhteruzzaman Molla, Tatyana Dekhtyar
Publikováno v:
Antiviral research. 73(1)
The combinations of Abbott Hepatitis C virus (HCV) polymerase A-782759 with either Boehringer Ingelheim HCV NS3 protease inhibitor BILN-2061 or interferon (IFN) displayed additive to synergistic relationships over a range of concentrations of two-dru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac74fa170d587c48f00c5815e544bd4f
https://pubmed.ncbi.nlm.nih.gov/16945431
https://pubmed.ncbi.nlm.nih.gov/16945431
Autor:
Glenn A. Reinhart, Bryan F. Cox, C. Thomas Lin, Samuel V. Calzadilla, Ryan M. Fryer, Hongyu Xu, Lee C. Preusser, Murali Gopalakrishnan, Yanhui Hu, Kennan C. Marsh
Publikováno v:
Journal of cardiovascular pharmacology. 44(2)
The therapeutic utility of K A T P channel opening agents (KCOs) in the treatment of overactive bladder may be limited by hypotension as a result of insufficient selectivity in vivo for bladder versus vasculature smooth muscle. Recently, we demonstra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::937af68753e97d49befc62f99a1f1e61
https://pubmed.ncbi.nlm.nih.gov/15243293
https://pubmed.ncbi.nlm.nih.gov/15243293