Výsledky vyhledávání

A hepatitis B vaccine formulated with a novel adjuvant system

Autor: Gerhard Wiedermann, N. Garcon, F. Ambrosch, C. Thiriart, Moncef Mohamed SmithKline Beecham Bio. s.a Slaoui, Isabelle Desombere, Geert Leroux-Roels, M. Kundi, S Thoelen

Publikováno v: Vaccine. 18:2095-2101

Although more than 95% of the vaccinated population responds to the currently licensed vaccines against hepatitis B, some groups were found to be low responders. Lipid A as adjuvant, through its ability to activate macrophages, might improve humoral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb76a66b7a9e54b1e9f7b20d828e9dbe
https://doi.org/10.1016/s0264-410x(99)00566-6

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Immunisation of macaques with SIV env recombinants: Specificity of T cell and antibody responses and evaluation of protective efficacy

Autor: K.H.G. Mills, M. Page, P. Kitchin, L. Chan, W. Jones, P. Silvera, T. Corcoran, B. Flanagan, C. Ling, C. Thiriart, M. DeWilde, C. Bruck, E. Rud, B. Clark, E.J. Stott

Publikováno v: Journal of Medical Primatology. 22:104-109

Macaques were immunised with lentil lectin purified recombinant SIVmac (BK28) derived gp160 (rgp160) with or without live vaccinia (vac)-env (BK28) priming, followed by a final boost with solid matrix antibody antigen (SMAA)-gp160 (J5) complexes and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::837794bd762c91856bb7bdd8944438e9
https://doi.org/10.1111/j.1600-0684.1993.tb00647.x

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Protection against SIV infection in macaques by immunization with inactivated virus from the BK28 molecular clone, but not with BK28‐derived recombinant env and gag proteins

Publikováno v: Journal of Medical Primatology. 21:50-58

Vaccination of cynomolgus macaques with beta-propiolactone inactivated SIVmacBK28 in Freund's adjuvant induced low but detectable levels of anti-SIV envelope (env) antibodies and T-cell responses and protected against challenge with the 32H isolate o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::17827ef08e5de00ae13c9ae54fc47385
https://doi.org/10.1111/j.1600-0684.1992.tb00567.x

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Production and of monoclonal antibodies to simian immunodeficiency virus envelope glycoproteins

Autor: C. Thiriart, K. Kent, G Stallard, L Gritz, Martin Cranage, E.J. Stott, C. Collignon, P. Silvera, T. Corcoran

Publikováno v: AIDS. 5:829-836

Eighteen monoclonal antibodies (MAb) to simian immunodeficiency virus (SIV) envelope have been characterized. All MAb were shown to bind to viral antigens on the surface of unfixed SIV-infected cells and to precipitate surface glycoproteins of SIVmac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25458988ba640a50e190cd5a59330d47
https://doi.org/10.1097/00002030-199107000-00006

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Incomplete protection, but suppression of virus burden, elicited by subunit simian immunodeficiency virus vaccines

Autor: Sally P. Mossman, C Bruck, L Fabry, Zimra R. Israel, Donald H. Maul, O Van Opstal, P F Edmonson, Francoise Bex, C Thiriart, Shawn P. O'Neil

We compared the efficacy of immunization with either simian immunodeficiency virus (SIV) Env glycoprotein (Env), Env plus Gag proteins (Gag-Env), or whole inactivated virus (WIV), with or without recombinant live vaccinia vector (VV) priming, in prot

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33d44e4a417fb9b812e8d3dafef8dbc
https://europepmc.org/articles/PMC236647/

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International collaboration comparing neutralization and binding assays for monoclonal antibodies to simian immunodeficiency virus

Autor: K. Kent, Milman G, C. Collignon, D'Souza Mp, C. Thiriart

Publikováno v: AIDS research and human retroviruses. 9(5)

Thirteen laboratories characterized a coded panel of 10 MAbs to SIVmac251 envelope protein in a collaboration organized by the National Institute of Allergy and Infectious Diseases (NIAID). The MAbs were examined against SIV isolates in neutralizatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de04b557af294e7b9d6f1858eb3980da
https://pubmed.ncbi.nlm.nih.gov/7686385

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Several antigenic determinants exposed on the gp120 moiety of HIV-1 gp160 are hidden on the mature gp120

Autor: C Thiriart, M Francotte, J Cohen, C Collignon, A Delers, S Kummert, C Molitor, D Gilles, P Roelants, F van Wijnendaele

Publikováno v: The Journal of Immunology. 143:1832-1836

Mouse mAb reactive to the HIV-1 envelope glycoprotein precursor gp160 of the HTLVIII(B) isolate were characterized in radioimmunoprecipitation and immunoblot tests with the use of HTLVIII(B) isolate as Ag. The reactivities of these mAb were also meas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c40a0873a0d2b527283a755e9ffcbe04
https://doi.org/10.4049/jimmunol.143.6.1832

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Immunization of young foxes against rabies: interaction between vaccination and natural infection

Autor: C, Thiriart, A, Iokem, F, Costy, A, Schwers, B, Brochier, A, De Meurichy, D, Peharpe, P P, Pastoret

Publikováno v: Annales de recherches veterinaires. Annals of veterinary research. 16(3)

A preliminary experiment of vaccination against rabies with a parenterally administered killed vaccine was performed in Belgium with young foxes (Vulpes vulpes L.) captured in an enzootic area (Province de Luxembourg). Out of 20 young foxes, 12 devel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ec5fe2c3a5b88f08fb57552d4eb524b
https://pubmed.ncbi.nlm.nih.gov/3904578

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Identification of two neutralizing and 8 non-neutralizing epitopes on simian immunodeficiency virus envelope using monoclonal antibodies

Autor: C. Collignon, T. Corcoran, K.A. Kent, C. Powell, Erling W. Rud, E.J. Stott, C. Thiriart

Publikováno v: Scopus-Elsevier

Ten new monoclonal antibodies (MAbs) to SIV envelope were produced and characterized. Using a panel of 28 MAbs, 10 antibody binding sites on SIV envelope protein were identified. Seven sites were located in gp120 and three in gp41. Five sites in gp12

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7232656b37ac39902e9555803e5f82ac
http://www.scopus.com/inward/record.url?eid=2-s2.0-0026753062&partnerID=MN8TOARS

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