Randomized placebo-controlled phase II trial of high-dose melatonin mucoadhesive oral gel for the prevention and treatment of oral mucositis in patients with head and neck cancer undergoing radiation therapy concurrent with systemic treatment

Autor: M. Lanzuela, I. Planas, Jordi Marruecos, Ricard Mesia, R. Morera, R. Bosser, L. Cascallar, Núria Farré, A Lozano, M G Vázquez-Masedo, G Escames, Jordi Giralt, P. Grima, J. Rubio, Vicente Valentí, C. Tarrago, Jaime Gómez-Millán

Publikováno v: Clinical & Translational Oncology
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
CLINICAL & TRANSLATIONAL ONCOLOGY
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol

Purpose The objective of this trial was to evaluate the safety and efficacy of melatonin oral gel mouthwashes in the prevention and treatment of oral mucositis (OM) in patients treated with concurrent radiation and systemic treatment for head and nec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4305f35aa2d89b40b79d82d6bc8c5b
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=4901

PO-127: Melatonin oral gel for prevention oral mucositis head and neck cancer undergoing chemo/bio radiation (MUCOMEL)

Autor: A. Escribano, B. Cirauqui, R. Bosser, I. Planas, L.A. Glaría, C. Tarrago, J. Ortiz, Ricard Mesia, V. Valenti, J. Martinez-Trufero, Núria Farré, Jordi Giralt, J. Marruecos, N. Baste, B. Castelo, R. Morera, P. Grima, A. Lozano, M. Lanzuela, A. Lopez-Pousa, J. Rubio

Publikováno v: Radiotherapy and Oncology. 122:61

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2f952f97193411de8827d86ed0553564
https://doi.org/10.1016/s0167-8140(17)30261-x

Sertaconazole: pharmacology of a gynecological antifungal agent

Autor: C Palacı́n, C. Tarrago, J. A. Ortiz

Publikováno v: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics. 71

Sertaconazole is a broad spectrum antifungal agent with excellent activity against yeasts, dermatophytes and opportunistic fungi. In addition to this antifungal efficacy, it has a good safety profile, sustained cutaneous retention, and low systemic a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb49a4b3bd01abc4e820cd3fe733d7a5
https://pubmed.ncbi.nlm.nih.gov/11118563

In vitro activity of sertaconazole against Malassezia furfur and pachydermatis in different culture media

Autor: J. A. Ortiz, C. Tarrago, C Palacı́n

Publikováno v: Methods and Findings in Experimental and Clinical Pharmacology. 20:451

The activity of sertaconazole against Malassezia furfur and pachydermatis was tested in different culture media in order to elucidate the factors that can influence its activity. The addition to the culture media of lipids, which are necessary for M.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4901ab98f3206e2f69891d4421e7a2
https://doi.org/10.1358/mf.1998.20.6.485707

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