Výsledky vyhledávání - "C. T. G. Appleton"

Global Deletion of Pannexin 3 Resulting in Accelerated Development of Aging-Induced Osteoarthritis in Mice

Autor: G. Wambiekele, Z. Y. Shao, Silvia Penuela, C. T. G. Appleton, Paxton M. Moon, Dale W. Laird, Frank Beier

Publikováno v: Bone and Joint Institute

Objective: Osteoarthritis (OA) results in pathologic changes in the joint tissue. The mechanisms driving disease progression remain largely unclear, and thus disease-modifying treatments are lacking. Pannexin 3 (Panx3) was identified as a potential m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5d6cc6585e9513ae74a52ea38d9f7d4
https://pubmed.ncbi.nlm.nih.gov/33426805

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Global analyses of gene expression in early experimental osteoarthritis

Autor: Frank Beier, C. T. G. Appleton, James L. Henry, V. Pitelka

Publikováno v: Bone and Joint Institute

Objective. To analyze genome-wide changes in chondrocyte gene expression in a surgically induced model of early osteoarthritis (OA) in rats, to assess the similarity of this model to human OA, and to identify genes and mechanisms leading to OA pathog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23b8c1e7c8bd9d448d454bd6e06b530c
https://pubmed.ncbi.nlm.nih.gov/17530714

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