A Reconstructed Human Melanoma-in-Skin Model to Study Immune Modulatory and Angiogenic Mechanisms Facilitating Initial Melanoma Growth and Invasion

Autor: Elisabetta Michielon, Marta López González, Dorian A. Stolk, Joeke G. C. Stolwijk, Sanne Roffel, Taco Waaijman, Sinéad M. Lougheed, Tanja D. de Gruijl, Susan Gibbs

Publikováno v: Cancers, 15(10):2849. Multidisciplinary Digital Publishing Institute (MDPI)
Cancers, 15(10):2849, 1-22. MDPI Multidisciplinary Digital Publishing Institute
Michielon, E, López González, M, Stolk, D A, Stolwijk, J G C, Roffel, S, Waaijman, T, Lougheed, S M, de Gruijl, T D & Gibbs, S 2023, ' A Reconstructed Human Melanoma-in-Skin Model to Study Immune Modulatory and Angiogenic Mechanisms Facilitating Initial Melanoma Growth and Invasion ', Cancers, vol. 15, no. 10, 2849, pp. 1-22 . https://doi.org/10.3390/cancers15102849
Cancers; Volume 15; Issue 10; Pages: 2849
Michielon, E, López González, M, Stolk, D A, Stolwijk, J G C, Roffel, S, Waaijman, T, Lougheed, S M, de Gruijl, T D & Gibbs, S 2023, ' A Reconstructed Human Melanoma-in-Skin Model to Study Immune Modulatory and Angiogenic Mechanisms Facilitating Initial Melanoma Growth and Invasion ', Cancers, vol. 15, no. 10, 2849 . https://doi.org/10.3390/cancers15102849

Invasion, immune modulation, and angiogenesis are crucial in melanoma progression. Studies based on animals or two-dimensional cultures poorly recapitulate the tumor-microenvironmental cross-talk found in humans. This highlights a need for more physi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f792d8b54df1e7864047e1c7d788269
https://research.vumc.nl/en/publications/e67dad4e-089b-4065-92db-f7b7ce754045

Infliximab treatment reduces depressive symptoms in patients with ankylosing spondylitis

Autor: Thea Schoonbrood, C. Stolwijk, Casper Webers, Annelies Boonen, Olga J. G. Schiepers, Robert Landewé, Astrid van Tubergen, Désirée van der Heijde

Publikováno v: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-11 (2020)
Arthritis Research and Therapy, 22(1). BMC
Arthritis Research and Therapy, 22(1):225. BioMed Central Ltd.
Arthritis Research & Therapy, 22(1):225. BioMed Central Ltd
Arthritis Research & Therapy
Arthritis research & therapy, 22(1):225. BioMed Central

Background Patients with ankylosing spondylitis (AS) are at increased risk of depression. This increased risk has been hypothesized to be solely secondary due to AS-related symptoms, or additionally due to a common inflammatory pathway. From a clinic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e927234f7e3eca23551f4ea2390bda5
https://hdl.handle.net/1887/3182984

Brief Report: Erosions and Sclerosis on Radiographs Precede the Subsequent Development of Syndesmophytes at the Same Site: A Twelve-Year Prospective Followup of Patients With Ankylosing Spondylitis

Autor: Gideon Bookelman, Désirée van der Heijde, Filip Van den Bosch, Maxime Dougados, C. Stolwijk, Astrid van Tubergen, Sofia Ramiro, Robert Landewé

Publikováno v: Arthritis & Rheumatology. 66:2773-2779

Objective: To analyze whether erosions, sclerosis, and squaring assessed on radiographs precede the development of syndesmophytes in patients with ankylosing spondylitis (AS). Methods: Patients with AS from the Outcome in Ankylosing Spondylitis Inter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3a4f6e08f5a3a4b3197db718f1967bfa
https://doi.org/10.1002/art.38775

AB0769 Does the Inclusion of Extra-Articular Manifestations Improve Validity of the Self-Administered Comorbidity Questionnaire Modified for Spondyloartritis (SPA-SCQ)? Results From Asas-Comospa

Autor: D. van der Heijde, A. Molto, Adrien Etcheto, C. Stolwijk, Ivette Essers, A. van Tubergen, Maxime Dougados, F. Van den Bosch, Robert Landewé, Annelies Boonen

Publikováno v: Annals of the Rheumatic Diseases. 74:1156.1-1156

Background The self-administered comorbidity questionnaire (SCQ) was developed to understand the impact of 13 common comorbidities on functioning and resource utilisation. In patients with AS, we recently showed that criterion- and construct validity

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4e1b3cb75e599eb403b9d7271ac88705
https://doi.org/10.1136/annrheumdis-2015-eular.2714

FRI0139 Spinal Mobility Gets Impaired in A Fixed Order in Patients with Ankylosing Spondylitis: 12-Year OASIS Results

Autor: Robert Landewé, D. van der Heijde, Maxime Dougados, S. Ramiro, A. van Tubergen, F. Van den Bosch, C. Stolwijk

Publikováno v: Annals of the Rheumatic Diseases. 73:432.2-433

Background Spinal mobility is impaired in patients with ankylosing spondylitis (AS) compared to normal subjects. However, the extent of impairment and the relative contribution of different measures are unknown. Objectives To investigate which spinal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5471f62d8f401d6947db3250b17284f4
https://doi.org/10.1136/annrheumdis-2014-eular.1841