Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer.

Autor: Maarten Neerincx, Dennis Poel, Daoud L S Sie, Nicole C T van Grieken, Ram C Shankaraiah, Floor S W van der Wolf-de Lijster, Jan-Hein T M van Waesberghe, Jan-Dirk Burggraaf, Paul P Eijk, Cornelis Verhoef, Bauke Ylstra, Gerrit A Meijer, Mark A van de Wiel, Tineke E Buffart, Henk M W Verheul

Publikováno v: PLoS ONE, Vol 13, Iss 8, p e0201809 (2018)

BACKGROUND:First line chemotherapy is effective in 75 to 80% of patients with metastatic colorectal cancer (mCRC). We studied whether microRNA (miR) expression profiles can predict treatment outcome for first line fluoropyrimidine containing systemic

Externí odkaz: https://doaj.org/article/565afe6c0e7f466f9639d433649f1fad

Contributors

Autor: Samuel Akanksha, Alessandra Allione, Juan Carlos Álvarez-Perez, Alvaro Andrades, Alberto M. Arenas, Carlos Baliñas-Gavira, Dominik A. Barth, Anna Bielowski, Roopa Biswas, Mattia Boeri, Elisabetta Broseghini, George A. Calin, Enrica Calura, Elisabetta Casalone, Vera Constâncio, Giulia Cosentino, Marina C. Costa, Carlo M. Croce, Marta Cuadros, Christine E. Cutucache, Ben Davidson, Emi Dika, Sayra Dilmac, Mihnea P. Dragomir, Rares Drula, Francisco J. Enguita, Zhaohui Feng, Manuela Ferracin, Francesca Fornari, Orazio Fortunato, André F. Gabriel, Daniel J. García, Laura Gramantieri, Rui Henrique, Wenwei Hu, Marilena V. Iorio, Carmen Jerónimo, Sakshi Kamboj, Manoj Kumar, Charles Henderson Lawrie, Ana Lúcia Leitão, Juan Liu, Francesca Lovat, Laura Masatti, Giuseppe Matullo, Pedro P. Medina, Swati Mohapatra, Vlad Moisoiu, Massimo Negrini, Vu Hong Loan Nguyen, Jacob Anderson O’Brien, Bulent Ozpolat, Barbara Pardini, Juan Rodrigo Patiño-Mercau, Laura Pazzaglia, Paola Peinado, Yuri Pekarsky, Chun Peng, George E.D. Petrescu, Martin Pichler, Ilaria Plantamura, Reuven Reich, Maria Isabel Rodriguez, Chiara Romualdi, Juan Sanjuan-Hidalgo, Katia Scotlandi, Ram C. Shankaraiah, Ondrej Slaby, Carla Solé, Dharmendra Kumar Soni, Gabriella Sozzi, Anamika Thakur, Angelo Veronese, Rosa Visone, Petra Vychytilova-Faltejskova, Cen Zhang

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::20a0b9c24c6f100a2df9d278349ce5a5
https://doi.org/10.1016/b978-0-12-822287-4.09991-6

Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer

Autor: Tineke E. Buffart, Jan Hein T.M. van Waesberghe, Henk M.W. Verheul, Jan Dirk Burggraaf, Gerrit A. Meijer, Daoud Sie, Maarten Neerincx, Nicole C.T. van Grieken, Cornelis Verhoef, Bauke Ylstra, Ram C. Shankaraiah, Paul P. Eijk, Mark A. van de Wiel, Floor S.W. Van Der Wolf-De Lijster, Dennis Poel

Publikováno v: PLoS ONE, Vol 13, Iss 8, p e0201809 (2018)
PLoS ONE, 13(8). Public Library of Science
PLoS One (online), 13(8):e0201809. Public Library of Science
PLoS ONE
PLoS ONE, 13(8):e0201809, 1-20. Public Library of Science
Neerincx, M, Poel, D, Sie, D L S, van Grieken, N C T, Shankaraiah, R C, Van Der Wolf-De Lijster, F S W, van Waesberghe, J H T M, Burggraaf, J D, Eijk, P P, Verhoef, C, Ylstra, B, Meijer, G A, van de Wiel, M A, Buffart, T E & Verheul, H M W 2018, ' Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer ', PLoS ONE, vol. 13, no. 8, e0201809, pp. 1-20 . https://doi.org/10.1371/journal.pone.0201809
Neerincx, M, Poel, D, Sie, D L S, van Grieken, N C T, Shankaraiah, R C, van der Wolf-de Lijster, F S W, van Waesberghe, J-H T M, Burggraaf, J-D, Eijk, P P, Verhoef, C, Ylstra, B, Meijer, G A, van de Wiel, M A, Buffart, T E & Verheul, H M W 2018, ' Combination of a six microRNA expression profile with four clinicopathological factors for response prediction of systemic treatment in patients with advanced colorectal cancer ', PLoS ONE, vol. 13, no. 8, pp. e0201809 . https://doi.org/10.1371/journal.pone.0201809

BACKGROUND: First line chemotherapy is effective in 75 to 80% of patients with metastatic colorectal cancer (mCRC). We studied whether microRNA (miR) expression profiles can predict treatment outcome for first line fluoropyrimidine containing systemi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cb9348eb9c6ffa77e400ad48f329797
http://www.scopus.com/inward/record.url?scp=85051341690&partnerID=8YFLogxK

Animal Models of Hepatocellular Carcinoma Prevention

Autor: Massimo Negrini, Silvia Sabbioni, Elisa Callegari, Ram C. Shankaraiah, Laura Gramantieri, Francesca Fornari

Publikováno v: Cancers

Hepatocellular carcinoma (HCC) is a deadly disease and therapeutic efficacy in advanced HCC is limited. Since progression of chronic liver disease to HCC involves a long latency period of a few decades, a significant window of therapeutic opportuniti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9324168b451a0aabda64e5725ff9b985
https://pubmed.ncbi.nlm.nih.gov/31739536

Dual endothelin receptor inhibition enhances T-DM1 efficacy in brain metastases from HER2-positive breast cancer

Autor: Dai Fukumura, Gino B. Ferraro, David P. Kodack, Christina S. F. Wong, Vasileios Askoxylakis, Mark Badeaux, Isabelle Kirst, Dan G. Duda, Rakesh K. Jain, Ram C. Shankaraiah

Publikováno v: NPJ Breast Cancer
npj Breast Cancer, Vol 5, Iss 1, Pp 1-4 (2019)

The effective treatment of cerebral metastases from HER2-positive breast cancer remains an unmet need. Recent studies indicate that activated astrocytes and brain endothelial cells exert chemoprotective effects on cancer cells through direct physical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::923c7fcff2fcbc1d0eee31ca5c87662d
http://europepmc.org/articles/PMC6333771