Zobrazeno 1 - 10
of 557
pro vyhledávání: '"C. Schaper"'
Publikováno v:
The Scientific World Journal, Vol 2012 (2012)
Background. Xenon seems to be an ideal anesthetic drug. To explore if next to the antagonism at the NMDA-receptor other molecular targets are involved, we tested the xenon requirement in short sleeping Drosophila shaker mutants and in 𝑛𝑎[ℎ
Externí odkaz:
https://doaj.org/article/cd5444907e3147acb7ac2f0c386b2e23
Autor:
Nikki C. C. Werkman, Johanna H. M. Driessen, Coen D. A. Stehouwer, Peter Vestergaard, Nicolaas C. Schaper, Joop P. van den Bergh, Johannes T. H. Nielen
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-14 (2023)
Abstract Background Numerous studies have investigated the potential association of sodium-glucose co-transporter-2 inhibitors (SGLT2-Is) with an increased risk of lower limb amputations (LLAs), but have produced conflicting results. Particularly stu
Externí odkaz:
https://doaj.org/article/a3f95621d14c45b382e75bef4239e4b7
Autor:
Frank C. T. van der Heide, Yuri D. Foreman, Iris W. M. Franken, Ronald M. A. Henry, Abraham A. Kroon, Pieter C. Dagnelie, Simone J. P. M. Eussen, Tos T. J. M. Berendschot, Jan S. A. G. Schouten, Carroll A. B. Webers, Miranda T. Schram, Carla J. H. van der Kallen, Marleen M. J. van Greevenbroek, Anke Wesselius, Casper G. Schalkwijk, Nicolaas C. Schaper, Martijn C. G. J. Brouwers, Coen D. A. Stehouwer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Retinopathy and neuropathy in type 2 diabetes are preceded by retinal nerve fibre layer (RNFL) thinning, an index of neurodegeneration. We investigated whether glucose metabolism status (GMS), measures of glycaemia, and daily glucose variabi
Externí odkaz:
https://doaj.org/article/136796e650d14f86ba6dabb1b934711c
Autor:
Marja G. J. Veugen, Veronica G. Onete, Ronald M. A. Henry, Hans-Peter Brunner-La Rocca, Annemarie Koster, Pieter C. Dagnelie, Nicolaas C. Schaper, Simone J. S. Sep, Carla J. H. van der Kallen, Martin P. J. van Boxtel, Koen D. Reesink, Johannes S. Schouten, Hans H. C. M. Savelberg, Sebastian Köhler, Frans R. Verhey, Joop P. W. van den Bergh, Miranda T. Schram, Coen D. A. Stehouwer
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Mortality in type 2 diabetes, is determined not only by classical complications, but also by comorbidities, and is linked to hyperglycaemia and apparent even in prediabetes. We aimed to comprehensively investigate, in a population-based coho
Externí odkaz:
https://doaj.org/article/1259e277d552494a811e340704024648
Autor:
Francis Q S Dzakpasu, Annemarie Koster, Neville Owen, Bastiaan E de Galan, Alison Carver, Christian J Brakenridge, Annelies Boonen, Hans Bosma, Pieter C Dagnelie, Simone J P M Eussen, Parneet Sethi, Coen D A Stehouwer, Nicolaas C Schaper, David W Dunstan
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285276 (2023)
BackgroundDetrimental associations of sedentary behaviour (time spent sitting) with musculoskeletal pain (MSP) conditions have been observed. However, findings on those with, or at risk of, type 2 diabetes (T2D) have not been reported. We examined th
Externí odkaz:
https://doaj.org/article/92a3f4e3d4274c239020ef102337ab03
Autor:
Veerle van Hulten, Cindy Sarodnik, Johanna H. M. Driessen, Nicolaas C. Schaper, Piet P. M. M. Geusens, Carol A. B. Webers, Geert-Jan Dinant, Ramon P. G. Ottenheijm, Nicklas H. Rasmussen, Rikke Viggers, Coen D. A. Stehouwer, Carla J. H. van der Kallen, Miranda T. Schram, Sandrine P. G. Bours, Pieter C. Dagnelie, Joop P. van den Bergh
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundType 2 diabetes (T2D) is frequently reported to be associated with an increased fracture risk. Epidemiological data on prevalent morphometric vertebral fractures (VFs) in T2D are sparse and even less is known in the prediabetic state.Purpos
Externí odkaz:
https://doaj.org/article/4c56f9dc04d1474bb9af9ea5836f5690
Autor:
Coen D A Stehouwer, Kristiaan Wouters, Jeroen H P M van der Velde, Jos P H Reulen, Werner Mess, Casper G Schalkwijk, Nicolaas C Schaper
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction Distal sensorimotor polyneuropathy (DSPN) is common in people with diabetes but is also found in pre-diabetes. Peripheral nerve myelin damage, which can be assessed by reduced nerve conduction velocity (NCV), is an essential feature of D
Externí odkaz:
https://doaj.org/article/c3d15e07a8534201b9a431309aba4857
Autor:
Miranda T Schram, Coen D A Stehouwer, Nicolaas C Schaper, Omar Silverman-Retana, Stephanie Brinkhues, Adam Hulman, Simone Eussen, Pieter Dagnelie, Martien C J M van Dongen
Publikováno v:
BMJ Open Diabetes Research & Care, Vol 9, Iss 1 (2021)
Introduction We compared the degree of spousal concordance in a set of detailed pathophysiological markers and risk factors for type 2 diabetes to understand where in the causal cascade spousal similarities are most relevant.Research design and metho
Externí odkaz:
https://doaj.org/article/76bd243f887a4a7b885db963ab138696
Autor:
Yuri D. Foreman, Martijn C. G. J. Brouwers, Tos T. J. M. Berendschot, Martien C. J. M. van Dongen, Simone J. P. M. Eussen, Marleen M. J. van Greevenbroek, Ronald M. A. Henry, Alfons J. H. M. Houben, Carla J. H. van der Kallen, Abraham A. Kroon, Koen D. Reesink, Miranda T. Schram, Nicolaas C. Schaper, Coen D. A. Stehouwer
Publikováno v:
Cardiovascular Diabetology, Vol 18, Iss 1, Pp 1-12 (2019)
Abstract Background Daily glucose variability may contribute to vascular complication development irrespective of mean glucose values. The incremental glucose peak (IGP) during an oral glucose tolerance test (OGTT) can be used as a proxy of glucose v
Externí odkaz:
https://doaj.org/article/052fba9f490e4de7ae2bdf7c37fc683b
Autor:
William P T M van Doorn, Yuri D Foreman, Nicolaas C Schaper, Hans H C M Savelberg, Annemarie Koster, Carla J H van der Kallen, Anke Wesselius, Miranda T Schram, Ronald M A Henry, Pieter C Dagnelie, Bastiaan E de Galan, Otto Bekers, Coen D A Stehouwer, Steven J R Meex, Martijn C G J Brouwers
Publikováno v:
PLoS ONE, Vol 16, Iss 6, p e0253125 (2021)
BackgroundClosed-loop insulin delivery systems, which integrate continuous glucose monitoring (CGM) and algorithms that continuously guide insulin dosing, have been shown to improve glycaemic control. The ability to predict future glucose values can
Externí odkaz:
https://doaj.org/article/88bd2757586d419c87a53793150f0af3