Zobrazeno 1 - 10
of 180
pro vyhledávání: '"C. Sandin"'
Autor:
C. Enerbäck, C. Sandin, S. Lambert, M. Zawistowski, P. E. Stuart, D. Verma, L. C. Tsoi, R. P. Nair, A. Johnston, J. T. Elder
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-6 (2018)
Abstract Tyrosine kinase 2 (TYK2) belongs to the Janus kinase (JAK) family of tyrosine kinases, which transmit signals from activated cytokine receptors. GWAS have consistently implicated TYK2 in psoriasis susceptibility. We performed an in-depth ass
Externí odkaz:
https://doaj.org/article/61869092989048ecba2bb37bc73b11ed
Autor:
Molly A. Taylor, Adina M. Hughes, Josephine Walton, Anna M. L. Coenen-Stass, Lukasz Magiera, Lorraine Mooney, Sigourney Bell, Anna D. Staniszewska, Linda C. Sandin, Simon T. Barry, Amanda Watkins, Larissa S. Carnevalli, Elizabeth L. Hardaker
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-16 (2019)
Abstract Background The ability to modulate immune-inhibitory pathways using checkpoint blockade antibodies such as αPD-1, αPD-L1, and αCTLA-4 represents a significant breakthrough in cancer therapy in recent years. This has driven interest in ide
Externí odkaz:
https://doaj.org/article/fdf87854fdd843649e405bcb762d5816
Autor:
Sara M. Mangsbo, Thomas H. Tötterman, Vladimir Tolmachev, Peter Ellmark, Erika Gustafsson, Anna Orlova, Linda C. Sandin
PDF file - 278K, Figure 1. Local low-dose anti-CD40 therapy generates distant anti-tumor effects and inhibits B16 tumor growth.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c049d83c93e45a6f426bfdfa05c033
https://doi.org/10.1158/2326-6066.22536251
https://doi.org/10.1158/2326-6066.22536251
Autor:
Paul D. Smith, J. Elizabeth Pease, Sabina C. Cosulich, Iain Simpson, Richard A. Ward, Clifford D. Jones, Stephen E. Fawell, Mathew J. Garnett, Patricia Jaaks, Elizabeth A. Coker, Claire Rooney, Martine P. Roudier, Sophie E. Willis, Philip Hopcroft, Michael Tonge, Karen Roberts, Joanne Wilson, Aaron Smith, Nicola Lindsay, Francis D. Gibbons, Katarzyna Falenta, Sigourney Bell, Paul Farrington, Lyndsey Hanson, Pei Zhang, Oona Delpuech, Linda C. Sandin, David Robinson, Emma J. Davies, Vikki Flemington
Primers used for targeted gene profiling on selected RAS/MAPK pathway genes either on Fluidigm or by qRT-PCR on Roche Lightcycler 480
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24be1d38b84bbeb9fe19955e7de25d2b
https://doi.org/10.1158/1535-7163.22521541
https://doi.org/10.1158/1535-7163.22521541
Autor:
Paul D. Smith, J. Elizabeth Pease, Sabina C. Cosulich, Iain Simpson, Richard A. Ward, Clifford D. Jones, Stephen E. Fawell, Mathew J. Garnett, Patricia Jaaks, Elizabeth A. Coker, Claire Rooney, Martine P. Roudier, Sophie E. Willis, Philip Hopcroft, Michael Tonge, Karen Roberts, Joanne Wilson, Aaron Smith, Nicola Lindsay, Francis D. Gibbons, Katarzyna Falenta, Sigourney Bell, Paul Farrington, Lyndsey Hanson, Pei Zhang, Oona Delpuech, Linda C. Sandin, David Robinson, Emma J. Davies, Vikki Flemington
Supplementary Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8cb1ae292b59622591433bfe72565e
https://doi.org/10.1158/1535-7163.22521556
https://doi.org/10.1158/1535-7163.22521556
Autor:
Sara M. Mangsbo, Thomas H. Tötterman, Vladimir Tolmachev, Peter Ellmark, Erika Gustafsson, Anna Orlova, Linda C. Sandin
PDF file - 195K, Figure 3. In vivo biodistribution of target organs 48h and 72h post injection of 125I-CD40-specific and 131I-rat IgG2a control antibody.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2449e656e103e10d03dd3e6e09a247ad
https://doi.org/10.1158/2326-6066.22536242
https://doi.org/10.1158/2326-6066.22536242
Autor:
Sara M. Mangsbo, Thomas H. Tötterman, Vladimir Tolmachev, Peter Ellmark, Erika Gustafsson, Anna Orlova, Linda C. Sandin
Immunotherapy with intratumoral injection of adenoviral vectors expressing CD40L has yielded positive results in experimental and clinical bladder cancer. We therefore hypothesized that anti-CD40 antibody would be effective in this setting. Agonistic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51984d82bb114cbee2ac57e0754c1b08
https://doi.org/10.1158/2326-6066.c.6548084.v1
https://doi.org/10.1158/2326-6066.c.6548084.v1
Autor:
Paul D. Smith, J. Elizabeth Pease, Sabina C. Cosulich, Iain Simpson, Richard A. Ward, Clifford D. Jones, Stephen E. Fawell, Mathew J. Garnett, Patricia Jaaks, Elizabeth A. Coker, Claire Rooney, Martine P. Roudier, Sophie E. Willis, Philip Hopcroft, Michael Tonge, Karen Roberts, Joanne Wilson, Aaron Smith, Nicola Lindsay, Francis D. Gibbons, Katarzyna Falenta, Sigourney Bell, Paul Farrington, Lyndsey Hanson, Pei Zhang, Oona Delpuech, Linda C. Sandin, David Robinson, Emma J. Davies, Vikki Flemington
Supplementary Figure 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d656816b18c3ad9cb8c303b7ebd7f0b
https://doi.org/10.1158/1535-7163.22521559
https://doi.org/10.1158/1535-7163.22521559
Autor:
Paul D. Smith, J. Elizabeth Pease, Sabina C. Cosulich, Iain Simpson, Richard A. Ward, Clifford D. Jones, Stephen E. Fawell, Mathew J. Garnett, Patricia Jaaks, Elizabeth A. Coker, Claire Rooney, Martine P. Roudier, Sophie E. Willis, Philip Hopcroft, Michael Tonge, Karen Roberts, Joanne Wilson, Aaron Smith, Nicola Lindsay, Francis D. Gibbons, Katarzyna Falenta, Sigourney Bell, Paul Farrington, Lyndsey Hanson, Pei Zhang, Oona Delpuech, Linda C. Sandin, David Robinson, Emma J. Davies, Vikki Flemington
KRAS mutation status of cell lines included in in vitro combination screen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2948856a623204b2bfff5869f7d00b5e
https://doi.org/10.1158/1535-7163.22521529.v1
https://doi.org/10.1158/1535-7163.22521529.v1
Autor:
Sara M. Mangsbo, Thomas H. Tötterman, Vladimir Tolmachev, Peter Ellmark, Erika Gustafsson, Anna Orlova, Linda C. Sandin
PDF file - 68K, Table 3: In vivo biodistribution 48h (also see Supplementary Fig. S3A). Statistical differences calculated between anti-CD40 and rat IgG2a and the two administration routes (n=4, Student?s paired t-test).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::042dc6b3d4078ffc2a7291bb49f1e09f
https://doi.org/10.1158/2326-6066.22536230
https://doi.org/10.1158/2326-6066.22536230