Zobrazeno 1 - 10
of 14
pro vyhledávání: '"C. S. Sanderson"'
Publikováno v:
Cytotechnology. 34:71-82
The infection of insect cells with baculovirus was described in a mathematical model as a part of the structured dynamic model describing whole animal cell metabolism. The model presented here is capable of simulating cell population dynamics, the co
Publikováno v:
Biochemical Engineering Journal. 3:213-218
A detailed, structured animal cell model has a number of interesting potential applications. In this paper, a structured model will be `tuned' to data for two different murine hybridoma cell lines, 2HG11 and AFP27. With an appropriate set of paramete
Publikováno v:
Biochemical Engineering Journal. 3:203-211
There are a substantial number of applications for mathematical models in the field of cell culture technology. A number of currently available animal cell culture models are identified and detailed. A structured model that is capable of addressing a
Publikováno v:
Biochemical Engineering Journal. 3:219-229
Viral infection can have significant effects on the behaviour of cell cultures and the interaction of baculoviruses with insect cells is currently of particular interest. This paper examines a number of existing mathematical models for this phenomeno
Publikováno v:
Hong Kong University of Science and Technology
This paper presents a novel method for the system identification of the fed-batch fermentation process defined in the problem statement of the Biotechnological Control Forum Modelling and Control Competition. The identification methodology involves a
Publikováno v:
Cytotechnology. 23:13-17
In animal cell culture, there are some 25 substrates that both have a significant effect on the culture performance and which can be measured with relative ease. A detailed dynamic simulation for such a culture has been produced and an optimisation p
Publikováno v:
Cytotechnology. 21:149-153
Recent advances in computer technology have promoted the design and use of detailed, computer-based models for biological systems. For many non-biological systems, the complexity of such simulations may be considered inappropriate and unwieldy, but i
Publikováno v:
Computers & Chemical Engineering. 19:681-686
A dynamic model for the growth of animal cells in culture is used in combination with an optimisation algorithm to design a medium for improved cell growth. By manipulating the initial concentrations of glucose and glutamine, the model predicts that
Publikováno v:
IFAC Proceedings Volumes. 28:334-337
This paper describes an extension to a previously developed, dynamic model for animal cell metabolism. This extension is capable of describing viral infection and multiplication and, in keeping with the whole cell model, is generic in form. It has be
Publikováno v:
Cytotechnology. 23(1-3)
In animal cell culture, there are some 25 substrates that both have a significant effect on the culture performance and which can be measured with relative ease. A detailed dynamic simulation for such a culture has been produced and an optimisation p