Zobrazeno 1 - 10
of 243
pro vyhledávání: '"C. S. Paulose"'
Publikováno v:
Biochemistry and Cell Biology. 96:433-440
Temporal lobe epilepsy involves a sequence of events that can lead to neurotransmitter signalling alterations. There are many herbal extracts considered to be alternative therapeutic methods to manage epilepsy. In this study, we investigated the effe
Publikováno v:
The Journal of Nutritional Biochemistry. 26:1041-1049
Pancreatic islets, particularly insulin-secreting β cells, share common characteristics with neurons. Glutamate is one of the major excitatory neurotransmitter in the brain and pancreas, and its action is mediated through glutamate receptors. In the
Publikováno v:
Journal of Biomedical Nanotechnology. 10:622-631
Use of nanoparticulate drug delivery system for an effective therapeutic outcome against diseases gains immense hope in the study of drug delivery to partially hepatectomised rats. In the present study, partially hepatectomised rats treated with Gamm
Autor:
J. Shilpa, C. S. Paulose
Publikováno v:
Journal of Materials Science: Materials in Medicine. 25:1721-1735
The metabolic alterations resulted from hepatic injury and cell loss lead to synaptic defects and neurodegeneration that undoubtedly contribute motor deficits. In the present study, GABA and 5-HT chitosan nanoparticles mediated liver cell proliferati
Publikováno v:
Journal of the Neurological Sciences. 331:31-37
article i nfo Oxidative stress-induced neuronal cell death has been implicated in Parkinson's disease (PD). Oxidative stress ini- tiated by 6-hydroxydopamine (6-OHDA) causes mitochondrial dysfunction leading to apoptosis and Parkinsonian neurodegener
Publikováno v:
Journal of Neuroscience Research. 91:1203-1214
γ-Aminobutyric acid (GABA)- and serotonin (5-HT)-mediated cell signaling, neuronal survival enhancement, and reduced neuronal death in brainstem during liver injury followed by active liver regeneration have a critical role in maintaining routine bo
Publikováno v:
Chemico-Biological Interactions. 201:39-48
Functional activity of neurotransmitter receptor and their sensitivity to regulation are altered in DM. We evaluated the neuroprotective effect of curcumin in glutamate mediated excitotoxicity in cerebral cortex of streptozotocin induced diabetic rat
Publikováno v:
European Journal of Pharmacology. 696:54-61
The incidence of type 2 diabetes mellitus is rising at alarming proportions. Central nervous system plays an important part in orchestrating glucose metabolism, with accumulating evidence linking dysregulated central nervous system circuits to the fa
Publikováno v:
Journal of Materials Science: Materials in Medicine. 23:2913-2921
The development of nanoparticles containing active molecules having improved stability, sustained release and maximum half life helps in cell proliferation result in enhanced tissue regeneration. Our study focuses on the use of Gamma amino butyric ac
Publikováno v:
European Journal of Pharmacology. 687:14-20
Diabetes mellitus is a heterogeneous disease and nutritional therapy forms a necessary dimension for its long-term management. Traditional medicinal plants and vitamins are the potentially useful natural products for diabetes control. Diabetes causes