Zobrazeno 1 - 3
of 3
pro vyhledávání: '"C. Ryland Ill"'
Publikováno v:
bioRxiv
Many cancers harbor pro-proliferative mutations of the mitogen-activated protein kinase (MAPK) pathway and many targeted inhibitors now exist for clinical use, but drug resistance remains a major issue. We recently showed that BRAF-driven melanoma ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ab42bc85da173967f1f2fb71a4ff2c6
https://doi.org/10.1101/2023.03.17.533211
https://doi.org/10.1101/2023.03.17.533211
Autor:
Mansi Arora, Justin Moser, Timothy E. Hoffman, Lotte P. Watts, Mingwei Min, Monica Musteanu, Yao Rong, Jordan Schneider, C Ryland Ill, Varuna Nangia, Manuel Sanclemente, John Lapek, Lisa Nguyen, Sherry Niessen, Stephen Dann, Todd van Arsdale, Mariano Barbacid, Nichol Miller, Sabrina L. Spencer
Publikováno v:
Cancer Research. 83:5992-5992
CDK2 is a core cell-cycle enzyme that phosphorylates a variety of substrates to drive progression through the cell cycle. CDK2 is hyperactivated in multiple cancers and is therefore an attractive therapeutic target. Here, application of a novel small
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a6262ebc0d17cc970398e20e0286827
https://doi.org/10.1158/1538-7445.am2023-5992
https://doi.org/10.1158/1538-7445.am2023-5992
Autor:
Hoffman, Timothy E., Nangia, Varuna, Ill, C. Ryland, Passanisi, Victor J., Armstrong, Claire, Yang, Chen, Spencer, Sabrina L.
Publikováno v:
Science Signaling; 8/1/2023, Vol. 16 Issue 796, p1-18, 18p