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pro vyhledávání: '"C. Ruttan"'
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 9, Pp 945-958 (2019)
Abstract In preclinical studies, mesenchymal stromal cells (MSCs) exhibit robust potential for numerous applications. To capitalize on these benefits, cell manufacturing and delivery protocols have been scaled up to facilitate clinical trials without
Externí odkaz:
https://doaj.org/article/a9a4c13dcb8648c8b5146261ff68c547
Publikováno v:
Cytotherapy. 20:S30
Autor:
Cindy C. Ruttan, Barry W. Glickman
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 509:175-200
DNA repair is essential for the maintenance of genomic integrity. Consequently, altered repair capacity may impact individual health in such areas as aging and susceptibility to certain diseases. Defects in some DNA repair genes, for example, have be
Publikováno v:
Environmental and Molecular Mutagenesis. 38:209-215
ERCC1 plays an essential role in the nucleotide excision repair (NER) of DNA. We compare 37 kb of sequence from the ERCC1 region on human chromosome 19q13.3 to the orthologous region on mouse chromosome 7. In addition to showing the conserved gene st
Publikováno v:
Carcinogenesis. 21(11)
Variation in gene coding sequence represents a significant factor in predisposition to disease, including cancer. Variants of some DNA repair genes (e.g. MLH1, MSH2 and MSH6) are known to predispose to cancer. We identified single nucleotide polymorp
Akademický článek
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