Zobrazeno 1 - 10
of 366
pro vyhledávání: '"C. Rouse"'
Autor:
L.M. Soanes, S. Pike, D. Barker, C. Butt, L. John, K. Medcalf, E. Naumann, C. Rouse, C.A. Samuel, F. Mukhida
Publikováno v:
Nature-Based Solutions, Vol 4, Iss , Pp 100095- (2023)
The islands of the Caribbean are particularly susceptible to the effects of climate change due to their low-lying coastal areas and location within the Atlantic basin's hurricane belt. The UK Overseas Territory of Anguilla is one such island. The pre
Externí odkaz:
https://doaj.org/article/27d16921610d4e60b9bdf7db285fa1c9
Autor:
Mingyue Li, Victor A. Beaumont, Shahajahan Akbar, Hannah Duncan, Arch Creasy, Wenge Wang, Kelly Sackett, Lisa Marzilli, Jason C. Rouse, Hai-Young Kim
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTThe higher order structure (HOS) of monoclonal antibodies (mAbs) is an important quality attribute with strong contribution to clinically relevant biological functions and drug safety. Due to the multi-faceted nature of HOS, the synergy of mu
Externí odkaz:
https://doaj.org/article/c60148f3693e491c9f2b5b111def14a8
Autor:
Andrew C. Rouse
Publikováno v:
Studia Ethnologica Pragensia, Iss 1, Pp 195-208 (2023)
There are a significant number of songs with a ‘broken motif ’, that they are seen as their own category or type of song. But to what extent is the idea of two young people splitting an object and keeping half each, seen as declaration of their u
Externí odkaz:
https://doaj.org/article/933d9239f9044130aa10ee5e7b4bfd78
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301668 (2024)
BackgroundTelerehabilitation is a term to describe rehabilitation services delivered via information and communication technology. Such services are an increasingly important component for the management of rheumatic and musculoskeletal diseases (RMD
Externí odkaz:
https://doaj.org/article/cce65549e028468ea86f888591f373aa
Autor:
Renée Procopio-Melino, Frank W. Kotch, Amar S. Prashad, Jose M. Gomes, Wenge Wang, Bo Arve, Andrew Dawdy, Lawrence Chen, Justin Sperry, Christine Hosselet, Tao He, Ronald Kriz, Laura Lin, Kimberly Marquette, Lioudmila Tchistiakova, Will Somers, Jason C. Rouse, Xiaotian Zhong
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Next-generation site-specific cysteine-based antibody–drug-conjugates (ADCs) broaden therapeutic index by precise drug-antibody attachments. However, manufacturing such ADCs for clinical validation requires complex full reduction and reoxi
Externí odkaz:
https://doaj.org/article/5cda877d16ac4d3e838e8490f8f4c4f8
Autor:
Rameswari Chilamakuri, Danielle C. Rouse, Yang Yu, Abbas S. Kabir, Aaron Muth, Jianhua Yang, Jeffery M. Lipton, Saurabh Agarwal
Publikováno v:
Translational Oncology, Vol 15, Iss 1, Pp 101272- (2022)
High-risk neuroblastoma (NB) represents a major clinical challenge in pediatric oncology due to relapse of metastatic, drug-resistant disease, and treatment-related toxicities. An analysis of 1235 primary NB patient dataset revealed significant incre
Externí odkaz:
https://doaj.org/article/876fff3a8ac947789e0b637412ec2d83
Autor:
Gayathri R Devi, Dorababu Sannareddy, Alexandra Bennion, Ashlyn Rickard, Douglas C Rouse, Mark W Dewhirst, Gregory M Palmer
Publikováno v:
Cancer Research. 83:P3-08
Background: Lymphovascular invasion (LVI) is a major route of metastatic dissemination and recent studies indicate its value as an independent prognostic indicator for advanced breast, colorectal, squamous cell, prostate, brain cancers. LVI is a clin
Autor:
Andrew C. Rouse
Publikováno v:
FOCUS: Papers in English Literary and Cultural Studies. 11:45-56
In 1683 the Ottoman Turks were defeated at Vienna in what was to be a last serious bid to extend their empire further west, crushing the Habsburg dynasty as they did so. They had had good reason to believe the venture viable, as there existed no stab
Publikováno v:
Antibodies, Vol 11, Iss 1, p 5 (2022)
Glycans as sugar polymers are important metabolic, structural, and physiological regulators for cellular and biological functions. They are often classified as critical quality attributes to antibodies and recombinant fusion proteins, given their imp
Externí odkaz:
https://doaj.org/article/d86b2f7fc5674a1b9c7cf7c6ad10df18
Autor:
Pratiksha I. Thakore, Jennifer B. Kwon, Christopher E. Nelson, Douglas C. Rouse, Matthew P. Gemberling, Matthew L. Oliver, Charles A. Gersbach
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Repression of gene transcription using CRISPR-Cas9 has been achieved in vitro but not for delivery into adult animal models. Here, the authors use AAV8 to deliver the transcriptional repressor dSaCas9KRAB to the cholesterol regulator Pcsk9, and show
Externí odkaz:
https://doaj.org/article/46f1559feeb54a51902bab3a11b455bc