Zobrazeno 1 - 10
of 57
pro vyhledávání: '"C. Ronald Geyer"'
Autor:
Ashley R. Sutherland, Brijesh Parlekar, David W. Livingstone, Andrés X. Medina, Wendy Bernhard, Tays Hernández García, John DeCoteau, C. Ronald Geyer
Publikováno v:
Journal of Nanobiotechnology, Vol 22, Iss 1, Pp 1-13 (2024)
Abstract Background Adoptive cell cancer therapies aim to re-engineer a patient’s immune cells to mount an anti-cancer response. Chimeric antigen receptor T and natural killer cells have been engineered and proved successful in treating some cancer
Externí odkaz:
https://doaj.org/article/cb8f4f0df89549488e5fbe56f8fd5d8c
Autor:
Landon Pastushok, Shrutii Sarda, Karen Mochoruk, Wayne Hill, Loni T. Pickle, Michelle Toro, Carolina Gonzalez, Stephanie Ostresh, Timothy J. Looney, Chenchen Yang, Julie Stakiw, Mark J. Bosch, Hadi Goubran, C. Ronald Geyer, Geoffrey M. Lowman, John F. DeCoteau
Publikováno v:
Journal of Molecular Pathology, Vol 5, Iss 1, Pp 45-65 (2024)
B-cell neoplasms possess clonal B-cell receptor rearrangements (BCR clonotype lineages) that can be identified by sequencing the B-cell repertoire for use in diagnostics, risk stratification, and high-sensitivity monitoring. BCR somatic hypermutation
Externí odkaz:
https://doaj.org/article/da7a5fbbb6434fb9a56fc2e46e4e3bc9
Autor:
Wendy Bernhard, Kris Barreto, Darien Toledo, Ayman El-Sayed, Kimberly A. Jett, Angel Casaco, Humphrey Fonge, C. Ronald Geyer
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-9 (2023)
Abstract Molecular-targeted imaging probes can be used with a variety of imaging modalities to detect diseased tissues and guide their removal. EGFR is a useful biomarker for a variety of cancers, because it is expressed at high levels relative to no
Externí odkaz:
https://doaj.org/article/bed93400588348b38db2a18420019388
Autor:
Md. Kausar Alam, Michelle Brabant, Raja Solomon Viswas, Kris Barreto, Humphrey Fonge, C. Ronald Geyer
Publikováno v:
BMC Biotechnology, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Advances in antibody engineering provide strategies to construct recombinant antibody-like molecules with modified pharmacokinetic properties. Multermerization is one strategy that has been used to produce antibody-like molecules
Externí odkaz:
https://doaj.org/article/26a22009f4c34a498dfba0e5984274b3
Autor:
Md. Fahmid Islam, Atsushi Watanabe, Lai Wong, Conor Lazarou, Frederick S. Vizeacoumar, Omar Abuhussein, Wayne Hill, Maruti Uppalapati, C. Ronald Geyer, Franco J. Vizeacoumar
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Next generation sequencing is becoming the method of choice for functional genomic studies that use pooled shRNA or CRISPR libraries. A key challenge in sequencing these mixed-oligo libraries is that they are highly susceptible to hairpin an
Externí odkaz:
https://doaj.org/article/89b483b604f54dc19de4121b5e8ea367
Publikováno v:
Bioconjugate chemistry. 33(5)
Microbubbles are ultrasound contrast agents that can adhere to disease-related vascular biomarkers when functionalized with binding ligands such as antibodies or peptides. The biotin-streptavidin approach has predominantly been used as the microbubbl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9663102b4d4aca70c470d2faedfd2dba
https://pubmed.ncbi.nlm.nih.gov/35427123
https://pubmed.ncbi.nlm.nih.gov/35427123
Publikováno v:
Molecular imaging and biology.
Our objectives were to develop a targeted microbubble with an anti-P-selectin aptamer and assess its ability to detect bowel inflammation in two murine models of acute colitis.Lipid-shelled microbubbles were prepared using mechanical agitation. A rap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::169b457034de2c1fe5d11554913814ec
https://pubmed.ncbi.nlm.nih.gov/35851673
https://pubmed.ncbi.nlm.nih.gov/35851673
Publikováno v:
Cancers
Cancers, Vol 14, Iss 300, p 300 (2022)
Cancers; Volume 14; Issue 2; Pages: 300
Cancers, Vol 14, Iss 300, p 300 (2022)
Cancers; Volume 14; Issue 2; Pages: 300
Simple Summary The immune system responds to abnormal cell growth by sending immune cells to kill them. The immune cell response is very important since it can usually stop abnormal cells from growing and spreading. Immuno-therapeutics used to treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1988fde5ec0f71930edf6f4e88e4fb
http://europepmc.org/articles/PMC8773629
http://europepmc.org/articles/PMC8773629
Publikováno v:
Therapeutic Antibodies ISBN: 9781071614495
Phage display is commonly used to select target-binding antibody fragments from large libraries containing billions of unique antibody clones. In practice, selection outputs are often highly heterogenous, making it desirable to recover sequence infor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e731200b4c62de0bb3a1d7889a2b91c
https://doi.org/10.1007/978-1-0716-1450-1_6
https://doi.org/10.1007/978-1-0716-1450-1_6
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2313
Phage display is commonly used to select target-binding antibody fragments from large libraries containing billions of unique antibody clones. In practice, selection outputs are often highly heterogenous, making it desirable to recover sequence infor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0761fc7b5548d591fbe3278688b28d33
https://pubmed.ncbi.nlm.nih.gov/34478134
https://pubmed.ncbi.nlm.nih.gov/34478134