Zobrazeno 1 - 9
of 9
pro vyhledávání: '"C. Robbie Waites"'
Autor:
C. Robbie Waites, Jeffrey D. Moehlenkamp, Amy J. Reisinger, Lora L. Arnold, Sarah H. Tannehill-Gregg, Samuel M. Cohen, Beth E. Schilling, David A. Stock, Thomas P. Sanderson, Mark A. Dominick
Publikováno v:
Toxicologic Pathology. 37:293-305
In carcinogenicity studies with PPAR γ and α/γ agonists, urinary bladder tumors have been reported in Harlan Sprague-Dawley (HSD) and Charles River Sprague-Dawley (SD) but not Wistar (WI) rats, with urolithiasis purported to be the inciting event.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71826813dbfdeefa291c53c769ef4fe7
https://doi.org/10.1177/0192623309332990
https://doi.org/10.1177/0192623309332990
Autor:
Samuel M. Cohen, James Mitroka, Martin Cano, Mark A. Dominick, M. Randy White, C. Robbie Waites, Lora L. Arnold, Terry Van Vleet, Thomas P. Sanderson, Beth E. Schilling
Publikováno v:
Toxicological Sciences. 96:58-71
Muraglitazar, a PPARa/g dual agonist, was dosed orally to rats once daily for 13 weeks to evaluate urinary and urothelial changes of potential relevance to urinary bladder tumorigenesis. Groups of 17 young or aged rats per sex were fed a normal or 1%
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e537d87061d08b00aeab171e37a4f68
https://doi.org/10.1093/toxsci/kfl176
https://doi.org/10.1093/toxsci/kfl176
Autor:
Calvert Louden, Timothy K. Hart, C. Robbie Waites, Anne M. Klinkner, William D. Kerns, Peter J. Bugelski
Publikováno v:
Journal of Histochemistry & Cytochemistry. 45:743-753
SUMMARY We introduce here a new fluorescence microscopy technique for en face analysis of the atherosclerotic fatty streaks (FS). This technique is semiquantitative and has the sensitivity and resolution to map lipids to individual cells in FS less t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d557d644dc9d58998baa1798e714e01
https://doi.org/10.1177/002215549704500513
https://doi.org/10.1177/002215549704500513
Autor:
Amy J, Reisinger, Sarah H, Tannehill-Gregg, C Robbie, Waites, Mark A, Dominick, Beth E, Schilling, Todd A, Jackson
Publikováno v:
Journal of the American Association for Laboratory Animal Science : JAALAS. 48(2)
A novel therapeutic compound was found to induce bladder tumors in male rats. Given the location of the tumors and the increased amounts of calcium- and magnesium-containing solids found in the urine of treated animals, we hypothesized that tumorigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::403b2c1cf6719e40b4a1451ecfa820c3
https://pubmed.ncbi.nlm.nih.gov/19383209
https://pubmed.ncbi.nlm.nih.gov/19383209
Autor:
C. Robbie Waites, Thomas P. Sanderson, Borge M. Ulland, Mark A. Dominick, Richard W. Voelker, Daniel Minnema, Sarah H. Tannehill-Gregg, Samuel M. Cohen, Beth E. Schilling, Lora L. Arnold
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 98(1)
The carcinogenic potential of muraglitazar, a dual human peroxisome proliferator-activated receptor alpha/gamma agonist, was evaluated in 2-year studies in mice (1, 5, 20, and 40 mg/kg) and rats (1, 5, 30, and 50 mg/kg). Benign gallbladder adenomas o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0344809c65c4b8b32830af41ea870ae5
https://pubmed.ncbi.nlm.nih.gov/17426106
https://pubmed.ncbi.nlm.nih.gov/17426106
Autor:
Terry R, Van Vleet, M Randy, White, Thomas P, Sanderson, Samuel M, Cohen, Martin, Cano, Lora L, Arnold, C Robbie, Waites, Beth E, Schilling, James, Mitroka, Mark A, Dominick
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 96(1)
Muraglitazar, a PPARalpha/gamma dual agonist, was dosed orally to rats once daily for 13 weeks to evaluate urinary and urothelial changes of potential relevance to urinary bladder tumorigenesis. Groups of 17 young or aged rats per sex were fed a norm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::741b2819357622e5d66328c59bb286c1
https://pubmed.ncbi.nlm.nih.gov/17132713
https://pubmed.ncbi.nlm.nih.gov/17132713
Autor:
Peter J. Bugelski, Anne M. Klinkner, C. Robbie Waites, Timothy K. Hart, Beverly E. Maleeff, William D. Kerns
Publikováno v:
Proceedings, annual meeting, Electron Microscopy Society of America. 52:352-353
Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG CoAR) have been shown to inhibit cell growth and to affect cell differentiation in a variety of in vitro systems. The human colon carcinoma cell line CaCo-2, when grown on permeable m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75410ad002cfd0f2ab65cdfadadd7c96
https://doi.org/10.1017/s0424820100169493
https://doi.org/10.1017/s0424820100169493
Autor:
Terry R. Van Vleet, M. Randy White, Thomas P. Sanderson, Samuel M. Cohen, Martin Cano, Lora L. Arnold, C. Robbie Waites, Beth E. Schilling, James Mitroka, Mark A. Dominick
Publikováno v:
Toxicological Sciences; Mar2007, Vol. 96 Issue 1, p58-71, 14p
Autor:
Sarah H. Tannehill-Gregg, Thomas P. Sanderson, Daniel Minnema, Richard Voelker, Borge Ulland, Samuel M. Cohen, Lora L. Arnold, Beth E. Schilling, C. Robbie Waites, Mark A. Dominick
Publikováno v:
Toxicological Sciences; Jul2007, Vol. 98 Issue 1, p258-258, 1p